| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the naltrexone-2047 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABR | active BCR-related |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 |
| ANXA10 | annexin A10 |
| APOL2 | apolipoprotein L, 2 |
| ARAP1 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 |
| ATP10A | ATPase, class V, type 10A |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide |
| BCORL1 | BCL6 corepressor-like 1 |
| BIN1 | bridging integrator 1 |
| C9ORF156 | chromosome 9 open reading frame 156 |
| CACNA1I | calcium channel, voltage-dependent, T type, alpha 1I subunit |
| CARD8 | caspase recruitment domain family, member 8 |
| CORO1A | coronin, actin binding protein, 1A |
| CORO2A | coronin, actin binding protein, 2A |
| DHODH | dihydroorotate dehydrogenase (quinone) |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| DTX2P1-UPK3BP1-PMS2P11 | DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene |
| DXO | decapping exoribonuclease |
| EGR2 | early growth response 2 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa |
| EMC3 | ER membrane protein complex subunit 3 |
| ESRRG | estrogen-related receptor gamma |
| FAM184A | family with sequence similarity 184, member A |
| FER | fer (fps/fes related) tyrosine kinase |
| FOXA2 | forkhead box A2 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GLP1R | glucagon-like peptide 1 receptor |
| GLYR1 | glyoxylate reductase 1 homolog (Arabidopsis) |
| GM2A | GM2 ganglioside activator |
| GRAMD4 | GRAM domain containing 4 |
| HEG1 | heart development protein with EGF-like domains 1 |
| HIST1H4D | histone cluster 1, H4d |
| HIST1H4E | histone cluster 1, H4e |
| HLA-DOA | major histocompatibility complex, class II, DO alpha |
| HMGN5 | high mobility group nucleosome binding domain 5 |
| HOMER3 | homer scaffolding protein 3 |
| HOXB5 | homeobox B5 |
| ICK | intestinal cell (MAK-like) kinase |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| ITGA2B | integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) |
| IVD | isovaleryl-CoA dehydrogenase |
| KDM4C | lysine (K)-specific demethylase 4C |
| KDM5A | lysine (K)-specific demethylase 5A |
| KIFC3 | kinesin family member C3 |
| LAMP1 | lysosomal-associated membrane protein 1 |
| LIN7B | lin-7 homolog B (C. elegans) |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MCTP1 | multiple C2 domains, transmembrane 1 |
| MED28 | mediator complex subunit 28 |
| MTAP | methylthioadenosine phosphorylase |
| MXD4 | MAX dimerization protein 4 |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NAA38 | N(alpha)-acetyltransferase 38, NatC auxiliary subunit |
| NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2) |
| NCKIPSD | NCK interacting protein with SH3 domain |
| NEK1 | NIMA-related kinase 1 |
| NPFFR1 | neuropeptide FF receptor 1 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) |
| PHF20L1 | PHD finger protein 20-like 1 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) |
| PRKAR2A | protein kinase, cAMP-dependent, regulatory, type II, alpha |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
| RABGAP1 | RAB GTPase activating protein 1 |
| RALB | v-ral simian leukemia viral oncogene homolog B |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 |
| RBM19 | RNA binding motif protein 19 |
| RHOBTB3 | Rho-related BTB domain containing 3 |
| RHOT2 | ras homolog family member T2 |
| S1PR1 | sphingosine-1-phosphate receptor 1 |
| SCAPER | S-phase cyclin A-associated protein in the ER |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SH3BP2 | SH3-domain binding protein 2 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SMAD5 | SMAD family member 5 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SPATA5L1 | spermatogenesis associated 5-like 1 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like |
| ST6GALNAC4 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 |
| TBC1D22A | TBC1 domain family, member 22A |
| TEX261 | testis expressed 261 |
| TGFA | transforming growth factor, alpha |
| TGFB3 | transforming growth factor, beta 3 |
| THEMIS2 | thymocyte selection associated family member 2 |
| TLK1 | tousled-like kinase 1 |
| TLN2 | talin 2 |
| TMEM159 | transmembrane protein 159 |
| TRIM23 | tripartite motif containing 23 |
| TXLNG | taxilin gamma |
| ULK2 | unc-51 like autophagy activating kinase 2 |
| UPF1 | UPF1 regulator of nonsense transcripts homolog (yeast) |
| ZFP30 | ZFP30 zinc finger protein |
| ZNF286A | zinc finger protein 286A |
