| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the naloxone-4645 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| ADAMTS8 | ADAM metallopeptidase with thrombospondin type 1 motif, 8 |
| AGXT | alanine-glyoxylate aminotransferase |
| AKAP13 | A kinase (PRKA) anchor protein 13 |
| APOBEC3F | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 |
| ARTN | artemin |
| ASCL1 | achaete-scute family bHLH transcription factor 1 |
| CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit |
| CADM3 | cell adhesion molecule 3 |
| CCDC81 | coiled-coil domain containing 81 |
| CCL2 | chemokine (C-C motif) ligand 2 |
| CD163 | CD163 molecule |
| CD72 | CD72 molecule |
| CHRND | cholinergic receptor, nicotinic, delta (muscle) |
| CLEC11A | C-type lectin domain family 11, member A |
| COL19A1 | collagen, type XIX, alpha 1 |
| CPA2 | carboxypeptidase A2 (pancreatic) |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 |
| CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 |
| EGFL7 | EGF-like-domain, multiple 7 |
| EMX1 | empty spiracles homeobox 1 |
| ERCC4 | excision repair cross-complementation group 4 |
| FBRS | fibrosin |
| FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide |
| GLI2 | GLI family zinc finger 2 |
| GPR68 | G protein-coupled receptor 68 |
| GSTA1 | glutathione S-transferase alpha 1 |
| HIST1H1E | histone cluster 1, H1e |
| HPR | haptoglobin-related protein |
| IAPP | islet amyloid polypeptide |
| IFNA8 | interferon, alpha 8 |
| IGFBP7 | insulin-like growth factor binding protein 7 |
| IL36RN | interleukin 36 receptor antagonist |
| IRF5 | interferon regulatory factor 5 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 |
| KCNJ4 | potassium channel, inwardly rectifying subfamily J, member 4 |
| KCTD14 | potassium channel tetramerization domain containing 14 |
| KRT23 | keratin 23, type I |
| LATS1 | large tumor suppressor kinase 1 |
| LGALS8 | lectin, galactoside-binding, soluble, 8 |
| LILRA4 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LIPE | lipase, hormone-sensitive |
| LRRC37BP1 | leucine rich repeat containing 37B pseudogene 1 |
| MAGEB4 | melanoma antigen family B4 |
| MAPK11 | mitogen-activated protein kinase 11 |
| MCF2 | MCF.2 cell line derived transforming sequence |
| MCPH1 | microcephalin 1 |
| MGC2889 | uncharacterized protein MGC2889 |
| MRPS12 | mitochondrial ribosomal protein S12 |
| MRPS18C | mitochondrial ribosomal protein S18C |
| NEU3 | sialidase 3 (membrane sialidase) |
| NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 |
| NGF | nerve growth factor (beta polypeptide) |
| OLFM1 | olfactomedin 1 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 |
| PHF7 | PHD finger protein 7 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) |
| POLL | polymerase (DNA directed), lambda |
| POU1F1 | POU class 1 homeobox 1 |
| PPP1R1A | protein phosphatase 1, regulatory (inhibitor) subunit 1A |
| PRB4 | proline-rich protein BstNI subfamily 4 |
| PTBP3 | polypyrimidine tract binding protein 3 |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| PYY | peptide YY |
| RPL10L | ribosomal protein L10-like |
| SARM1 | sterile alpha and TIR motif containing 1 |
| SCNN1G | sodium channel, non voltage gated 1 gamma subunit |
| SFTPD | surfactant protein D |
| SGCA | sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein) |
| SLC16A4 | solute carrier family 16, member 4 |
| SLC17A2 | solute carrier family 17, member 2 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 |
| SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 |
| SNCG | synuclein, gamma (breast cancer-specific protein 1) |
| SOGA1 | suppressor of glucose, autophagy associated 1 |
| SPX | spexin hormone |
| STON1 | stonin 1 |
| STX7 | syntaxin 7 |
| SUGP1 | SURP and G patch domain containing 1 |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa |
| TAOK1 | TAO kinase 1 |
| TBC1D2 | TBC1 domain family, member 2 |
| TLR8 | toll-like receptor 8 |
| TMEM140 | transmembrane protein 140 |
| TOX3 | TOX high mobility group box family member 3 |
| TRIM10 | tripartite motif containing 10 |
| TRIM31 | tripartite motif containing 31 |
| TSPY1 | testis specific protein, Y-linked 1 |
| TSR3 | TSR3, 20S rRNA accumulation, homolog (S. cerevisiae) |
| TTC12 | tetratricopeptide repeat domain 12 |
| TTLL3 | tubulin tyrosine ligase-like family member 3 |
| TTLL5 | tubulin tyrosine ligase-like family member 5 |
