| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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194 genes differentially expressed following the naltrexone-2209 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTL8 | actin-like 8 |
| ADGRL3 | adhesion G protein-coupled receptor L3 |
| AGAP2 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 |
| AKAP11 | A kinase (PRKA) anchor protein 11 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein |
| APBA1 | amyloid beta (A4) precursor protein-binding, family A, member 1 |
| APC | adenomatous polyposis coli |
| ASAP3 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 |
| BRD7P3 | bromodomain containing 7 pseudogene 3 |
| BTN2A1 | butyrophilin, subfamily 2, member A1 |
| CALCR | calcitonin receptor |
| CAMK2B | calcium/calmodulin-dependent protein kinase II beta |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CCNK | cyclin K |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CFAP45 | cilia and flagella associated protein 45 |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| COL1A1 | collagen, type I, alpha 1 |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| DDR1-AS1 | DDR1 antisense RNA 1 (head to head) |
| DDX28 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 |
| DGCR8 | DGCR8 microprocessor complex subunit |
| DNAH17 | dynein, axonemal, heavy chain 17 |
| DOCK6 | dedicator of cytokinesis 6 |
| DPY19L1 | dpy-19-like 1 (C. elegans) |
| EPB41L4A | erythrocyte membrane protein band 4.1 like 4A |
| ERCC4 | excision repair cross-complementation group 4 |
| F13A1 | coagulation factor XIII, A1 polypeptide |
| FBLN1 | fibulin 1 |
| FOXG1 | forkhead box G1 |
| FXYD5 | FXYD domain containing ion transport regulator 5 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) |
| GCNT4 | glucosaminyl (N-acetyl) transferase 4, core 2 |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HBEGF | heparin-binding EGF-like growth factor |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) |
| HOXA10 | homeobox A10 |
| JAM3 | junctional adhesion molecule 3 |
| KIAA0125 | KIAA0125 |
| KRT83 | keratin 83, type II |
| LAMP1 | lysosomal-associated membrane protein 1 |
| LARP7 | La ribonucleoprotein domain family, member 7 |
| MED18 | mediator complex subunit 18 |
| MGEA5 | meningioma expressed antigen 5 (hyaluronidase) |
| MKL1 | megakaryoblastic leukemia (translocation) 1 |
| NF2 | neurofibromin 2 (merlin) |
| NNMT | nicotinamide N-methyltransferase |
| NOX5 | NADPH oxidase, EF-hand calcium binding domain 5 |
| NPC1 | Niemann-Pick disease, type C1 |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| NUDT7 | nudix (nucleoside diphosphate linked moiety X)-type motif 7 |
| OGDHL | oxoglutarate dehydrogenase-like |
| ONECUT2 | one cut homeobox 2 |
| OR10J1 | olfactory receptor, family 10, subfamily J, member 1 |
| PCNX | pecanex homolog (Drosophila) |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) |
| PKD2L2 | polycystic kidney disease 2-like 2 |
| PLCD1 | phospholipase C, delta 1 |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| PSG6 | pregnancy specific beta-1-glycoprotein 6 |
| RABGAP1L | RAB GTPase activating protein 1-like |
| RB1 | retinoblastoma 1 |
| RBM48 | RNA binding motif protein 48 |
| RCHY1 | ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| SERHL2 | serine hydrolase-like 2 |
| SKIL | SKI-like proto-oncogene |
| SLC10A1 | solute carrier family 10 (sodium/bile acid cotransporter), member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 |
| SORT1 | sortilin 1 |
| SPIB | Spi-B transcription factor (Spi-1/PU.1 related) |
| SPN | sialophorin |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) |
| ST20 | suppressor of tumorigenicity 20 |
| STK24 | serine/threonine kinase 24 |
| SUGP1 | SURP and G patch domain containing 1 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TAPBP | TAP binding protein (tapasin) |
| TRANK1 | tetratricopeptide repeat and ankyrin repeat containing 1 |
| TRMT2B | tRNA methyltransferase 2 homolog B (S. cerevisiae) |
| USP12 | ubiquitin specific peptidase 12 |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) |
| WAPAL | wings apart-like homolog (Drosophila) |
