| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the naltrexone-1363 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ANKRA2 | ankyrin repeat, family A (RFXANK-like), 2 |
| ANKRD12 | ankyrin repeat domain 12 |
| AP5Z1 | adaptor-related protein complex 5, zeta 1 subunit |
| ASMTL | acetylserotonin O-methyltransferase-like |
| ATM | ATM serine/threonine kinase |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D |
| AZI2 | 5-azacytidine induced 2 |
| BMPR1A | bone morphogenetic protein receptor, type IA |
| BRAP | BRCA1 associated protein |
| C12ORF29 | chromosome 12 open reading frame 29 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 |
| CCPG1 | cell cycle progression 1 |
| CD101 | CD101 molecule |
| CD8B | CD8b molecule |
| CDC73 | cell division cycle 73 |
| CDHR2 | cadherin-related family member 2 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CLN8 | ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) |
| CTNNBIP1 | catenin, beta interacting protein 1 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 |
| DAZAP2 | DAZ associated protein 2 |
| DERL2 | derlin 2 |
| DSCR3 | Down syndrome critical region 3 |
| DYRK2 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 |
| ENG | endoglin |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| FAM134B | family with sequence similarity 134, member B |
| FAM57A | family with sequence similarity 57, member A |
| FAM64A | family with sequence similarity 64, member A |
| FASTK | Fas-activated serine/threonine kinase |
| FBXO21 | F-box protein 21 |
| FER1L4 | fer-1-like family member 4, pseudogene (functional) |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) |
| FPR2 | formyl peptide receptor 2 |
| FTH1P5 | ferritin, heavy polypeptide 1 pseudogene 5 |
| GIMAP5 | GTPase, IMAP family member 5 |
| GIT2 | G protein-coupled receptor kinase interacting ArfGAP 2 |
| GLTSCR1L | GLTSCR1-like |
| GRK6 | G protein-coupled receptor kinase 6 |
| HIPK2 | homeodomain interacting protein kinase 2 |
| HIST1H1D | histone cluster 1, H1d |
| IER3 | immediate early response 3 |
| IL13RA1 | interleukin 13 receptor, alpha 1 |
| IL1R2 | interleukin 1 receptor, type II |
| INPP5K | inositol polyphosphate-5-phosphatase K |
| JMJD1C | jumonji domain containing 1C |
| KIR2DS1 | killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 |
| KRIT1 | KRIT1, ankyrin repeat containing |
| LAMP1 | lysosomal-associated membrane protein 1 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) |
| LGALS8 | lectin, galactoside-binding, soluble, 8 |
| LIN7C | lin-7 homolog C (C. elegans) |
| LMNA | lamin A/C |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| MED13L | mediator complex subunit 13-like |
| MPP6 | membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) |
| MPPED1 | metallophosphoesterase domain containing 1 |
| MSH3 | mutS homolog 3 |
| NDE1 | nudE neurodevelopment protein 1 |
| PARG | poly (ADP-ribose) glycohydrolase |
| PDCD11 | programmed cell death 11 |
| PHF7 | PHD finger protein 7 |
| PIGK | phosphatidylinositol glycan anchor biosynthesis, class K |
| PIGZ | phosphatidylinositol glycan anchor biosynthesis, class Z |
| PLSCR1 | phospholipid scramblase 1 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| PPCS | phosphopantothenoylcysteine synthetase |
| PPM1B | protein phosphatase, Mg2+/Mn2+ dependent, 1B |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme |
| PPP1R16B | protein phosphatase 1, regulatory subunit 16B |
| PRRC2C | proline-rich coiled-coil 2C |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
| RAB5C | RAB5C, member RAS oncogene family |
| RANBP9 | RAN binding protein 9 |
| RDH11 | retinol dehydrogenase 11 (all-trans/9-cis/11-cis) |
| RGS1 | regulator of G-protein signaling 1 |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 |
| SLC33A1 | solute carrier family 33 (acetyl-CoA transporter), member 1 |
| SMG5 | SMG5 nonsense mediated mRNA decay factor |
| SOCS5 | suppressor of cytokine signaling 5 |
| SP3 | Sp3 transcription factor |
| SRSF11 | serine/arginine-rich splicing factor 11 |
| ST8SIA5 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 |
| SUMO1 | small ubiquitin-like modifier 1 |
| TCF4 | transcription factor 4 |
| TIA1 | TIA1 cytotoxic granule-associated RNA binding protein |
| TMED7 | transmembrane emp24 protein transport domain containing 7 |
| TNPO3 | transportin 3 |
| TRA | T cell receptor alpha locus |
| TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase |
| TSPYL2 | TSPY-like 2 |
| TXNRD2 | thioredoxin reductase 2 |
| UBXN2B | UBX domain protein 2B |
