| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the nalbuphine-7177 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ADAM10 | ADAM metallopeptidase domain 10 |
| ADGRA2 | adhesion G protein-coupled receptor A2 |
| AK2 | adenylate kinase 2 |
| AKAP7 | A kinase (PRKA) anchor protein 7 |
| AKAP9 | A kinase (PRKA) anchor protein 9 |
| ALDH6A1 | aldehyde dehydrogenase 6 family, member A1 |
| AP4E1 | adaptor-related protein complex 4, epsilon 1 subunit |
| APBA1 | amyloid beta (A4) precursor protein-binding, family A, member 1 |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| AQP3 | aquaporin 3 (Gill blood group) |
| ARPIN | actin-related protein 2/3 complex inhibitor |
| ATXN7L3B | ataxin 7-like 3B |
| BCL3 | B-cell CLL/lymphoma 3 |
| BRF2 | BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit |
| C19ORF73 | chromosome 19 open reading frame 73 |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CDK3 | cyclin-dependent kinase 3 |
| CFAP69 | cilia and flagella associated protein 69 |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| CRAT | carnitine O-acetyltransferase |
| CREBZF | CREB/ATF bZIP transcription factor |
| CRKL | v-crk avian sarcoma virus CT10 oncogene homolog-like |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) |
| CYP1A2 | cytochrome P450, family 1, subfamily A, polypeptide 2 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DSCAM | Down syndrome cell adhesion molecule |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 |
| ESR1 | estrogen receptor 1 |
| ETV7 | ets variant 7 |
| FBLN1 | fibulin 1 |
| FBXL2 | F-box and leucine-rich repeat protein 2 |
| FLT4 | fms-related tyrosine kinase 4 |
| FN1 | fibronectin 1 |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
| GSK3A | glycogen synthase kinase 3 alpha |
| HCRP1 | hepatocellular carcinoma-related HCRP1 |
| HDAC11 | histone deacetylase 11 |
| HEXA | hexosaminidase A (alpha polypeptide) |
| HFE | hemochromatosis |
| HIST1H2BC | histone cluster 1, H2bc |
| HIST1H2BJ | histone cluster 1, H2bj |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IQCC | IQ motif containing C |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
| KRT19P2 | keratin 19 pseudogene 2 |
| LOC257152 | uncharacterized LOC257152 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MBD3 | methyl-CpG binding domain protein 3 |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MBNL3 | muscleblind-like splicing regulator 3 |
| METTL7A | methyltransferase like 7A |
| MFN2 | mitofusin 2 |
| MSMB | microseminoprotein, beta- |
| MTCP1 | mature T-cell proliferation 1 |
| NADK | NAD kinase |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NF2 | neurofibromin 2 (merlin) |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| OVOL2 | ovo-like zinc finger 2 |
| PCM1 | pericentriolar material 1 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| PMFBP1 | polyamine modulated factor 1 binding protein 1 |
| POM121L2 | POM121 transmembrane nucleoporin-like 2 |
| PRDM9 | PR domain containing 9 |
| PTBP3 | polypyrimidine tract binding protein 3 |
| QKI | QKI, KH domain containing, RNA binding |
| RABGAP1 | RAB GTPase activating protein 1 |
| RNF39 | ring finger protein 39 |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 |
| RPL7 | ribosomal protein L7 |
| RTEL1 | regulator of telomere elongation helicase 1 |
| RYK | receptor-like tyrosine kinase |
| SAP30 | Sin3A-associated protein, 30kDa |
| SDC2 | syndecan 2 |
| SEMA4G | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G |
| SKIL | SKI-like proto-oncogene |
| SMC1A | structural maintenance of chromosomes 1A |
| SNX13 | sorting nexin 13 |
| SPOCK3 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| THBD | thrombomodulin |
| TMC7 | transmembrane channel-like 7 |
| TMEM120B | transmembrane protein 120B |
| TNFAIP1 | tumor necrosis factor, alpha-induced protein 1 (endothelial) |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b |
| TPD52 | tumor protein D52 |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| WSB1 | WD repeat and SOCS box containing 1 |
| ZDHHC17 | zinc finger, DHHC-type containing 17 |
| ZFP64 | ZFP64 zinc finger protein |
