| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the naftopidil-4193 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC6 | ATP-binding cassette, sub-family C (CFTR/MRP), member 6 |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) |
| ACOT11 | acyl-CoA thioesterase 11 |
| AGFG2 | ArfGAP with FG repeats 2 |
| ANKH | ANKH inorganic pyrophosphate transport regulator |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ARR3 | arrestin 3, retinal (X-arrestin) |
| ATP6V1C1 | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 |
| BAGE | B melanoma antigen |
| BATF | basic leucine zipper transcription factor, ATF-like |
| BBC3 | BCL2 binding component 3 |
| BTG2 | BTG family, member 2 |
| C11ORF63 | chromosome 11 open reading frame 63 |
| C1ORF95 | chromosome 1 open reading frame 95 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| C8ORF44 | chromosome 8 open reading frame 44 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CD53 | CD53 molecule |
| CFH | complement factor H |
| CHAT | choline O-acetyltransferase |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CNTN1 | contactin 1 |
| COL14A1 | collagen, type XIV, alpha 1 |
| CORO2B | coronin, actin binding protein, 2B |
| CTAGE1 | cutaneous T-cell lymphoma-associated antigen 1 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP2D6 | cytochrome P450, family 2, subfamily D, polypeptide 6 |
| DES | desmin |
| DMP1 | dentin matrix acidic phosphoprotein 1 |
| DZIP1 | DAZ interacting zinc finger protein 1 |
| EFR3B | EFR3 homolog B (S. cerevisiae) |
| FAM50B | family with sequence similarity 50, member B |
| FBXO22 | F-box protein 22 |
| FLVCR2 | feline leukemia virus subgroup C cellular receptor family, member 2 |
| FMO5 | flavin containing monooxygenase 5 |
| FRK | fyn-related Src family tyrosine kinase |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type |
| GK3P | glycerol kinase 3 pseudogene |
| GRM1 | glutamate receptor, metabotropic 1 |
| HDAC6 | histone deacetylase 6 |
| HOMER3 | homer scaffolding protein 3 |
| HOXB3 | homeobox B3 |
| HSF2BP | heat shock transcription factor 2 binding protein |
| IFFO1 | intermediate filament family orphan 1 |
| ING4 | inhibitor of growth family, member 4 |
| INO80D | INO80 complex subunit D |
| IQCG | IQ motif containing G |
| KCNJ3 | potassium channel, inwardly rectifying subfamily J, member 3 |
| KIAA1109 | KIAA1109 |
| KIF21B | kinesin family member 21B |
| KIF25 | kinesin family member 25 |
| KIR2DL3 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| NEO1 | neogenin 1 |
| NF1 | neurofibromin 1 |
| NPR1 | natriuretic peptide receptor 1 |
| NPY2R | neuropeptide Y receptor Y2 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 |
| NRP2 | neuropilin 2 |
| OR10C1 | olfactory receptor, family 10, subfamily C, member 1 (gene/pseudogene) |
| PAX8 | paired box 8 |
| PGPEP1 | pyroglutamyl-peptidase I |
| PHF7 | PHD finger protein 7 |
| PRKCA | protein kinase C, alpha |
| PRMT2IP | PRMT2 interacting protein |
| PTEN | phosphatase and tensin homolog |
| PTGDR2 | prostaglandin D2 receptor 2 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 |
| QPCTL | glutaminyl-peptide cyclotransferase-like |
| RAB36 | RAB36, member RAS oncogene family |
| RANBP3 | RAN binding protein 3 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 |
| RHEB | Ras homolog enriched in brain |
| RPGRIP1L | RPGRIP1-like |
| RUFY3 | RUN and FYVE domain containing 3 |
| SCAPER | S-phase cyclin A-associated protein in the ER |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 |
| SHC3 | SHC (Src homology 2 domain containing) transforming protein 3 |
| SLC22A14 | solute carrier family 22, member 14 |
| SLC24A1 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| ST3GAL4 | ST3 beta-galactoside alpha-2,3-sialyltransferase 4 |
| ST8SIA1 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 |
| SUPT20H | suppressor of Ty 20 homolog (S. cerevisiae) |
| TDRKH | tudor and KH domain containing |
| TEX13A | testis expressed 13A |
| TK2 | thymidine kinase 2, mitochondrial |
| TLE4 | transducin-like enhancer of split 4 |
| TNIK | TRAF2 and NCK interacting kinase |
| TUBB1 | tubulin, beta 1 class VI |
| VHL | von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase |
| WSB1 | WD repeat and SOCS box containing 1 |
| ZBTB20 | zinc finger and BTB domain containing 20 |
