| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the naloxone-1924 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ACAN | aggrecan |
| ADAM8 | ADAM metallopeptidase domain 8 |
| AFF1 | AF4/FMR2 family, member 1 |
| ANK2 | ankyrin 2, neuronal |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| ARFGEF1 | ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) |
| ARIH2 | ariadne RBR E3 ubiquitin protein ligase 2 |
| ATG12 | autophagy related 12 |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| BCL9 | B-cell CLL/lymphoma 9 |
| BDH1 | 3-hydroxybutyrate dehydrogenase, type 1 |
| C17ORF62 | chromosome 17 open reading frame 62 |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CBX6 | chromobox homolog 6 |
| CCDC85C | coiled-coil domain containing 85C |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) |
| COPS7B | COP9 signalosome subunit 7B |
| CPT2 | carnitine palmitoyltransferase 2 |
| CYP2E1 | cytochrome P450, family 2, subfamily E, polypeptide 1 |
| DAXX | death-domain associated protein |
| DENND2A | DENN/MADD domain containing 2A |
| ENDOG | endonuclease G |
| ERCC2 | excision repair cross-complementation group 2 |
| ESRRA | estrogen-related receptor alpha |
| FADS2 | fatty acid desaturase 2 |
| FAF2 | Fas associated factor family member 2 |
| FARS2 | phenylalanyl-tRNA synthetase 2, mitochondrial |
| GAA | glucosidase, alpha; acid |
| GAS6 | growth arrest-specific 6 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 |
| HMHA1 | histocompatibility (minor) HA-1 |
| HOMER2 | homer scaffolding protein 2 |
| HOXB13 | homeobox B13 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| IGKV1D-13 | immunoglobulin kappa variable 1D-13 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
| IL13RA1 | interleukin 13 receptor, alpha 1 |
| KLHL24 | kelch-like family member 24 |
| KLHL3 | kelch-like family member 3 |
| KPNA6 | karyopherin alpha 6 (importin alpha 7) |
| KRT38 | keratin 38, type I |
| LITAF | lipopolysaccharide-induced TNF factor |
| LPP | LIM domain containing preferred translocation partner in lipoma |
| LPPR2 | lipid phosphate phosphatase-related protein type 2 |
| LRRC20 | leucine rich repeat containing 20 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) |
| MAST2 | microtubule associated serine/threonine kinase 2 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MICALL1 | MICAL-like 1 |
| MYO9B | myosin IXB |
| MZF1 | myeloid zinc finger 1 |
| NKX3-1 | NK3 homeobox 1 |
| NOTCH1 | notch 1 |
| NRP2 | neuropilin 2 |
| NUDT11 | nudix (nucleoside diphosphate linked moiety X)-type motif 11 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PDK2 | pyruvate dehydrogenase kinase, isozyme 2 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase |
| PHKG2 | phosphorylase kinase, gamma 2 (testis) |
| PLCD1 | phospholipase C, delta 1 |
| PLCE1 | phospholipase C, epsilon 1 |
| PODXL | podocalyxin-like |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PRKD2 | protein kinase D2 |
| RPL3 | ribosomal protein L3 |
| RPS21 | ribosomal protein S21 |
| SAMHD1 | SAM domain and HD domain 1 |
| SEC14L1 | SEC14-like 1 (S. cerevisiae) |
| SEC23A | Sec23 homolog A (S. cerevisiae) |
| SF3A2 | splicing factor 3a, subunit 2, 66kDa |
| SFTPB | surfactant protein B |
| SIRT6 | sirtuin 6 |
| SLC19A1 | solute carrier family 19 (folate transporter), member 1 |
| SLC31A1 | solute carrier family 31 (copper transporter), member 1 |
| SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| STK19 | serine/threonine kinase 19 |
| SUGP1 | SURP and G patch domain containing 1 |
| SURF1 | surfeit 1 |
| THBS3 | thrombospondin 3 |
| THG1L | tRNA-histidine guanylyltransferase 1-like (S. cerevisiae) |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TMCO6 | transmembrane and coiled-coil domains 6 |
| TMEM110 | transmembrane protein 110 |
| TMEM120B | transmembrane protein 120B |
| TMEM161A | transmembrane protein 161A |
| TOE1 | target of EGR1, member 1 (nuclear) |
| TRA2A | transformer 2 alpha homolog (Drosophila) |
| TRIM29 | tripartite motif containing 29 |
| TTLL4 | tubulin tyrosine ligase-like family member 4 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| WSCD1 | WSC domain containing 1 |
| ZBTB20 | zinc finger and BTB domain containing 20 |
| ZNF432 | zinc finger protein 432 |
| ZNF747 | zinc finger protein 747 |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 |
| Symbol | Name |
|---|---|
| ACAP2 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 |