| UGT2B15 | UDP glucuronosyltransferase 2 family, polypeptide B15 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNRF4 | zinc and ring finger 4 |
| Symbol | Name |
|---|---|
| ABCA11P | ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene |
| ACAD10 | acyl-CoA dehydrogenase family, member 10 |
| ADCY6 | adenylate cyclase 6 |
| ADGRG6 | adhesion G protein-coupled receptor G6 |
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| ANXA2P1 | annexin A2 pseudogene 1 |
| ARHGAP5 | Rho GTPase activating protein 5 |
| ARL14 | ADP-ribosylation factor-like 14 |
| ATP7B | ATPase, Cu++ transporting, beta polypeptide |
| AXIN1 | axin 1 |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 |
| BAK1 | BCL2-antagonist/killer 1 |
| C1RL | complement component 1, r subcomponent-like |
| C4ORF19 | chromosome 4 open reading frame 19 |
| CAPN15 | calpain 15 |
| CEP112 | centrosomal protein 112kDa |
| CHM | choroideremia (Rab escort protein 1) |
| CHMP6 | charged multivesicular body protein 6 |
| CLDND1 | claudin domain containing 1 |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CNP | 2',3'-cyclic nucleotide 3' phosphodiesterase |
| CRYL1 | crystallin, lambda 1 |
| CTNNBIP1 | catenin, beta interacting protein 1 |
| DBF4B | DBF4 zinc finger B |
| DHX35 | DEAH (Asp-Glu-Ala-His) box polypeptide 35 |
| DMTN | dematin actin binding protein |
| DNAL4 | dynein, axonemal, light chain 4 |
| EN1 | engrailed homeobox 1 |
| EN2 | engrailed homeobox 2 |
| ETNK2 | ethanolamine kinase 2 |
| ETV4 | ets variant 4 |
| EXOC5 | exocyst complex component 5 |
| FAM114A2 | family with sequence similarity 114, member A2 |
| FANCC | Fanconi anemia, complementation group C |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 |
| GID4 | GID complex subunit 4 |
| GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HIST1H1T | histone cluster 1, H1t |
| HMOX1 | heme oxygenase 1 |
| HYI | hydroxypyruvate isomerase (putative) |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| IPO8 | importin 8 |
| IQCG | IQ motif containing G |
| ITM2C | integral membrane protein 2C |
| KIAA0753 | KIAA0753 |
| KLC2 | kinesin light chain 2 |
| KRT34 | keratin 34, type I |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 |
| LOC100127972 | uncharacterized LOC100127972 |
| MANBA | mannosidase, beta A, lysosomal |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| NDP | Norrie disease (pseudoglioma) |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NID2 | nidogen 2 (osteonidogen) |
| NLK | nemo-like kinase |
| NUS1P3 | nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3 |
| NXPH4 | neurexophilin 4 |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
| PAK3 | p21 protein (Cdc42/Rac)-activated kinase 3 |
| PALMD | palmdelphin |
| PARD6A | par-6 family cell polarity regulator alpha |
| PARP3 | poly (ADP-ribose) polymerase family, member 3 |
| PLA2G15 | phospholipase A2, group XV |
| PLCD1 | phospholipase C, delta 1 |
| PLD3 | phospholipase D family, member 3 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| POLA2 | polymerase (DNA directed), alpha 2, accessory subunit |
| PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa |
| RAB33B | RAB33B, member RAS oncogene family |
| RBM38 | RNA binding motif protein 38 |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| ROM1 | retinal outer segment membrane protein 1 |
| RPP25 | ribonuclease P/MRP 25kDa subunit |
| RRAGB | Ras-related GTP binding B |
| SAMD9 | sterile alpha motif domain containing 9 |
| SARS2 | seryl-tRNA synthetase 2, mitochondrial |
| SDC3 | syndecan 3 |
| SLC35F6 | solute carrier family 35, member F6 |
| SLC4A1AP | solute carrier family 4 (anion exchanger), member 1, adaptor protein |
| SPIDR | scaffolding protein involved in DNA repair |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 |
| TGFBI | transforming growth factor, beta-induced, 68kDa |
| THOP1 | thimet oligopeptidase 1 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMEM132A | transmembrane protein 132A |
| TOR4A | torsin family 4, member A |
| URGCP | upregulator of cell proliferation |
| USP6NL | USP6 N-terminal like |
| WDR76 | WD repeat domain 76 |
| XAB2 | XPA binding protein 2 |
| ZBTB39 | zinc finger and BTB domain containing 39 |
| ZFHX3 | zinc finger homeobox 3 |
| ZNF276 | zinc finger protein 276 |
| ZNF76 | zinc finger protein 76 |
| ZNF813 | zinc finger protein 813 |