| WDR55 | WD repeat domain 55 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZCCHC14 | zinc finger, CCHC domain containing 14 |
| ZMYND8 | zinc finger, MYND-type containing 8 |
| ZNF652 | zinc finger protein 652 |
| Symbol | Name |
|---|---|
| ADGRE5 | adhesion G protein-coupled receptor E5 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| APOD | apolipoprotein D |
| ARC | activity-regulated cytoskeleton-associated protein |
| ARRB1 | arrestin, beta 1 |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| BGLAP | bone gamma-carboxyglutamate (gla) protein |
| C17ORF70 | chromosome 17 open reading frame 70 |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| C2ORF54 | chromosome 2 open reading frame 54 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CASZ1 | castor zinc finger 1 |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CDK3 | cyclin-dependent kinase 3 |
| CIC | capicua transcriptional repressor |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CORO7 | coronin 7 |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DHX8 | DEAH (Asp-Glu-Ala-His) box polypeptide 8 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DOK5 | docking protein 5 |
| DSPP | dentin sialophosphoprotein |
| DVL1 | dishevelled segment polarity protein 1 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| EMID1 | EMI domain containing 1 |
| ETNK2 | ethanolamine kinase 2 |
| FAM46C | family with sequence similarity 46, member C |
| FFAR2 | free fatty acid receptor 2 |
| FUT4 | fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GPX2 | glutathione peroxidase 2 |
| GRPR | gastrin-releasing peptide receptor |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HDAC5 | histone deacetylase 5 |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H3B | histone cluster 1, H3b |
| HIST1H4A | histone cluster 1, H4a |
| HOXA4 | homeobox A4 |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| KCNN2 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LYRM9 | LYR motif containing 9 |
| MED9 | mediator complex subunit 9 |
| MGAT1 | mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase |
| NDE1 | nudE neurodevelopment protein 1 |
| NEUROD4 | neuronal differentiation 4 |
| NOL10 | nucleolar protein 10 |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PIGZ | phosphatidylinositol glycan anchor biosynthesis, class Z |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PLA2G3 | phospholipase A2, group III |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) |
| PRSS16 | protease, serine, 16 (thymus) |
| PTK6 | protein tyrosine kinase 6 |
| RAB3D | RAB3D, member RAS oncogene family |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RGS19 | regulator of G-protein signaling 19 |
| RNF2 | ring finger protein 2 |
| S100A4 | S100 calcium binding protein A4 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SECTM1 | secreted and transmembrane 1 |
| SETD1A | SET domain containing 1A |
| SF3A2 | splicing factor 3a, subunit 2, 66kDa |
| SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) |
| SIPA1 | signal-induced proliferation-associated 1 |
| SIX1 | SIX homeobox 1 |
| SKI | SKI proto-oncogene |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SPATA2L | spermatogenesis associated 2-like |
| STAG3 | stromal antigen 3 |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 |
| SYNC | syncoilin, intermediate filament protein |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TEX40 | testis expressed 40 |
| TH | tyrosine hydroxylase |
| TLN1 | talin 1 |
| TLR2 | toll-like receptor 2 |
| TMLHE | trimethyllysine hydroxylase, epsilon |
| TMPRSS4 | transmembrane protease, serine 4 |
| TMUB2 | transmembrane and ubiquitin-like domain containing 2 |
| TTBK2 | tau tubulin kinase 2 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| TUBA3C | tubulin, alpha 3c |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| VAX2 | ventral anterior homeobox 2 |
| WDR76 | WD repeat domain 76 |
| WLS | wntless Wnt ligand secretion mediator |
| XDH | xanthine dehydrogenase |
| XYLT2 | xylosyltransferase II |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZNF506 | zinc finger protein 506 |
| ZNF574 | zinc finger protein 574 |