| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the naltrexone-6241 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCD1 | ATP-binding cassette, sub-family D (ALD), member 1 |
| ACOX1 | acyl-CoA oxidase 1, palmitoyl |
| AMT | aminomethyltransferase |
| AP4E1 | adaptor-related protein complex 4, epsilon 1 subunit |
| APOL2 | apolipoprotein L, 2 |
| AQP9 | aquaporin 9 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ATN1 | atrophin 1 |
| ATP9A | ATPase, class II, type 9A |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| BAIAP2 | BAI1-associated protein 2 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B |
| BMP4 | bone morphogenetic protein 4 |
| BRF1 | BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit |
| C14ORF1 | chromosome 14 open reading frame 1 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 |
| CEP135 | centrosomal protein 135kDa |
| CEP162 | centrosomal protein 162kDa |
| CNN1 | calponin 1, basic, smooth muscle |
| COL4A1 | collagen, type IV, alpha 1 |
| CRYGC | crystallin, gamma C |
| CTSF | cathepsin F |
| CUL4B | cullin 4B |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| DOK4 | docking protein 4 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| FLJ22184 | |
| FST | follistatin |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) |
| GRM1 | glutamate receptor, metabotropic 1 |
| HBS1L | HBS1-like translational GTPase |
| HIGD2A | HIG1 hypoxia inducible domain family, member 2A |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like |
| HOXC8 | homeobox C8 |
| HPSE2 | heparanase 2 (inactive) |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase |
| ICK | intestinal cell (MAK-like) kinase |
| IDUA | iduronidase, alpha-L- |
| IL5RA | interleukin 5 receptor, alpha |
| INPP5J | inositol polyphosphate-5-phosphatase J |
| IQCA1 | IQ motif containing with AAA domain 1 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| ITGA8 | integrin, alpha 8 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KANSL3 | KAT8 regulatory NSL complex subunit 3 |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KLK12 | kallikrein-related peptidase 12 |
| LUZP1 | leucine zipper protein 1 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MEF2D | myocyte enhancer factor 2D |
| MYBPC3 | myosin binding protein C, cardiac |
| NGLY1 | N-glycanase 1 |
| NIPAL2 | NIPA-like domain containing 2 |
| NR2C1 | nuclear receptor subfamily 2, group C, member 1 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| PAQR6 | progestin and adipoQ receptor family member VI |
| PART1 | prostate androgen-regulated transcript 1 (non-protein coding) |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PLSCR3 | phospholipid scramblase 3 |
| POLL | polymerase (DNA directed), lambda |
| PPM1F | protein phosphatase, Mg2+/Mn2+ dependent, 1F |
| PPP1R14D | protein phosphatase 1, regulatory (inhibitor) subunit 14D |
| PTPN22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) |
| QKI | QKI, KH domain containing, RNA binding |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RASAL2 | RAS protein activator like 2 |
| RPLP2 | ribosomal protein, large, P2 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
| SHARPIN | SHANK-associated RH domain interactor |
| SLC35F5 | solute carrier family 35, member F5 |
| SLC5A5 | solute carrier family 5 (sodium/iodide cotransporter), member 5 |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SPPL2B | signal peptide peptidase like 2B |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 |
| SYMPK | symplekin |
| SYNC | syncoilin, intermediate filament protein |
| TCF3 | transcription factor 3 |
| THRA | thyroid hormone receptor, alpha |
| TIMM8A | translocase of inner mitochondrial membrane 8 homolog A (yeast) |
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 |
| TPD52 | tumor protein D52 |
| TRAK1 | trafficking protein, kinesin binding 1 |
| TRIB2 | tribbles pseudokinase 2 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TSNAXIP1 | translin-associated factor X interacting protein 1 |
| TSSK2 | testis-specific serine kinase 2 |
| TTC28 | tetratricopeptide repeat domain 28 |
| TXNL4A | thioredoxin-like 4A |
| UBOX5 | U-box domain containing 5 |