| ZBTB7A | zinc finger and BTB domain containing 7A |
| ZC2HC1C | zinc finger, C2HC-type containing 1C |
| ZMYM5 | zinc finger, MYM-type 5 |
| ZNF219 | zinc finger protein 219 |
| ZNF236 | zinc finger protein 236 |
| ZNF639 | zinc finger protein 639 |
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| ADAM23 | ADAM metallopeptidase domain 23 |
| ADCY6 | adenylate cyclase 6 |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ALS2CL | ALS2 C-terminal like |
| ANKRD2 | ankyrin repeat domain 2 (stretch responsive muscle) |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ARHGEF26 | Rho guanine nucleotide exchange factor (GEF) 26 |
| ARRB2 | arrestin, beta 2 |
| C14ORF105 | chromosome 14 open reading frame 105 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| C8A | complement component 8, alpha polypeptide |
| CAMKMT | calmodulin-lysine N-methyltransferase |
| CAPN15 | calpain 15 |
| CBX8 | chromobox homolog 8 |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CD68 | CD68 molecule |
| CFAP44 | cilia and flagella associated protein 44 |
| CLDN1 | claudin 1 |
| CLTCL1 | clathrin, heavy chain-like 1 |
| CNN1 | calponin 1, basic, smooth muscle |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| DSPP | dentin sialophosphoprotein |
| EBF2 | early B-cell factor 2 |
| EDC4 | enhancer of mRNA decapping 4 |
| EN2 | engrailed homeobox 2 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| FAM110B | family with sequence similarity 110, member B |
| FBXW12 | F-box and WD repeat domain containing 12 |
| FRMPD1 | FERM and PDZ domain containing 1 |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 |
| GIF | gastric intrinsic factor (vitamin B synthesis) |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H3F | histone cluster 1, H3f |
| ICOS | inducible T-cell co-stimulator |
| IFT140 | intraflagellar transport 140 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
| ISYNA1 | inositol-3-phosphate synthase 1 |
| ITGB7 | integrin, beta 7 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KIAA0319L | KIAA0319-like |
| KRT20 | keratin 20, type I |
| LIN7B | lin-7 homolog B (C. elegans) |
| LOC100127972 | uncharacterized LOC100127972 |
| LOC729164 | hCG1732469 |
| LPPR4 | lipid phosphate phosphatase-related protein type 4 |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| MBL1P | mannose-binding lectin (protein A) 1, pseudogene |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MOGS | mannosyl-oligosaccharide glucosidase |
| MTSS1L | metastasis suppressor 1-like |
| MYO15A | myosin XVA |
| NBEAL2 | neurobeachin-like 2 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| NSUN6 | NOP2/Sun domain family, member 6 |
| NXPH4 | neurexophilin 4 |
| ODF2 | outer dense fiber of sperm tails 2 |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| PDE12 | phosphodiesterase 12 |
| PHKG2 | phosphorylase kinase, gamma 2 (testis) |
| PLD3 | phospholipase D family, member 3 |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PVRL2 | poliovirus receptor-related 2 (herpesvirus entry mediator B) |
| RAB3A | RAB3A, member RAS oncogene family |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RGCC | regulator of cell cycle |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| SENP7 | SUMO1/sentrin specific peptidase 7 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SLC9A3 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 |
| SOX21 | SRY (sex determining region Y)-box 21 |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| TBC1D8B | TBC1 domain family, member 8B (with GRAM domain) |
| TCTN2 | tectonic family member 2 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TMPRSS4 | transmembrane protease, serine 4 |
| TRAPPC6A | trafficking protein particle complex 6A |
| TSPAN2 | tetraspanin 2 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| WDR18 | WD repeat domain 18 |
| WNT1 | wingless-type MMTV integration site family, member 1 |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| XAB2 | XPA binding protein 2 |
| ZFHX3 | zinc finger homeobox 3 |
| ZNF358 | zinc finger protein 358 |
| ZNF391 | zinc finger protein 391 |
| ZNF415 | zinc finger protein 415 |
| ZNF442 | zinc finger protein 442 |
| ZNF711 | zinc finger protein 711 |
| ZNF862 | zinc finger protein 862 |
| ZYX | zyxin |
