| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the naloxone-1506 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA12 | ATP-binding cassette, sub-family A (ABC1), member 12 |
| ACTL8 | actin-like 8 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent |
| AP5Z1 | adaptor-related protein complex 5, zeta 1 subunit |
| APOC1 | apolipoprotein C-I |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ARL4C | ADP-ribosylation factor-like 4C |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| ASB1 | ankyrin repeat and SOCS box containing 1 |
| AUTS2 | autism susceptibility candidate 2 |
| BBS9 | Bardet-Biedl syndrome 9 |
| C1QB | complement component 1, q subcomponent, B chain |
| CCNK | cyclin K |
| CD37 | CD37 molecule |
| CD82 | CD82 molecule |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 |
| CEP164 | centrosomal protein 164kDa |
| CEP290 | centrosomal protein 290kDa |
| CERS4 | ceramide synthase 4 |
| CIDEB | cell death-inducing DFFA-like effector b |
| CSF1R | colony stimulating factor 1 receptor |
| CTBP2 | C-terminal binding protein 2 |
| CYB5A | cytochrome b5 type A (microsomal) |
| CYHR1 | cysteine/histidine-rich 1 |
| DCAKD | dephospho-CoA kinase domain containing |
| DLK2 | delta-like 2 homolog (Drosophila) |
| DOCK5 | dedicator of cytokinesis 5 |
| DPF1 | D4, zinc and double PHD fingers family 1 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| EFNB3 | ephrin-B3 |
| EGR2 | early growth response 2 |
| EMID1 | EMI domain containing 1 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) |
| EPHX2 | epoxide hydrolase 2, cytoplasmic |
| FAM46C | family with sequence similarity 46, member C |
| FOXG1 | forkhead box G1 |
| GJA9 | gap junction protein, alpha 9, 59kDa |
| GM2A | GM2 ganglioside activator |
| GRK6 | G protein-coupled receptor kinase 6 |
| HFE | hemochromatosis |
| HIC2 | hypermethylated in cancer 2 |
| HIST1H4D | histone cluster 1, H4d |
| HLA-F | major histocompatibility complex, class I, F |
| HPCAL4 | hippocalcin like 4 |
| HR | hair growth associated |
| IL22 | interleukin 22 |
| IRF4 | interferon regulatory factor 4 |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| JADE2 | jade family PHD finger 2 |
| KAZALD1 | Kazal-type serine peptidase inhibitor domain 1 |
| LOXL3 | lysyl oxidase-like 3 |
| LPXN | leupaxin |
| MC2R | melanocortin 2 receptor (adrenocorticotropic hormone) |
| MEGF6 | multiple EGF-like-domains 6 |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MSX2 | msh homeobox 2 |
| MTA1 | metastasis associated 1 |
| MTAP | methylthioadenosine phosphorylase |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) |
| NDUFB7 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa |
| NEK9 | NIMA-related kinase 9 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NOX1 | NADPH oxidase 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| PCDH11Y | protocadherin 11 Y-linked |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PMS2P2 | postmeiotic segregation increased 2 pseudogene 2 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| RBMS2 | RNA binding motif, single stranded interacting protein 2 |
| REST | RE1-silencing transcription factor |
| RHOH | ras homolog family member H |
| RIMS3 | regulating synaptic membrane exocytosis 3 |
| RIN1 | Ras and Rab interactor 1 |
| RUNX1 | runt-related transcription factor 1 |
| SEMA6A | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A |
| SLA | Src-like-adaptor |
| SLC1A2 | solute carrier family 1 (glial high affinity glutamate transporter), member 2 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLCO1C1 | solute carrier organic anion transporter family, member 1C1 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 |
| STS | steroid sulfatase (microsomal), isozyme S |
| SYNJ2 | synaptojanin 2 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 |
| TBC1D19 | TBC1 domain family, member 19 |
| TEX15 | testis expressed 15 |
| TIMELESS | timeless circadian clock |
| TSC22D2 | TSC22 domain family, member 2 |
| VPS53 | vacuolar protein sorting 53 homolog (S. cerevisiae) |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZFP64 | ZFP64 zinc finger protein |