| UBTD1 | ubiquitin domain containing 1 |
| VASH2 | vasohibin 2 |
| VPS13D | vacuolar protein sorting 13 homolog D (S. cerevisiae) |
| WDR25 | WD repeat domain 25 |
| WSCD1 | WSC domain containing 1 |
| YY1 | YY1 transcription factor |
| Symbol | Name |
|---|---|
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| AKAP12 | A kinase (PRKA) anchor protein 12 |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| ARL15 | ADP-ribosylation factor-like 15 |
| ARMC6 | armadillo repeat containing 6 |
| ASB7 | ankyrin repeat and SOCS box containing 7 |
| AXIN1 | axin 1 |
| BAHD1 | bromo adjacent homology domain containing 1 |
| BAK1 | BCL2-antagonist/killer 1 |
| BCOR | BCL6 corepressor |
| C16ORF45 | chromosome 16 open reading frame 45 |
| C17ORF80 | chromosome 17 open reading frame 80 |
| C1ORF35 | chromosome 1 open reading frame 35 |
| C5 | complement component 5 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CBR4 | carbonyl reductase 4 |
| CFD | complement factor D (adipsin) |
| CIDEC | cell death-inducing DFFA-like effector c |
| DCTN4 | dynactin 4 (p62) |
| DNMBP | dynamin binding protein |
| EDC3 | enhancer of mRNA decapping 3 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| EXOC5 | exocyst complex component 5 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FADS3 | fatty acid desaturase 3 |
| FAM114A2 | family with sequence similarity 114, member A2 |
| FAM160B2 | family with sequence similarity 160, member B2 |
| FBRS | fibrosin |
| FNTB | farnesyltransferase, CAAX box, beta |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| FUZ | fuzzy planar cell polarity protein |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
| GATB | glutamyl-tRNA(Gln) amidotransferase, subunit B |
| GDAP1 | ganglioside induced differentiation associated protein 1 |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GPX2 | glutathione peroxidase 2 |
| HIST1H2BC | histone cluster 1, H2bc |
| HPSE | heparanase |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| IL17RA | interleukin 17 receptor A |
| INO80D | INO80 complex subunit D |
| LAMA3 | laminin, alpha 3 |
| LYRM9 | LYR motif containing 9 |
| MBIP | MAP3K12 binding inhibitory protein 1 |
| MBTD1 | mbt domain containing 1 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| METTL16 | methyltransferase like 16 |
| MICALL2 | MICAL-like 2 |
| MIS18BP1 | MIS18 binding protein 1 |
| MORC4 | MORC family CW-type zinc finger 4 |
| MOSPD3 | motile sperm domain containing 3 |
| MTHFS | 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) |
| MTMR11 | myotubularin related protein 11 |
| MUTYH | mutY homolog |
| NCAM2 | neural cell adhesion molecule 2 |
| NECAB3 | N-terminal EF-hand calcium binding protein 3 |
| NES | nestin |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| OSMR | oncostatin M receptor |
| PARD6A | par-6 family cell polarity regulator alpha |
| PARPBP | PARP1 binding protein |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PGGT1B | protein geranylgeranyltransferase type I, beta subunit |
| PLD3 | phospholipase D family, member 3 |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RBM41 | RNA binding motif protein 41 |
| RFTN1 | raftlin, lipid raft linker 1 |
| SECTM1 | secreted and transmembrane 1 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SND1-IT1 | SND1 intronic transcript 1 |
| SNRPC | small nuclear ribonucleoprotein polypeptide C |
| SPIDR | scaffolding protein involved in DNA repair |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) |
| SYTL2 | synaptotagmin-like 2 |
| TAF1A | TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa |
| TCTA | T-cell leukemia translocation altered |
| TCTN2 | tectonic family member 2 |
| THOP1 | thimet oligopeptidase 1 |
| TLN1 | talin 1 |
| TOE1 | target of EGR1, member 1 (nuclear) |
| TPST2 | tyrosylprotein sulfotransferase 2 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein |
| TSPAN1 | tetraspanin 1 |
| TXLNG | taxilin gamma |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZFP30 | ZFP30 zinc finger protein |
| ZNF211 | zinc finger protein 211 |
| ZNF586 | zinc finger protein 586 |
| ZNF747 | zinc finger protein 747 |
| ZNF767P | zinc finger family member 767, pseudogene |
