| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the naftopidil-2911 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACSL6 | acyl-CoA synthetase long-chain family member 6 |
| ADTRP | androgen-dependent TFPI-regulating protein |
| AGRP | agouti related neuropeptide |
| AHCYL2 | adenosylhomocysteinase-like 2 |
| AKAP4 | A kinase (PRKA) anchor protein 4 |
| ALOX12 | arachidonate 12-lipoxygenase |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| APOBEC3G | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G |
| ARHGAP26 | Rho GTPase activating protein 26 |
| ATP6V0A2 | ATPase, H+ transporting, lysosomal V0 subunit a2 |
| BIN1 | bridging integrator 1 |
| BMP8B | bone morphogenetic protein 8b |
| C11ORF16 | chromosome 11 open reading frame 16 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CACNG4 | calcium channel, voltage-dependent, gamma subunit 4 |
| CDS1 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 |
| CIB2 | calcium and integrin binding family member 2 |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CLCN4 | chloride channel, voltage-sensitive 4 |
| CRTC1 | CREB regulated transcription coactivator 1 |
| CTIF | CBP80/20-dependent translation initiation factor |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 |
| DHX34 | DEAH (Asp-Glu-Ala-His) box polypeptide 34 |
| DRD5 | dopamine receptor D5 |
| DSC3 | desmocollin 3 |
| EPS8L1 | EPS8-like 1 |
| ERC2-IT1 | ERC2 intronic transcript 1 |
| FAM169A | family with sequence similarity 169, member A |
| FBXO40 | F-box protein 40 |
| FCAR | Fc fragment of IgA receptor |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) |
| GPC3 | glypican 3 |
| GPR153 | G protein-coupled receptor 153 |
| GRIA4 | glutamate receptor, ionotropic, AMPA 4 |
| GYPB | glycophorin B (MNS blood group) |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| IFNA14 | interferon, alpha 14 |
| IMPG2 | interphotoreceptor matrix proteoglycan 2 |
| KIAA0226L | KIAA0226-like |
| KIAA0754 | KIAA0754 |
| LAIR2 | leukocyte-associated immunoglobulin-like receptor 2 |
| LAMB2 | laminin, beta 2 (laminin S) |
| LAMP3 | lysosomal-associated membrane protein 3 |
| LILRB2 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 |
| LOC390998 | ribosomal protein L10 pseudogene |
| LTBP1 | latent transforming growth factor beta binding protein 1 |
| MFSD7 | major facilitator superfamily domain containing 7 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) |
| MMP25 | matrix metallopeptidase 25 |
| MNMIP1 | manchette microtubule inner protein 1 |
| MXRA8 | matrix-remodelling associated 8 |
| NDE1 | nudE neurodevelopment protein 1 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa |
| OGFR | opioid growth factor receptor |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 |
| PCBP4 | poly(rC) binding protein 4 |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 |
| PHF7 | PHD finger protein 7 |
| PIN1P1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1 |
| PML | promyelocytic leukemia |
| PNPLA4 | patatin-like phospholipase domain containing 4 |
| PRKCA | protein kinase C, alpha |
| PSG4 | pregnancy specific beta-1-glycoprotein 4 |
| RAB11FIP3 | RAB11 family interacting protein 3 (class II) |
| RAP1GAP2 | RAP1 GTPase activating protein 2 |
| RASAL2 | RAS protein activator like 2 |
| RBM17 | RNA binding motif protein 17 |
| RBM26 | RNA binding motif protein 26 |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RHBDD3 | rhomboid domain containing 3 |
| RPL10L | ribosomal protein L10-like |
| RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 |
| RTEL1 | regulator of telomere elongation helicase 1 |
| SARS2 | seryl-tRNA synthetase 2, mitochondrial |
| SCAMP5 | secretory carrier membrane protein 5 |
| SDHB | succinate dehydrogenase complex, subunit B, iron sulfur (Ip) |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A |
| SIGLEC1 | sialic acid binding Ig-like lectin 1, sialoadhesin |
| SIT1 | signaling threshold regulating transmembrane adaptor 1 |
| SLC6A13 | solute carrier family 6 (neurotransmitter transporter), member 13 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SULT4A1 | sulfotransferase family 4A, member 1 |
| SYT5 | synaptotagmin V |
| TBXA2R | thromboxane A2 receptor |
| THBS1 | thrombospondin 1 |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TNN | tenascin N |
| TRD | T cell receptor delta locus |
| TTLL5 | tubulin tyrosine ligase-like family member 5 |
| WDTC1 | WD and tetratricopeptide repeats 1 |
| WNT2 | wingless-type MMTV integration site family member 2 |
| ZNF185 | zinc finger protein 185 (LIM domain) |
