| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the naloxone-5606 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM12 | ADAM metallopeptidase domain 12 |
| ADAM23 | ADAM metallopeptidase domain 23 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 |
| ADGRE1 | adhesion G protein-coupled receptor E1 |
| ALDOB | aldolase B, fructose-bisphosphate |
| ARHGAP6 | Rho GTPase activating protein 6 |
| ASAP3 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 |
| BAAT | bile acid CoA:amino acid N-acyltransferase |
| BFSP2 | beaded filament structural protein 2, phakinin |
| BUD31 | BUD31 homolog (S. cerevisiae) |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CAPN9 | calpain 9 |
| CARD10 | caspase recruitment domain family, member 10 |
| CASP4 | caspase 4, apoptosis-related cysteine peptidase |
| CCT8L2 | chaperonin containing TCP1, subunit 8 (theta)-like 2 |
| CD86 | CD86 molecule |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CDKN2A | cyclin-dependent kinase inhibitor 2A |
| CFAP69 | cilia and flagella associated protein 69 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| CIITA | class II, major histocompatibility complex, transactivator |
| CPM | carboxypeptidase M |
| CTSF | cathepsin F |
| CYTH4 | cytohesin 4 |
| EXOSC2 | exosome component 2 |
| FHL1 | four and a half LIM domains 1 |
| FOXP3 | forkhead box P3 |
| FRMD4B | FERM domain containing 4B |
| FXYD5 | FXYD domain containing ion transport regulator 5 |
| GAST | gastrin |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) |
| GJB3 | gap junction protein, beta 3, 31kDa |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O |
| GREB1L | growth regulation by estrogen in breast cancer-like |
| GRIP2 | glutamate receptor interacting protein 2 |
| GSTP1 | glutathione S-transferase pi 1 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 |
| HFE | hemochromatosis |
| HOXA10 | homeobox A10 |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IFT27 | intraflagellar transport 27 |
| INSR | insulin receptor |
| ITGA7 | integrin, alpha 7 |
| ITM2C | integral membrane protein 2C |
| KCNC1 | potassium channel, voltage gated Shaw related subfamily C, member 1 |
| KCNIP1 | Kv channel interacting protein 1 |
| KCNK2 | potassium channel, two pore domain subfamily K, member 2 |
| KIF13A | kinesin family member 13A |
| KSR1 | kinase suppressor of ras 1 |
| LAMA4 | laminin, alpha 4 |
| LDHB | lactate dehydrogenase B |
| LIN7A | lin-7 homolog A (C. elegans) |
| LRP4 | low density lipoprotein receptor-related protein 4 |
| LYVE1 | lymphatic vessel endothelial hyaluronan receptor 1 |
| MBD3 | methyl-CpG binding domain protein 3 |
| MEGF6 | multiple EGF-like-domains 6 |
| MEP1B | meprin A, beta |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming |
| NAG18 | NAG18 mRNA |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist |
| NEFL | neurofilament, light polypeptide |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NTRK3 | neurotrophic tyrosine kinase, receptor, type 3 |
| PAPPA2 | pappalysin 2 |
| PAX2 | paired box 2 |
| PFKFB2 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 |
| PHF7 | PHD finger protein 7 |
| PHLDB1 | pleckstrin homology-like domain, family B, member 1 |
| PIN1P1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1 |
| PKNOX1 | PBX/knotted 1 homeobox 1 |
| PLK3 | polo-like kinase 3 |
| POLL | polymerase (DNA directed), lambda |
| POM121L9P | POM121 transmembrane nucleoporin-like 9, pseudogene |
| POMT2 | protein-O-mannosyltransferase 2 |
| PPARD | peroxisome proliferator-activated receptor delta |
| PTAFR | platelet-activating factor receptor |
| RAC2 | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) |
| RNF208 | ring finger protein 208 |
| SAA3P | serum amyloid A3 pseudogene |
| SCLY | selenocysteine lyase |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SIX3 | SIX homeobox 3 |
| SLC30A3 | solute carrier family 30 (zinc transporter), member 3 |
| SPEG | SPEG complex locus |
| SPPL2B | signal peptide peptidase like 2B |
| SPRR2B | small proline-rich protein 2B |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 |
| SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 |
| TAPBP | TAP binding protein (tapasin) |
| TFCP2L1 | transcription factor CP2-like 1 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TOR4A | torsin family 4, member A |
| TRPM2 | transient receptor potential cation channel, subfamily M, member 2 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
| UPK3A | uroplakin 3A |
| VIM | vimentin |
| VPRBP | Vpr (HIV-1) binding protein |
| XIST | X inactive specific transcript (non-protein coding) |
| Symbol | Name |
|---|---|
| ABCA12 | ATP-binding cassette, sub-family A (ABC1), member 12 |
| ALOX15 | arachidonate 15-lipoxygenase |
| ALPK1 | alpha-kinase 1 |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C14ORF93 | chromosome 14 open reading frame 93 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| C2ORF54 | chromosome 2 open reading frame 54 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CAMKMT | calmodulin-lysine N-methyltransferase |
| CBX8 | chromobox homolog 8 |
| CFAP44 | cilia and flagella associated protein 44 |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CHST10 | carbohydrate sulfotransferase 10 |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CRY2 | cryptochrome circadian clock 2 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DUSP2 | dual specificity phosphatase 2 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| EFNA3 | ephrin-A3 |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| EPN1 | epsin 1 |
| FAM155A | family with sequence similarity 155, member A |
| FANCC | Fanconi anemia, complementation group C |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa |
| FOXN2 | forkhead box N2 |
| FRK | fyn-related Src family tyrosine kinase |
| FSD1 | fibronectin type III and SPRY domain containing 1 |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GFI1 | growth factor independent 1 transcription repressor |
| GPR3 | G protein-coupled receptor 3 |
| GRPR | gastrin-releasing peptide receptor |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HIST1H4E | histone cluster 1, H4e |
| HOXB2 | homeobox B2 |
| HS1BP3 | HCLS1 binding protein 3 |
| INO80D | INO80 complex subunit D |
| IREB2 | iron-responsive element binding protein 2 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| KIAA0894 | KIAA0894 protein |
| KLF2 | Kruppel-like factor 2 |
| LAMP3 | lysosomal-associated membrane protein 3 |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| LOXL3 | lysyl oxidase-like 3 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| LRP5L | low density lipoprotein receptor-related protein 5-like |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| PRSS22 | protease, serine, 22 |
| QPCTL | glutaminyl-peptide cyclotransferase-like |
| RAB3D | RAB3D, member RAS oncogene family |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RFXAP | regulatory factor X-associated protein |
| RNF39 | ring finger protein 39 |
| RPGR | retinitis pigmentosa GTPase regulator |
| RPL10L | ribosomal protein L10-like |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| S100A2 | S100 calcium binding protein A2 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SENP7 | SUMO1/sentrin specific peptidase 7 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 |
| STIM1 | stromal interaction molecule 1 |
| STRA6 | stimulated by retinoic acid 6 |
| STX1A | syntaxin 1A (brain) |
| SYNC | syncoilin, intermediate filament protein |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| THBS3 | thrombospondin 3 |
| THNSL2 | threonine synthase-like 2 (S. cerevisiae) |
| TM6SF1 | transmembrane 6 superfamily member 1 |
| TPCN1 | two pore segment channel 1 |
| TRIM36 | tripartite motif containing 36 |
| TRPC5 | transient receptor potential cation channel, subfamily C, member 5 |
| TSGA10 | testis specific, 10 |
| UBXN6 | UBX domain protein 6 |
| VEZT | vezatin, adherens junctions transmembrane protein |
| XDH | xanthine dehydrogenase |
| ZBTB44 | zinc finger and BTB domain containing 44 |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZNF141 | zinc finger protein 141 |
| ZNF750 | zinc finger protein 750 |
| ZNF862 | zinc finger protein 862 |
