Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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193 genes differentially expressed following the nalidixic acid-7367 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ADAM5 | ADAM metallopeptidase domain 5 (pseudogene) |
ADGRG1 | adhesion G protein-coupled receptor G1 |
ANGEL2 | angel homolog 2 (Drosophila) |
ANKRD6 | ankyrin repeat domain 6 |
ARAP1 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 |
ASAP3 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 |
CA9 | carbonic anhydrase IX |
CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
CACNB3 | calcium channel, voltage-dependent, beta 3 subunit |
CAMSAP1 | calmodulin regulated spectrin-associated protein 1 |
CASKIN2 | CASK interacting protein 2 |
CCNT2 | cyclin T2 |
CDHR2 | cadherin-related family member 2 |
CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
CHST5 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 |
CIB2 | calcium and integrin binding family member 2 |
CLCN6 | chloride channel, voltage-sensitive 6 |
CLDN11 | claudin 11 |
CNNM1 | cyclin and CBS domain divalent metal cation transport mediator 1 |
COL8A1 | collagen, type VIII, alpha 1 |
CSRNP3 | cysteine-serine-rich nuclear protein 3 |
CYP2J2 | cytochrome P450, family 2, subfamily J, polypeptide 2 |
CYSLTR1 | cysteinyl leukotriene receptor 1 |
DOC2B | double C2-like domains, beta |
DPYS | dihydropyrimidinase |
DRD2 | dopamine receptor D2 |
EDRF1 | erythroid differentiation regulatory factor 1 |
ELK4 | ELK4, ETS-domain protein (SRF accessory protein 1) |
ESR1 | estrogen receptor 1 |
ETV1 | ets variant 1 |
ETV5 | ets variant 5 |
EXOC6B | exocyst complex component 6B |
FAM120C | family with sequence similarity 120C |
FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 |
FGF1 | fibroblast growth factor 1 (acidic) |
FN1 | fibronectin 1 |
FURIN | furin (paired basic amino acid cleaving enzyme) |
G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 |
GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
GRM1 | glutamate receptor, metabotropic 1 |
GZMK | granzyme K (granzyme 3; tryptase II) |
HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
IL15 | interleukin 15 |
KCNA5 | potassium channel, voltage gated shaker related subfamily A, member 5 |
KRTAP1-3 | keratin associated protein 1-3 |
KYNU | kynureninase |
LARP4B | La ribonucleoprotein domain family, member 4B |
LCT | lactase |
LEF1 | lymphoid enhancer-binding factor 1 |
LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
MGAT3 | mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase |
MYO5A | myosin VA (heavy chain 12, myoxin) |
NAGLU | N-acetylglucosaminidase, alpha |
NLGN1 | neuroligin 1 |
NPHS2 | nephrosis 2, idiopathic, steroid-resistant (podocin) |
OR12D3 | olfactory receptor, family 12, subfamily D, member 3 |
OVGP1 | oviductal glycoprotein 1, 120kDa |
PAPOLA | poly(A) polymerase alpha |
PDE11A | phosphodiesterase 11A |
PDGFB | platelet-derived growth factor beta polypeptide |
PER3 | period circadian clock 3 |
PFKL | phosphofructokinase, liver |
PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
PODNL1 | podocan-like 1 |
POU5F1B | POU class 5 homeobox 1B |
PPARD | peroxisome proliferator-activated receptor delta |
PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
PRDM2 | PR domain containing 2, with ZNF domain |
PRKACG | protein kinase, cAMP-dependent, catalytic, gamma |
PTPRCAP | protein tyrosine phosphatase, receptor type, C-associated protein |
PXMP4 | peroxisomal membrane protein 4, 24kDa |
RGS12 | regulator of G-protein signaling 12 |
RUNDC3B | RUN domain containing 3B |
RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) |
S1PR1 | sphingosine-1-phosphate receptor 1 |
SCG2 | secretogranin II |
SCNN1D | sodium channel, non voltage gated 1 delta subunit |
SEC14L4 | SEC14-like 4 (S. cerevisiae) |
SLC1A7 | solute carrier family 1 (glutamate transporter), member 7 |
SMARCD1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 |
SNX13 | sorting nexin 13 |
SPTAN1 | spectrin, alpha, non-erythrocytic 1 |
STK24 | serine/threonine kinase 24 |
SUGP1 | SURP and G patch domain containing 1 |
TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 |
TAOK3 | TAO kinase 3 |
TENM4 | teneurin transmembrane protein 4 |
TG | thyroglobulin |
TRPC3 | transient receptor potential cation channel, subfamily C, member 3 |
TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
TXNRD3 | thioredoxin reductase 3 |
UGT2B15 | UDP glucuronosyltransferase 2 family, polypeptide B15 |
VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) |
ZNF222 | zinc finger protein 222 |
ZNF276 | zinc finger protein 276 |
ZNF358 | zinc finger protein 358 |
ZNF391 | zinc finger protein 391 |
ZNF862 | zinc finger protein 862 |
Symbol | Name |
---|---|
AAAS | achalasia, adrenocortical insufficiency, alacrimia |
AGBL5 | ATP/GTP binding protein-like 5 |
ANG | angiogenin, ribonuclease, RNase A family, 5 |
ASB7 | ankyrin repeat and SOCS box containing 7 |
BCKDHA | branched chain keto acid dehydrogenase E1, alpha polypeptide |
BCL9 | B-cell CLL/lymphoma 9 |
BSPRY | B-box and SPRY domain containing |
C1ORF159 | chromosome 1 open reading frame 159 |
C4ORF19 | chromosome 4 open reading frame 19 |
C7ORF43 | chromosome 7 open reading frame 43 |
CABYR | calcium binding tyrosine-(Y)-phosphorylation regulated |
CCDC106 | coiled-coil domain containing 106 |
CCDC68 | coiled-coil domain containing 68 |
CDH7 | cadherin 7, type 2 |
CENPJ | centromere protein J |
CENPO | centromere protein O |
CENPT | centromere protein T |
CEP112 | centrosomal protein 112kDa |
CINP | cyclin-dependent kinase 2 interacting protein |
CLEC10A | C-type lectin domain family 10, member A |
CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
CYP26B1 | cytochrome P450, family 26, subfamily B, polypeptide 1 |
CYP2R1 | cytochrome P450, family 2, subfamily R, polypeptide 1 |
DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
DHX57 | DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 |
ELP6 | elongator acetyltransferase complex subunit 6 |
ENO2 | enolase 2 (gamma, neuronal) |
FAM178A | family with sequence similarity 178, member A |
FBXL4 | F-box and leucine-rich repeat protein 4 |
FBXW12 | F-box and WD repeat domain containing 12 |
GLDC | glycine dehydrogenase (decarboxylating) |
HDAC4 | histone deacetylase 4 |
HIST1H2AJ | histone cluster 1, H2aj |
HIST1H2AM | histone cluster 1, H2am |
HIST1H3B | histone cluster 1, H3b |
ICK | intestinal cell (MAK-like) kinase |
IMPAD1 | inositol monophosphatase domain containing 1 |
IQCG | IQ motif containing G |
KBTBD4 | kelch repeat and BTB (POZ) domain containing 4 |
KLF7 | Kruppel-like factor 7 (ubiquitous) |
LRP5L | low density lipoprotein receptor-related protein 5-like |
MAP3K6 | mitogen-activated protein kinase kinase kinase 6 |
MFGE8 | milk fat globule-EGF factor 8 protein |
MITF | microphthalmia-associated transcription factor |
MOXD1 | monooxygenase, DBH-like 1 |
MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric |
NOL12 | nucleolar protein 12 |
NOTCH1 | notch 1 |
NR1H3 | nuclear receptor subfamily 1, group H, member 3 |
NT5M | 5',3'-nucleotidase, mitochondrial |
NUBPL | nucleotide binding protein-like |
NUDT11 | nudix (nucleoside diphosphate linked moiety X)-type motif 11 |
OSMR | oncostatin M receptor |
P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 |
P3H4 | prolyl 3-hydroxylase family member 4 (non-enzymatic) |
PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
PLCD1 | phospholipase C, delta 1 |
PPP1R13B | protein phosphatase 1, regulatory subunit 13B |
PRICKLE3 | prickle homolog 3 (Drosophila) |
RASA2 | RAS p21 protein activator 2 |
SCRN3 | secernin 3 |
SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 |
SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 |
SLC25A40 | solute carrier family 25, member 40 |
SLITRK5 | SLIT and NTRK-like family, member 5 |
SMG9 | SMG9 nonsense mediated mRNA decay factor |
SNHG3 | small nucleolar RNA host gene 3 |
SNIP1 | Smad nuclear interacting protein 1 |
ST20 | suppressor of tumorigenicity 20 |
STAC | SH3 and cysteine rich domain |
STAG3 | stromal antigen 3 |
STARD5 | StAR-related lipid transfer (START) domain containing 5 |
SUGCT | succinyl-CoA:glutarate-CoA transferase |
TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa |
TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
TLR2 | toll-like receptor 2 |
TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
TMC7 | transmembrane channel-like 7 |
TMEM132A | transmembrane protein 132A |
TMEM57 | transmembrane protein 57 |
TMEM62 | transmembrane protein 62 |
TNNI3 | troponin I type 3 (cardiac) |
TNRC6B | trinucleotide repeat containing 6B |
TTLL7 | tubulin tyrosine ligase-like family member 7 |
USP6 | ubiquitin specific peptidase 6 |
WDR19 | WD repeat domain 19 |
WWC2 | WW and C2 domain containing 2 |
XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
ZNF112 | zinc finger protein 112 |
ZNF189 | zinc finger protein 189 |
ZNF84 | zinc finger protein 84 |
ZNHIT2 | zinc finger, HIT-type containing 2 |