nalidixic-acid Gene Set
Genes
15 genes differentially expressed following the nalidixic-acid small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
RRP8
|
ribosomal RNA processing 8, methyltransferase, homolog (yeast)
|
3.95813
|
|
CNOT4
|
CCR4-NOT transcription complex, subunit 4
|
3.67021
|
|
HMG20B
|
high mobility group 20B
|
3.62779
|
|
MALT1
|
MALT1 paracaspase
|
3.43388
|
|
HS2ST1
|
heparan sulfate 2-O-sulfotransferase 1
|
3.27044
|
|
FRS2
|
fibroblast growth factor receptor substrate 2
|
3.09519
|
|
PPT1
|
palmitoyl-protein thioesterase 1
|
3.0093
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
NFKBIB
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
|
-4.85653
|
|
SLC22A11
|
solute carrier family 22 (organic anion/urate transporter), member 11
|
-3.44854
|
|
VPS28
|
vacuolar protein sorting 28 homolog (S. cerevisiae)
|
-3.16884
|
|
SLC1A3
|
solute carrier family 1 (glial high affinity glutamate transporter), member 3
|
-3.12073
|
|
CASP10
|
caspase 10, apoptosis-related cysteine peptidase
|
-3.08914
|
|
RECQL5
|
RecQ protein-like 5
|
-3.06741
|
|
HABP4
|
hyaluronan binding protein 4
|
-3.03851
|
|
SLC10A2
|
solute carrier family 10 (sodium/bile acid cotransporter), member 2
|
-3.01761
|