| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
197 genes differentially expressed following the naftopidil-7331 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAP1 | ArfGAP with dual PH domains 1 |
| ALS2CL | ALS2 C-terminal like |
| ARHGEF4 | Rho guanine nucleotide exchange factor (GEF) 4 |
| ATF3 | activating transcription factor 3 |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CARD10 | caspase recruitment domain family, member 10 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CCDC9 | coiled-coil domain containing 9 |
| CCL22 | chemokine (C-C motif) ligand 22 |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CDC25A | cell division cycle 25A |
| CDK20 | cyclin-dependent kinase 20 |
| CHRNA6 | cholinergic receptor, nicotinic, alpha 6 (neuronal) |
| CLASP2 | cytoplasmic linker associated protein 2 |
| CLSTN3 | calsyntenin 3 |
| CTBP2 | C-terminal binding protein 2 |
| CTSE | cathepsin E |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP2R1 | cytochrome P450, family 2, subfamily R, polypeptide 1 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DIEXF | digestive organ expansion factor homolog (zebrafish) |
| DSC3 | desmocollin 3 |
| DVL2 | dishevelled segment polarity protein 2 |
| EIF1 | eukaryotic translation initiation factor 1 |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| F2R | coagulation factor II (thrombin) receptor |
| FGF6 | fibroblast growth factor 6 |
| FGFR1 | fibroblast growth factor receptor 1 |
| FH | fumarate hydratase |
| GPR37L1 | G protein-coupled receptor 37 like 1 |
| GRIA3 | glutamate receptor, ionotropic, AMPA 3 |
| GSPT1 | G1 to S phase transition 1 |
| HFE | hemochromatosis |
| IFT38 | intraflagellar transport 38 |
| IGL | immunoglobulin lambda locus |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
| INHBE | inhibin, beta E |
| IRS2 | insulin receptor substrate 2 |
| ITGB5 | integrin, beta 5 |
| JADE2 | jade family PHD finger 2 |
| KIAA0368 | KIAA0368 |
| KLHL28 | kelch-like family member 28 |
| LOXL3 | lysyl oxidase-like 3 |
| LRRC20 | leucine rich repeat containing 20 |
| MAGEB2 | melanoma antigen family B2 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MVD | mevalonate (diphospho) decarboxylase |
| MXD4 | MAX dimerization protein 4 |
| MYOF | myoferlin |
| NDRG2 | NDRG family member 2 |
| NDRG3 | NDRG family member 3 |
| NF1 | neurofibromin 1 |
| NKX3-2 | NK3 homeobox 2 |
| NPY4R | neuropeptide Y receptor Y4 |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PIN4 | peptidylprolyl cis/trans isomerase, NIMA-interacting 4 |
| PLIN2 | perilipin 2 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PPP5C | protein phosphatase 5, catalytic subunit |
| PRODH | proline dehydrogenase (oxidase) 1 |
| PTPN2 | protein tyrosine phosphatase, non-receptor type 2 |
| PVRL1 | poliovirus receptor-related 1 (herpesvirus entry mediator C) |
| RCAN1 | regulator of calcineurin 1 |
| RECK | reversion-inducing-cysteine-rich protein with kazal motifs |
| RGS2 | regulator of G-protein signaling 2 |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| S100A8 | S100 calcium binding protein A8 |
| S100A9 | S100 calcium binding protein A9 |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) |
| SH3BP2 | SH3-domain binding protein 2 |
| SIRT5 | sirtuin 5 |
| SIX2 | SIX homeobox 2 |
| SLA | Src-like-adaptor |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SOX15 | SRY (sex determining region Y)-box 15 |
| SPRY2 | sprouty homolog 2 (Drosophila) |
| SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 |
| SSPN | sarcospan |
| ST20 | suppressor of tumorigenicity 20 |
| ST8SIA3 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 |
| STEAP4 | STEAP family member 4 |
| TBC1D30 | TBC1 domain family, member 30 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) |
| TLDC1 | TBC/LysM-associated domain containing 1 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) |
| TMOD1 | tropomodulin 1 |
| TMPRSS2 | transmembrane protease, serine 2 |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TTC9 | tetratricopeptide repeat domain 9 |
| TYRP1 | tyrosinase-related protein 1 |
