| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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193 genes differentially expressed following the naloxone-5243 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCB8 | ATP-binding cassette, sub-family B (MDR/TAP), member 8 |
| ADAM19 | ADAM metallopeptidase domain 19 |
| AIM1L | absent in melanoma 1-like |
| AIM2 | absent in melanoma 2 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| APOBEC1 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 |
| AQP3 | aquaporin 3 (Gill blood group) |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| ATP6V0A2 | ATPase, H+ transporting, lysosomal V0 subunit a2 |
| ATPAF2 | ATP synthase mitochondrial F1 complex assembly factor 2 |
| C10ORF95 | chromosome 10 open reading frame 95 |
| C19ORF73 | chromosome 19 open reading frame 73 |
| C7ORF69 | chromosome 7 open reading frame 69 |
| CABP2 | calcium binding protein 2 |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CACNG1 | calcium channel, voltage-dependent, gamma subunit 1 |
| CALML5 | calmodulin-like 5 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CCDC40 | coiled-coil domain containing 40 |
| CD52 | CD52 molecule |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) |
| CDO1 | cysteine dioxygenase type 1 |
| CLTA | clathrin, light chain A |
| CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 |
| DEFA4 | defensin, alpha 4, corticostatin |
| DGKQ | diacylglycerol kinase, theta 110kDa |
| DICER1 | dicer 1, ribonuclease type III |
| DMPK | dystrophia myotonica-protein kinase |
| DPYS | dihydropyrimidinase |
| EGR1 | early growth response 1 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| FASLG | Fas ligand (TNF superfamily, member 6) |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa |
| FRMD4B | FERM domain containing 4B |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GM2A | GM2 ganglioside activator |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) |
| GP2 | glycoprotein 2 (zymogen granule membrane) |
| GPR39 | G protein-coupled receptor 39 |
| HIST1H2BN | histone cluster 1, H2bn |
| HIST1H3A | histone cluster 1, H3a |
| HLF | hepatic leukemia factor |
| IL2RB | interleukin 2 receptor, beta |
| INPP5J | inositol polyphosphate-5-phosphatase J |
| IRF8 | interferon regulatory factor 8 |
| IRS2 | insulin receptor substrate 2 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
| IZUMO4 | IZUMO family member 4 |
| KLHL22 | kelch-like family member 22 |
| KRT19P2 | keratin 19 pseudogene 2 |
| MAN1A2 | mannosidase, alpha, class 1A, member 2 |
| MAOA | monoamine oxidase A |
| MAP1A | microtubule-associated protein 1A |
| MAPRE3 | microtubule-associated protein, RP/EB family, member 3 |
| MARK2 | MAP/microtubule affinity-regulating kinase 2 |
| NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 |
| NLGN1 | neuroligin 1 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| OLFML2A | olfactomedin-like 2A |
| OR2H2 | olfactory receptor, family 2, subfamily H, member 2 |
| PARD6A | par-6 family cell polarity regulator alpha |
| PDE7B | phosphodiesterase 7B |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| PRPH2 | peripherin 2 (retinal degeneration, slow) |
| RARA | retinoic acid receptor, alpha |
| RGS10 | regulator of G-protein signaling 10 |
| RIMS3 | regulating synaptic membrane exocytosis 3 |
| RPL35A | ribosomal protein L35a |
| RUNDC3A | RUN domain containing 3A |
| RUNX1 | runt-related transcription factor 1 |
| RXRB | retinoid X receptor, beta |
| SBF1 | SET binding factor 1 |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SERHL2 | serine hydrolase-like 2 |
| SFRP4 | secreted frizzled-related protein 4 |
| SIM2 | single-minded family bHLH transcription factor 2 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 |
| SLC5A5 | solute carrier family 5 (sodium/iodide cotransporter), member 5 |
| SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| SYN2 | synapsin II |
| SYN3 | synapsin III |
| TBC1D8B | TBC1 domain family, member 8B (with GRAM domain) |
| TCHH | trichohyalin |
| TNC | tenascin C |
| TP63 | tumor protein p63 |