| APPL1 | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 |
| ARHGAP5 | Rho GTPase activating protein 5 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| BAP1 | BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) |
| C1ORF109 | chromosome 1 open reading frame 109 |
| C1QTNF1 | C1q and tumor necrosis factor related protein 1 |
| C2CD5 | C2 calcium-dependent domain containing 5 |
| CCDC25 | coiled-coil domain containing 25 |
| CD53 | CD53 molecule |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) |
| CDC73 | cell division cycle 73 |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| CHUK | conserved helix-loop-helix ubiquitous kinase |
| CLDND1 | claudin domain containing 1 |
| CNTD2 | cyclin N-terminal domain containing 2 |
| COMMD10 | COMM domain containing 10 |
| CPOX | coproporphyrinogen oxidase |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DCK | deoxycytidine kinase |
| DEAF1 | DEAF1 transcription factor |
| DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal |
| DENND1B | DENN/MADD domain containing 1B |
| DPYD | dihydropyrimidine dehydrogenase |
| DSN1 | DSN1, MIS12 kinetochore complex component |
| ECT2 | epithelial cell transforming 2 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 |
| EIF1B | eukaryotic translation initiation factor 1B |
| EMC2 | ER membrane protein complex subunit 2 |
| ERBB2IP | erbb2 interacting protein |
| ERO1L | ERO1-like (S. cerevisiae) |
| EXOC5 | exocyst complex component 5 |
| FAM188A | family with sequence similarity 188, member A |
| FAM53B | family with sequence similarity 53, member B |
| FAR2 | fatty acyl CoA reductase 2 |
| FOXA1 | forkhead box A1 |
| FPGT | fucose-1-phosphate guanylyltransferase |
| FZD6 | frizzled class receptor 6 |
| GLB1L2 | galactosidase, beta 1-like 2 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 |
| IFNA17 | interferon, alpha 17 |
| KCTD3 | potassium channel tetramerization domain containing 3 |
| KIAA0894 | KIAA0894 protein |
| KIF20B | kinesin family member 20B |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 |
| LRIF1 | ligand dependent nuclear receptor interacting factor 1 |
| LYRM2 | LYR motif containing 2 |
| MAGT1 | magnesium transporter 1 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| MYNN | myoneurin |
| NIP7 | NIP7, nucleolar pre-rRNA processing protein |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NRSN2 | neurensin 2 |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| PAK1IP1 | PAK1 interacting protein 1 |
| PARP6 | poly (ADP-ribose) polymerase family, member 6 |
| PCNXL4 | pecanex-like 4 (Drosophila) |
| PIGA | phosphatidylinositol glycan anchor biosynthesis, class A |
| PLSCR1 | phospholipid scramblase 1 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A |
| RAD51AP1 | RAD51 associated protein 1 |
| RB1CC1 | RB1-inducible coiled-coil 1 |
| RNF144A | ring finger protein 144A |
| RNF38 | ring finger protein 38 |
| RPAP3 | RNA polymerase II associated protein 3 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RPRD1A | regulation of nuclear pre-mRNA domain containing 1A |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 |
| SAR1B | secretion associated, Ras related GTPase 1B |
| SCAMP5 | secretory carrier membrane protein 5 |
| SCMH1 | sex comb on midleg homolog 1 (Drosophila) |
| SDHAF3 | succinate dehydrogenase complex assembly factor 3 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 |
| SLC35A5 | solute carrier family 35, member A5 |
| SLC50A1 | solute carrier family 50 (sugar efflux transporter), member 1 |
| SLMO2 | slowmo homolog 2 (Drosophila) |
| SMAP1 | small ArfGAP 1 |
| SMS | spermine synthase |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
| STK39 | serine threonine kinase 39 |
| TOP2B | topoisomerase (DNA) II beta 180kDa |
| TRMT13 | tRNA methyltransferase 13 homolog (S. cerevisiae) |
| TRMT2B | tRNA methyltransferase 2 homolog B (S. cerevisiae) |
| TVP23B | trans-golgi network vesicle protein 23 homolog B (S. cerevisiae) |
| UBA2 | ubiquitin-like modifier activating enzyme 2 |
| UBA5 | ubiquitin-like modifier activating enzyme 5 |
| UFM1 | ubiquitin-fold modifier 1 |
| VWA9 | von Willebrand factor A domain containing 9 |
| WASF1 | WAS protein family, member 1 |
| WDR44 | WD repeat domain 44 |
| ZBTB11 | zinc finger and BTB domain containing 11 |
| ZNF195 | zinc finger protein 195 |
| ZNF217 | zinc finger protein 217 |
| ZNF354A | zinc finger protein 354A |
| ZNF580 | zinc finger protein 580 |
