naloxone-1506 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

197 genes differentially expressed following the naloxone-1506 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ACTL8 actin-like 8
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit
APOC1 apolipoprotein C-I
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARL4C ADP-ribosylation factor-like 4C
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ASB1 ankyrin repeat and SOCS box containing 1
AUTS2 autism susceptibility candidate 2
BBS9 Bardet-Biedl syndrome 9
C1QB complement component 1, q subcomponent, B chain
CCNK cyclin K
CD37 CD37 molecule
CD82 CD82 molecule
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CEP164 centrosomal protein 164kDa
CEP290 centrosomal protein 290kDa
CERS4 ceramide synthase 4
CIDEB cell death-inducing DFFA-like effector b
CSF1R colony stimulating factor 1 receptor
CTBP2 C-terminal binding protein 2
CYB5A cytochrome b5 type A (microsomal)
CYHR1 cysteine/histidine-rich 1
DCAKD dephospho-CoA kinase domain containing
DLK2 delta-like 2 homolog (Drosophila)
DOCK5 dedicator of cytokinesis 5
DPF1 D4, zinc and double PHD fingers family 1
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EFNB3 ephrin-B3
EGR2 early growth response 2
EMID1 EMI domain containing 1
ENC1 ectodermal-neural cortex 1 (with BTB domain)
EPHX2 epoxide hydrolase 2, cytoplasmic
FAM46C family with sequence similarity 46, member C
FOXG1 forkhead box G1
GJA9 gap junction protein, alpha 9, 59kDa
GM2A GM2 ganglioside activator
GRK6 G protein-coupled receptor kinase 6
HFE hemochromatosis
HIC2 hypermethylated in cancer 2
HIST1H4D histone cluster 1, H4d
HLA-F major histocompatibility complex, class I, F
HPCAL4 hippocalcin like 4
HR hair growth associated
IL22 interleukin 22
IRF4 interferon regulatory factor 4
ISG20 interferon stimulated exonuclease gene 20kDa
JADE2 jade family PHD finger 2
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
LOXL3 lysyl oxidase-like 3
LPXN leupaxin
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
MEGF6 multiple EGF-like-domains 6
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MSX2 msh homeobox 2
MTA1 metastasis associated 1
MTAP methylthioadenosine phosphorylase
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1)
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa
NEK9 NIMA-related kinase 9
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NOX1 NADPH oxidase 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
PCDH11Y protocadherin 11 Y-linked
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PMS2P2 postmeiotic segregation increased 2 pseudogene 2
POMT2 protein-O-mannosyltransferase 2
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PTGDS prostaglandin D2 synthase 21kDa (brain)
RBMS2 RNA binding motif, single stranded interacting protein 2
REST RE1-silencing transcription factor
RHOH ras homolog family member H
RIMS3 regulating synaptic membrane exocytosis 3
RIN1 Ras and Rab interactor 1
RUNX1 runt-related transcription factor 1
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SLA Src-like-adaptor
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLCO1C1 solute carrier organic anion transporter family, member 1C1
SPTBN1 spectrin, beta, non-erythrocytic 1
STS steroid sulfatase (microsomal), isozyme S
SYNJ2 synaptojanin 2
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TBC1D19 TBC1 domain family, member 19
TEX15 testis expressed 15
TIMELESS timeless circadian clock
TSC22D2 TSC22 domain family, member 2
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae)
ZDHHC14 zinc finger, DHHC-type containing 14
ZFP64 ZFP64 zinc finger protein
ZMYM2 zinc finger, MYM-type 2
ZNF79 zinc finger protein 79

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ABHD14A abhydrolase domain containing 14A
ALG12 ALG12, alpha-1,6-mannosyltransferase
ARC activity-regulated cytoskeleton-associated protein
ARRB1 arrestin, beta 1
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BCOR BCL6 corepressor
C1ORF105 chromosome 1 open reading frame 105
C22ORF29 chromosome 22 open reading frame 29
C5AR2 complement component 5a receptor 2
CBX4 chromobox homolog 4
CCDC85C coiled-coil domain containing 85C
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CHML choroideremia-like (Rab escort protein 2)
CHST10 carbohydrate sulfotransferase 10
CLCN6 chloride channel, voltage-sensitive 6
CNGB3 cyclic nucleotide gated channel beta 3
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DENND4A DENN/MADD domain containing 4A
DOC2A double C2-like domains, alpha
EPB41L5 erythrocyte membrane protein band 4.1 like 5
ETNK2 ethanolamine kinase 2
F2R coagulation factor II (thrombin) receptor
FGD1 FYVE, RhoGEF and PH domain containing 1
GLCE glucuronic acid epimerase
GMPR guanosine monophosphate reductase
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GPRASP1 G protein-coupled receptor associated sorting protein 1
GRPR gastrin-releasing peptide receptor
GSTA4 glutathione S-transferase alpha 4
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HLA-J major histocompatibility complex, class I, J (pseudogene)
HOXC13 homeobox C13
HPN hepsin
IFT140 intraflagellar transport 140
IGFBP6 insulin-like growth factor binding protein 6
IP6K1 inositol hexakisphosphate kinase 1
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
KLF3 Kruppel-like factor 3 (basic)
LOC100272216 uncharacterized LOC100272216
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LRP6 low density lipoprotein receptor-related protein 6
MAGEF1 melanoma antigen family F1
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MAPKBP1 mitogen-activated protein kinase binding protein 1
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MMP2 matrix metallopeptidase 2
MON1B MON1 secretory trafficking family member B
MYBBP1A MYB binding protein (P160) 1a
NDE1 nudE neurodevelopment protein 1
NPIPB15 nuclear pore complex interacting protein family, member B15
NT5DC3 5'-nucleotidase domain containing 3
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
P3H1 prolyl 3-hydroxylase 1
PADI2 peptidyl arginine deiminase, type II
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PLEKHO2 pleckstrin homology domain containing, family O member 2
PRICKLE3 prickle homolog 3 (Drosophila)
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PTPRE protein tyrosine phosphatase, receptor type, E
PTPRU protein tyrosine phosphatase, receptor type, U
RAB30 RAB30, member RAS oncogene family
RHBDD3 rhomboid domain containing 3
RNF39 ring finger protein 39
RPH3AL rabphilin 3A-like (without C2 domains)
SCMH1 sex comb on midleg homolog 1 (Drosophila)
SIRT6 sirtuin 6
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SNAI2 snail family zinc finger 2
SPINK5 serine peptidase inhibitor, Kazal type 5
STBD1 starch binding domain 1
STRA6 stimulated by retinoic acid 6
SULT4A1 sulfotransferase family 4A, member 1
TESC tescalcin
TEX40 testis expressed 40
THBS3 thrombospondin 3
TMC5 transmembrane channel-like 5
TMPRSS3 transmembrane protease, serine 3
TRIM5 tripartite motif containing 5
TRIM66 tripartite motif containing 66
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae)
UBQLN4 ubiquilin 4
UNC93B1 unc-93 homolog B1 (C. elegans)
VAX2 ventral anterior homeobox 2
XYLT2 xylosyltransferase II
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZBTB22 zinc finger and BTB domain containing 22
ZNF253 zinc finger protein 253
ZNF34 zinc finger protein 34
ZNF76 zinc finger protein 76
ZNF767P zinc finger family member 767, pseudogene