| USF2 | upstream transcription factor 2, c-fos interacting |
| USP2 | ubiquitin specific peptidase 2 |
| VPS9D1 | VPS9 domain containing 1 |
| WWP2 | WW domain containing E3 ubiquitin protein ligase 2 |
| Symbol | Name |
|---|---|
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ALPK1 | alpha-kinase 1 |
| ANO10 | anoctamin 10 |
| ANXA2P3 | annexin A2 pseudogene 3 |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| BACE1 | beta-site APP-cleaving enzyme 1 |
| C14ORF93 | chromosome 14 open reading frame 93 |
| CAPN15 | calpain 15 |
| CBX7 | chromobox homolog 7 |
| CBX8 | chromobox homolog 8 |
| CCNO | cyclin O |
| CFD | complement factor D (adipsin) |
| CLDN15 | claudin 15 |
| CORO1A | coronin, actin binding protein, 1A |
| CRBN | cereblon |
| CYP2J2 | cytochrome P450, family 2, subfamily J, polypeptide 2 |
| DCAF13 | DDB1 and CUL4 associated factor 13 |
| DNAL4 | dynein, axonemal, light chain 4 |
| DNM1 | dynamin 1 |
| EAF2 | ELL associated factor 2 |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| ENO2 | enolase 2 (gamma, neuronal) |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| ERCC4 | excision repair cross-complementation group 4 |
| ESRP2 | epithelial splicing regulatory protein 2 |
| ETAA1 | Ewing tumor-associated antigen 1 |
| FANCC | Fanconi anemia, complementation group C |
| FANCE | Fanconi anemia, complementation group E |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FBXO31 | F-box protein 31 |
| FLJ11710 | uncharacterized protein FLJ11710 |
| FLT4 | fms-related tyrosine kinase 4 |
| FYCO1 | FYVE and coiled-coil domain containing 1 |
| GDAP1 | ganglioside induced differentiation associated protein 1 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 |
| GIT2 | G protein-coupled receptor kinase interacting ArfGAP 2 |
| GNL1 | guanine nucleotide binding protein-like 1 |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| HIST1H2BC | histone cluster 1, H2bc |
| IL17RA | interleukin 17 receptor A |
| JUNB | jun B proto-oncogene |
| KIAA0895 | KIAA0895 |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 |
| LYPD1 | LY6/PLAUR domain containing 1 |
| MANBA | mannosidase, beta A, lysosomal |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| MATK | megakaryocyte-associated tyrosine kinase |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MOSPD3 | motile sperm domain containing 3 |
| MTERF4 | mitochondrial transcription termination factor 4 |
| NCS1 | neuronal calcium sensor 1 |
| NEK11 | NIMA-related kinase 11 |
| NRSN2 | neurensin 2 |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| ONECUT2 | one cut homeobox 2 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PCDHB8 | protocadherin beta 8 |
| PDZRN3 | PDZ domain containing ring finger 3 |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 |
| PTPN9 | protein tyrosine phosphatase, non-receptor type 9 |
| RAB33B | RAB33B, member RAS oncogene family |
| RAB3A | RAB3A, member RAS oncogene family |
| RBM41 | RNA binding motif protein 41 |
| RECQL4 | RecQ protein-like 4 |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| RPGR | retinitis pigmentosa GTPase regulator |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| RUFY2 | RUN and FYVE domain containing 2 |
| SCMH1 | sex comb on midleg homolog 1 (Drosophila) |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC46A3 | solute carrier family 46, member 3 |
| SMARCAL1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 |
| SP1 | Sp1 transcription factor |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) |
| TGFB3 | transforming growth factor, beta 3 |
| TMEM121 | transmembrane protein 121 |
| TMEM2 | transmembrane protein 2 |
| TRABD | TraB domain containing |
| TRIM25 | tripartite motif containing 25 |
| TSSC4 | tumor suppressing subtransferable candidate 4 |
| TUBG2 | tubulin, gamma 2 |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| VEGFB | vascular endothelial growth factor B |
| VEGFC | vascular endothelial growth factor C |
| WWC2 | WW and C2 domain containing 2 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| ZNF254 | zinc finger protein 254 |
| ZNF675 | zinc finger protein 675 |