| ZC3H7A | zinc finger CCCH-type containing 7A |
| ZNF268 | zinc finger protein 268 |
| ZNF747 | zinc finger protein 747 |
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| ADAM15 | ADAM metallopeptidase domain 15 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 |
| ALPK1 | alpha-kinase 1 |
| ANXA6 | annexin A6 |
| APH1A | APH1A gamma secretase subunit |
| ARHGAP4 | Rho GTPase activating protein 4 |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| BCL7B | B-cell CLL/lymphoma 7B |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CAMTA2 | calmodulin binding transcription activator 2 |
| CAPN15 | calpain 15 |
| CDK2AP2 | cyclin-dependent kinase 2 associated protein 2 |
| CEP170B | centrosomal protein 170B |
| CEP72 | centrosomal protein 72kDa |
| CHRNA2 | cholinergic receptor, nicotinic, alpha 2 (neuronal) |
| CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 |
| CIC | capicua transcriptional repressor |
| CNTD2 | cyclin N-terminal domain containing 2 |
| CPA2 | carboxypeptidase A2 (pancreatic) |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) |
| DPH2 | DPH2 homolog (S. cerevisiae) |
| DSN1 | DSN1, MIS12 kinetochore complex component |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 |
| FAM114A1 | family with sequence similarity 114, member A1 |
| FANCC | Fanconi anemia, complementation group C |
| FGF4 | fibroblast growth factor 4 |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| GATAD2A | GATA zinc finger domain containing 2A |
| GIN1 | gypsy retrotransposon integrase 1 |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GRM6 | glutamate receptor, metabotropic 6 |
| GTF2IRD1 | GTF2I repeat domain containing 1 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HIST1H1C | histone cluster 1, H1c |
| IDO1 | indoleamine 2,3-dioxygenase 1 |
| IFI30 | interferon, gamma-inducible protein 30 |
| IFITM3 | interferon induced transmembrane protein 3 |
| IL2RB | interleukin 2 receptor, beta |
| IP6K1 | inositol hexakisphosphate kinase 1 |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| KCTD3 | potassium channel tetramerization domain containing 3 |
| KIAA0894 | KIAA0894 protein |
| KIF3B | kinesin family member 3B |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 |
| LMBR1L | limb development membrane protein 1-like |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| MAPK10 | mitogen-activated protein kinase 10 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 |
| MDN1 | MDN1, midasin homolog (yeast) |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MGAM | maltase-glucoamylase |
| MMS19 | MMS19 nucleotide excision repair homolog (S. cerevisiae) |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MTERF4 | mitochondrial transcription termination factor 4 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| NFE2 | nuclear factor, erythroid 2 |
| ORC2 | origin recognition complex, subunit 2 |
| ORC3 | origin recognition complex, subunit 3 |
| PARM1 | prostate androgen-regulated mucin-like protein 1 |
| PDIA3 | protein disulfide isomerase family A, member 3 |
| PDLIM2 | PDZ and LIM domain 2 (mystique) |
| PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
| PHACTR4 | phosphatase and actin regulator 4 |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| RBBP5 | retinoblastoma binding protein 5 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RUFY2 | RUN and FYVE domain containing 2 |
| SELP | selectin P (granule membrane protein 140kDa, antigen CD62) |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 |
| SLC25A22 | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 |
| SLC50A1 | solute carrier family 50 (sugar efflux transporter), member 1 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SNTA1 | syntrophin, alpha 1 |
| SPI1 | Spi-1 proto-oncogene |
| STAU2 | staufen double-stranded RNA binding protein 2 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TAF6 | TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa |
| TESK2 | testis-specific kinase 2 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 |
| TMEM53 | transmembrane protein 53 |
| TMPRSS6 | transmembrane protease, serine 6 |
| TRMT2B | tRNA methyltransferase 2 homolog B (S. cerevisiae) |
| TUBA3C | tubulin, alpha 3c |
| TXLNA | taxilin alpha |
| UBE2NL | ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) |
| USB1 | U6 snRNA biogenesis 1 |
| WBP2 | WW domain binding protein 2 |
| WDR19 | WD repeat domain 19 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZNF408 | zinc finger protein 408 |
| ZNF652 | zinc finger protein 652 |