| ZMYM2 | zinc finger, MYM-type 2 |
| ZNF79 | zinc finger protein 79 |
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| ABHD14A | abhydrolase domain containing 14A |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ARC | activity-regulated cytoskeleton-associated protein |
| ARRB1 | arrestin, beta 1 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| BCOR | BCL6 corepressor |
| C1ORF105 | chromosome 1 open reading frame 105 |
| C22ORF29 | chromosome 22 open reading frame 29 |
| C5AR2 | complement component 5a receptor 2 |
| CBX4 | chromobox homolog 4 |
| CCDC85C | coiled-coil domain containing 85C |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CHML | choroideremia-like (Rab escort protein 2) |
| CHST10 | carbohydrate sulfotransferase 10 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CYP20A1 | cytochrome P450, family 20, subfamily A, polypeptide 1 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
| DENND4A | DENN/MADD domain containing 4A |
| DOC2A | double C2-like domains, alpha |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| ETNK2 | ethanolamine kinase 2 |
| F2R | coagulation factor II (thrombin) receptor |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| GLCE | glucuronic acid epimerase |
| GMPR | guanosine monophosphate reductase |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GPRASP1 | G protein-coupled receptor associated sorting protein 1 |
| GRPR | gastrin-releasing peptide receptor |
| GSTA4 | glutathione S-transferase alpha 4 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HLA-J | major histocompatibility complex, class I, J (pseudogene) |
| HOXC13 | homeobox C13 |
| HPN | hepsin |
| IFT140 | intraflagellar transport 140 |
| IGFBP6 | insulin-like growth factor binding protein 6 |
| IP6K1 | inositol hexakisphosphate kinase 1 |
| IPPK | inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| KLF3 | Kruppel-like factor 3 (basic) |
| LOC100272216 | uncharacterized LOC100272216 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 |
| LRP6 | low density lipoprotein receptor-related protein 6 |
| MAGEF1 | melanoma antigen family F1 |
| MAP3K6 | mitogen-activated protein kinase kinase kinase 6 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 |
| MMP2 | matrix metallopeptidase 2 |
| MON1B | MON1 secretory trafficking family member B |
| MYBBP1A | MYB binding protein (P160) 1a |
| NDE1 | nudE neurodevelopment protein 1 |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| P3H1 | prolyl 3-hydroxylase 1 |
| PADI2 | peptidyl arginine deiminase, type II |
| PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PRKAR1B | protein kinase, cAMP-dependent, regulatory, type I, beta |
| PTPRE | protein tyrosine phosphatase, receptor type, E |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| RAB30 | RAB30, member RAS oncogene family |
| RHBDD3 | rhomboid domain containing 3 |
| RNF39 | ring finger protein 39 |
| RPH3AL | rabphilin 3A-like (without C2 domains) |
| SCMH1 | sex comb on midleg homolog 1 (Drosophila) |
| SIRT6 | sirtuin 6 |
| SLC25A20 | solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SNAI2 | snail family zinc finger 2 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| STBD1 | starch binding domain 1 |
| STRA6 | stimulated by retinoic acid 6 |
| SULT4A1 | sulfotransferase family 4A, member 1 |
| TESC | tescalcin |
| TEX40 | testis expressed 40 |
| THBS3 | thrombospondin 3 |
| TMC5 | transmembrane channel-like 5 |
| TMPRSS3 | transmembrane protease, serine 3 |
| TRIM5 | tripartite motif containing 5 |
| TRIM66 | tripartite motif containing 66 |
| TRMT13 | tRNA methyltransferase 13 homolog (S. cerevisiae) |
| UBQLN4 | ubiquilin 4 |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| VAX2 | ventral anterior homeobox 2 |
| XYLT2 | xylosyltransferase II |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZNF253 | zinc finger protein 253 |
| ZNF34 | zinc finger protein 34 |
| ZNF76 | zinc finger protein 76 |
| ZNF767P | zinc finger family member 767, pseudogene |