| TRAIP | TRAF interacting protein |
| TUBB2B | tubulin, beta 2B class IIb |
| UNC119 | unc-119 homolog (C. elegans) |
| VN1R1 | vomeronasal 1 receptor 1 |
| WNT2B | wingless-type MMTV integration site family, member 2B |
| XIAP | X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase |
| Symbol | Name |
|---|---|
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| ANXA2P3 | annexin A2 pseudogene 3 |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ATP6V1G2 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 |
| B9D2 | B9 protein domain 2 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| C1ORF35 | chromosome 1 open reading frame 35 |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CCDC9 | coiled-coil domain containing 9 |
| CDK20 | cyclin-dependent kinase 20 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| DOK1 | docking protein 1, 62kDa (downstream of tyrosine kinase 1) |
| DSCAM | Down syndrome cell adhesion molecule |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| ERCC6 | excision repair cross-complementation group 6 |
| ETV6 | ets variant 6 |
| FAM110B | family with sequence similarity 110, member B |
| FAN1 | FANCD2/FANCI-associated nuclease 1 |
| FBRS | fibrosin |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FLJ22184 | |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 |
| GK3P | glycerol kinase 3 pseudogene |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GPR27 | G protein-coupled receptor 27 |
| HLA-J | major histocompatibility complex, class I, J (pseudogene) |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| IGFBP6 | insulin-like growth factor binding protein 6 |
| IL17RA | interleukin 17 receptor A |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 |
| KLHL25 | kelch-like family member 25 |
| KLHL28 | kelch-like family member 28 |
| KRT13 | keratin 13, type I |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LOC390998 | ribosomal protein L10 pseudogene |
| MAP3K6 | mitogen-activated protein kinase kinase kinase 6 |
| MCOLN1 | mucolipin 1 |
| MINOS1P1 | mitochondrial inner membrane organizing system 1 pseudogene 1 |
| MMP2 | matrix metallopeptidase 2 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| NXPH4 | neurexophilin 4 |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| OR2B6 | olfactory receptor, family 2, subfamily B, member 6 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| PCDHA5 | protocadherin alpha 5 |
| PCDHA6 | protocadherin alpha 6 |
| PLA2G3 | phospholipase A2, group III |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PRODH | proline dehydrogenase (oxidase) 1 |
| RASAL1 | RAS protein activator like 1 (GAP1 like) |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| S100A7 | S100 calcium binding protein A7 |
| SAV1 | salvador family WW domain containing protein 1 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SENP7 | SUMO1/sentrin specific peptidase 7 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SETD1A | SET domain containing 1A |
| SLC12A6 | solute carrier family 12 (potassium/chloride transporter), member 6 |
| SLC9A5 | solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SOX12 | SRY (sex determining region Y)-box 12 |
| ST5 | suppression of tumorigenicity 5 |
| STRA6 | stimulated by retinoic acid 6 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TESK1 | testis-specific kinase 1 |
| THOP1 | thimet oligopeptidase 1 |
| TLE2 | transducin-like enhancer of split 2 |
| TMEM242 | transmembrane protein 242 |
| TNFSF18 | tumor necrosis factor (ligand) superfamily, member 18 |
| TRIM25 | tripartite motif containing 25 |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TUBA3D | tubulin, alpha 3d |
| UBOX5 | U-box domain containing 5 |
| USB1 | U6 snRNA biogenesis 1 |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| USP6NL | USP6 N-terminal like |
| VPS9D1 | VPS9 domain containing 1 |
| WDR25 | WD repeat domain 25 |
| WDR62 | WD repeat domain 62 |
| ZCCHC24 | zinc finger, CCHC domain containing 24 |
| ZNF16 | zinc finger protein 16 |
| ZNF492 | zinc finger protein 492 |
| ZNF506 | zinc finger protein 506 |