| ZNF609 | zinc finger protein 609 |
| ZNF639 | zinc finger protein 639 |
| ZNF862 | zinc finger protein 862 |
| Symbol | Name |
|---|---|
| AGO1 | argonaute RISC catalytic component 1 |
| ARHGAP12 | Rho GTPase activating protein 12 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 |
| BCL7C | B-cell CLL/lymphoma 7C |
| C1ORF109 | chromosome 1 open reading frame 109 |
| C2CD2 | C2 calcium-dependent domain containing 2 |
| CCNJ | cyclin J |
| COL15A1 | collagen, type XV, alpha 1 |
| CRYZ | crystallin, zeta (quinone reductase) |
| CTSG | cathepsin G |
| CXCR2 | chemokine (C-X-C motif) receptor 2 |
| CYBA | cytochrome b-245, alpha polypeptide |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| DKK2 | dickkopf WNT signaling pathway inhibitor 2 |
| DNAL4 | dynein, axonemal, light chain 4 |
| DOLK | dolichol kinase |
| ECI1 | enoyl-CoA delta isomerase 1 |
| ENAH | enabled homolog (Drosophila) |
| EOGT | EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase |
| FAM188A | family with sequence similarity 188, member A |
| FLT3 | fms-related tyrosine kinase 3 |
| GAMT | guanidinoacetate N-methyltransferase |
| GIMAP6 | GTPase, IMAP family member 6 |
| GLTP | glycolipid transfer protein |
| GPD1L | glycerol-3-phosphate dehydrogenase 1-like |
| GPR63 | G protein-coupled receptor 63 |
| GSTM3 | glutathione S-transferase mu 3 (brain) |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HDAC9 | histone deacetylase 9 |
| HIST1H2AG | histone cluster 1, H2ag |
| HPSE | heparanase |
| HSPA4L | heat shock 70kDa protein 4-like |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IMPDH1 | IMP (inosine 5'-monophosphate) dehydrogenase 1 |
| INPP5E | inositol polyphosphate-5-phosphatase, 72 kDa |
| KCNA3 | potassium channel, voltage gated shaker related subfamily A, member 3 |
| KCNN2 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 |
| KIF18A | kinesin family member 18A |
| KPNA5 | karyopherin alpha 5 (importin alpha 6) |
| LNPEP | leucyl/cystinyl aminopeptidase |
| LRRK1 | leucine-rich repeat kinase 1 |
| LY75 | lymphocyte antigen 75 |
| MAP1S | microtubule-associated protein 1S |
| MCRS1 | microspherule protein 1 |
| MIS12 | MIS12 kinetochore complex component |
| MMACHC | methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria |
| MRPL28 | mitochondrial ribosomal protein L28 |
| NABP2 | nucleic acid binding protein 2 |
| NEIL3 | nei endonuclease VIII-like 3 (E. coli) |
| NHEJ1 | nonhomologous end-joining factor 1 |
| NUBPL | nucleotide binding protein-like |
| PAQR3 | progestin and adipoQ receptor family member III |
| PARPBP | PARP1 binding protein |
| PCOLCE2 | procollagen C-endopeptidase enhancer 2 |
| PGPEP1 | pyroglutamyl-peptidase I |
| PHACTR1 | phosphatase and actin regulator 1 |
| PHGDH | phosphoglycerate dehydrogenase |
| PMCH | pro-melanin-concentrating hormone |
| PPM1E | protein phosphatase, Mg2+/Mn2+ dependent, 1E |
| PSAT1 | phosphoserine aminotransferase 1 |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RECQL4 | RecQ protein-like 4 |
| RFPL1S | RFPL1 antisense RNA 1 |
| RFXAP | regulatory factor X-associated protein |
| RINT1 | RAD50 interactor 1 |
| RPA4 | replication protein A4, 30kDa |
| RPL39L | ribosomal protein L39-like |
| SAP30L | SAP30-like |
| SCRIB | scribbled planar cell polarity protein |
| SLC16A4 | solute carrier family 16, member 4 |
| SLC25A32 | solute carrier family 25 (mitochondrial folate carrier), member 32 |
| SLC27A5 | solute carrier family 27 (fatty acid transporter), member 5 |
| SLC31A1 | solute carrier family 31 (copper transporter), member 1 |
| SNHG3 | small nucleolar RNA host gene 3 |
| SOAT1 | sterol O-acyltransferase 1 |
| SREK1IP1 | SREK1-interacting protein 1 |
| ST8SIA4 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 |
| TMEM127 | transmembrane protein 127 |
| TMEM184C | transmembrane protein 184C |
| TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase |
| TTC26 | tetratricopeptide repeat domain 26 |
| TTC33 | tetratricopeptide repeat domain 33 |
| TXLNG | taxilin gamma |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| UTP3 | UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae) |
| WDR46 | WD repeat domain 46 |
| WWC3 | WWC family member 3 |
| ZBTB10 | zinc finger and BTB domain containing 10 |
| ZBTB24 | zinc finger and BTB domain containing 24 |
| ZDHHC24 | zinc finger, DHHC-type containing 24 |
| ZFAND3 | zinc finger, AN1-type domain 3 |
| ZNF324 | zinc finger protein 324 |
| ZNF529 | zinc finger protein 529 |
| ZNF573 | zinc finger protein 573 |
| ZNRD1-AS1 | ZNRD1 antisense RNA 1 |