| ZNF444 | zinc finger protein 444 |
| Symbol | Name |
|---|---|
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| ARRB2 | arrestin, beta 2 |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| BMP15 | bone morphogenetic protein 15 |
| C19ORF54 | chromosome 19 open reading frame 54 |
| C1QTNF1 | C1q and tumor necrosis factor related protein 1 |
| CCDC85C | coiled-coil domain containing 85C |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| CLDN1 | claudin 1 |
| CLIP2 | CAP-GLY domain containing linker protein 2 |
| CLK3 | CDC-like kinase 3 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| COMMD10 | COMM domain containing 10 |
| CST4 | cystatin S |
| CWC25 | CWC25 spliceosome-associated protein homolog (S. cerevisiae) |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DNAL4 | dynein, axonemal, light chain 4 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| EMP3 | epithelial membrane protein 3 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| EVPL | envoplakin |
| EXO1 | exonuclease 1 |
| FBXW12 | F-box and WD repeat domain containing 12 |
| FPGS | folylpolyglutamate synthase |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| GBX2 | gastrulation brain homeobox 2 |
| GLDC | glycine dehydrogenase (decarboxylating) |
| GNA12 | guanine nucleotide binding protein (G protein) alpha 12 |
| GPATCH2L | G patch domain containing 2-like |
| H2AFY2 | H2A histone family, member Y2 |
| HOXC13 | homeobox C13 |
| INPPL1 | inositol polyphosphate phosphatase-like 1 |
| IPPK | inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
| ISYNA1 | inositol-3-phosphate synthase 1 |
| KIF13B | kinesin family member 13B |
| KRT86 | keratin 86, type II |
| LOC730101 | uncharacterized LOC730101 |
| LYPLA2P1 | lysophospholipase II pseudogene 1 |
| MAP4K2 | mitogen-activated protein kinase kinase kinase kinase 2 |
| MATN3 | matrilin 3 |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MITF | microphthalmia-associated transcription factor |
| MON1B | MON1 secretory trafficking family member B |
| MOSPD3 | motile sperm domain containing 3 |
| MPC1 | mitochondrial pyruvate carrier 1 |
| MUM1 | melanoma associated antigen (mutated) 1 |
| NAGPA | N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase |
| NCS1 | neuronal calcium sensor 1 |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| NUBP2 | nucleotide binding protein 2 |
| OGFRL1 | opioid growth factor receptor-like 1 |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) |
| PDZK1 | PDZ domain containing 1 |
| PEX26 | peroxisomal biogenesis factor 26 |
| PGS1 | phosphatidylglycerophosphate synthase 1 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PLCD1 | phospholipase C, delta 1 |
| POLR1B | polymerase (RNA) I polypeptide B, 128kDa |
| POLR3D | polymerase (RNA) III (DNA directed) polypeptide D, 44kDa |
| POMT1 | protein-O-mannosyltransferase 1 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PRR15L | proline rich 15-like |
| RAB8B | RAB8B, member RAS oncogene family |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RFWD3 | ring finger and WD repeat domain 3 |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| SEC61A2 | Sec61 alpha 2 subunit (S. cerevisiae) |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC37A1 | solute carrier family 37 (glucose-6-phosphate transporter), member 1 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SPEG | SPEG complex locus |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 |
| STK16 | serine/threonine kinase 16 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TBC1D12 | TBC1 domain family, member 12 |
| TEAD3 | TEA domain family member 3 |
| TESK1 | testis-specific kinase 1 |
| TM7SF2 | transmembrane 7 superfamily member 2 |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TMCC2 | transmembrane and coiled-coil domain family 2 |
| TNRC6B | trinucleotide repeat containing 6B |
| TPMT | thiopurine S-methyltransferase |
| TPRA1 | transmembrane protein, adipocyte asscociated 1 |
| TRAPPC6A | trafficking protein particle complex 6A |
| TRIM45 | tripartite motif containing 45 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein |
| TSKU | tsukushi, small leucine rich proteoglycan |
| TTBK2 | tau tubulin kinase 2 |
| TUBA3C | tubulin, alpha 3c |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 |
| WDR76 | WD repeat domain 76 |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZNF211 | zinc finger protein 211 |
| ZNF580 | zinc finger protein 580 |
| ZNF8 | zinc finger protein 8 |