| ZNF675 | zinc finger protein 675 |
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit |
| ARMC7 | armadillo repeat containing 7 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| ATF3 | activating transcription factor 3 |
| AXIN1 | axin 1 |
| BATF | basic leucine zipper transcription factor, ATF-like |
| C17ORF62 | chromosome 17 open reading frame 62 |
| C21ORF91 | chromosome 21 open reading frame 91 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CEP85 | centrosomal protein 85kDa |
| CHKB | choline kinase beta |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| COL9A2 | collagen, type IX, alpha 2 |
| CTDSP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 |
| CTSK | cathepsin K |
| CWC25 | CWC25 spliceosome-associated protein homolog (S. cerevisiae) |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DEAF1 | DEAF1 transcription factor |
| DENND4B | DENN/MADD domain containing 4B |
| DGKD | diacylglycerol kinase, delta 130kDa |
| DHX38 | DEAH (Asp-Glu-Ala-His) box polypeptide 38 |
| EAF2 | ELL associated factor 2 |
| EHD3 | EH-domain containing 3 |
| EPHA2 | EPH receptor A2 |
| FAM189B | family with sequence similarity 189, member B |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FOSL1 | FOS-like antigen 1 |
| FOXJ2 | forkhead box J2 |
| FZD2 | frizzled class receptor 2 |
| GAREM | GRB2 associated, regulator of MAPK1 |
| GPRC5C | G protein-coupled receptor, class C, group 5, member C |
| GRWD1 | glutamate-rich WD repeat containing 1 |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| HIST1H2AI | histone cluster 1, H2ai |
| HOXC13 | homeobox C13 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
| IMPACT | impact RWD domain protein |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| LIMA1 | LIM domain and actin binding 1 |
| LOC100272216 | uncharacterized LOC100272216 |
| LRP5 | low density lipoprotein receptor-related protein 5 |
| LRRC49 | leucine rich repeat containing 49 |
| LY6D | lymphocyte antigen 6 complex, locus D |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| MAMLD1 | mastermind-like domain containing 1 |
| MANBA | mannosidase, beta A, lysosomal |
| MDC1 | mediator of DNA-damage checkpoint 1 |
| MED24 | mediator complex subunit 24 |
| MORC3 | MORC family CW-type zinc finger 3 |
| MPP6 | membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase |
| MXD3 | MAX dimerization protein 3 |
| NCAM2 | neural cell adhesion molecule 2 |
| NDRG1 | N-myc downstream regulated 1 |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| PISD | phosphatidylserine decarboxylase |
| PLA2G15 | phospholipase A2, group XV |
| POR | P450 (cytochrome) oxidoreductase |
| PSTPIP2 | proline-serine-threonine phosphatase interacting protein 2 |
| PTTG3P | pituitary tumor-transforming 3, pseudogene |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RNF123 | ring finger protein 123 |
| RNF31 | ring finger protein 31 |
| RUFY2 | RUN and FYVE domain containing 2 |
| SAV1 | salvador family WW domain containing protein 1 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC26A6 | solute carrier family 26 (anion exchanger), member 6 |
| SLC29A2 | solute carrier family 29 (equilibrative nucleoside transporter), member 2 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SMARCAL1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SNHG3 | small nucleolar RNA host gene 3 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 |
| STRN4 | striatin, calmodulin binding protein 4 |
| TESK1 | testis-specific kinase 1 |
| THBS3 | thrombospondin 3 |
| THOP1 | thimet oligopeptidase 1 |
| TLN1 | talin 1 |
| TMEM127 | transmembrane protein 127 |
| TMEM254 | transmembrane protein 254 |
| TNS2 | tensin 2 |
| TRAIP | TRAF interacting protein |
| TTC30A | tetratricopeptide repeat domain 30A |
| UBIAD1 | UbiA prenyltransferase domain containing 1 |
| UBXN6 | UBX domain protein 6 |
| USP36 | ubiquitin specific peptidase 36 |
| VAV1 | vav 1 guanine nucleotide exchange factor |
| WDR60 | WD repeat domain 60 |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZDHHC18 | zinc finger, DHHC-type containing 18 |
| ZNF219 | zinc finger protein 219 |
| ZNF813 | zinc finger protein 813 |
