naltriben-mesylate Gene Set

Dataset LINCS L1000 CMAP Chemical Perturbation Consensus Signatures
Category transcriptomics
Type small molecule perturbation
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Genes

618 genes differentially expressed following the naltriben-mesylate small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
EPHB2 EPH receptor B2 6.83399
PFKL phosphofructokinase, liver 6.59257
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1 5.92238
CACNB2 calcium channel, voltage-dependent, beta 2 subunit 5.76622
CASP4 caspase 4, apoptosis-related cysteine peptidase 5.60555
CDHR1 cadherin-related family member 1 5.58717
DDR1 discoidin domain receptor tyrosine kinase 1 5.41855
CA11 carbonic anhydrase XI 5.35543
WNT3 wingless-type MMTV integration site family, member 3 5.32616
DUSP22 dual specificity phosphatase 22 5.25007
DEPDC5 DEP domain containing 5 5.19259
ZBED2 zinc finger, BED-type containing 2 5.16601
TBXA2R thromboxane A2 receptor 5.14111
SNX10 sorting nexin 10 5.07461
ADCK2 aarF domain containing kinase 2 5.06864
NRTN neurturin 4.92881
NDUFC1 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa 4.88369
FAIM Fas apoptotic inhibitory molecule 4.79815
APOLD1 apolipoprotein L domain containing 1 4.78009
TMEM74B transmembrane protein 74B 4.77243
FNBP1L formin binding protein 1-like 4.74751
CSNK2A2 casein kinase 2, alpha prime polypeptide 4.73179
MOS v-mos Moloney murine sarcoma viral oncogene homolog 4.69553
GPA33 glycoprotein A33 (transmembrane) 4.65234
FAM76A family with sequence similarity 76, member A 4.62538
LYST lysosomal trafficking regulator 4.61906
IL18 interleukin 18 4.61636
PFDN4 prefoldin subunit 4 4.611
PEX2 peroxisomal biogenesis factor 2 4.60802
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 4.58717
HOXA4 homeobox A4 4.54377
FBXO2 F-box protein 2 4.49634
GSTT1 glutathione S-transferase theta 1 4.48336
IL2 interleukin 2 4.48331
CCR6 chemokine (C-C motif) receptor 6 4.45515
NRCAM neuronal cell adhesion molecule 4.44942
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 4.43243
COBL cordon-bleu WH2 repeat protein 4.42792
TPPP3 tubulin polymerization-promoting protein family member 3 4.4066
UQCRB ubiquinol-cytochrome c reductase binding protein 4.39388
CEP70 centrosomal protein 70kDa 4.37745
RPA4 replication protein A4, 30kDa 4.34332
EXT2 exostosin glycosyltransferase 2 4.31319
ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2 4.2148
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 4.20814
PRDX2 peroxiredoxin 2 4.20457
CFDP1 craniofacial development protein 1 4.2014
CXADR coxsackie virus and adenovirus receptor 4.19993
SPTLC2 serine palmitoyltransferase, long chain base subunit 2 4.14886
LRP3 low density lipoprotein receptor-related protein 3 4.14502
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) 4.13973
CEP57 centrosomal protein 57kDa 4.13768
GPR88 G protein-coupled receptor 88 4.13378
ACBD4 acyl-CoA binding domain containing 4 4.12212
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 4.1031
DLX4 distal-less homeobox 4 4.09621
RAB17 RAB17, member RAS oncogene family 4.09109
UBA2 ubiquitin-like modifier activating enzyme 2 4.08013
SNX29 sorting nexin 29 4.07203
UPF3B UPF3 regulator of nonsense transcripts homolog B (yeast) 4.06904
AKAP8 A kinase (PRKA) anchor protein 8 4.06498
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit 4.05467
DUSP2 dual specificity phosphatase 2 4.05453
GUCY2C guanylate cyclase 2C 4.05169
WWOX WW domain containing oxidoreductase 4.03772
IL21R interleukin 21 receptor 4.03296
IL17A interleukin 17A 4.03207
MAGEB1 melanoma antigen family B1 4.03069
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase 4.02745
UTS2 urotensin 2 4.0257
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 4.01174
CD1C CD1c molecule 4.00217
WDR7 WD repeat domain 7 3.98583
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit 3.96417
CIAO2B cytosolic iron-sulfur assembly component 2B 3.9634
RBM42 RNA binding motif protein 42 3.95743
TMEM255A transmembrane protein 255A 3.94201
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 3.94097
DIAPH2 diaphanous-related formin 2 3.92706
TBCA tubulin folding cofactor A 3.9102
GLI2 GLI family zinc finger 2 3.90677
CD1A CD1a molecule 3.9038
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa 3.90097
APLP1 amyloid beta (A4) precursor-like protein 1 3.89325
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B 3.88823
NEK9 NIMA-related kinase 9 3.86593
PNLIPRP2 pancreatic lipase-related protein 2 3.86505
CHMP2B charged multivesicular body protein 2B 3.86457
ZDHHC8BP ZDHHC8B, pseudogene 3.85535
CTAG2 cancer/testis antigen 2 3.84058
NBN nibrin 3.83661
NR1I2 nuclear receptor subfamily 1, group I, member 2 3.78348
F2RL2 coagulation factor II (thrombin) receptor-like 2 3.78109
GBX1 gastrulation brain homeobox 1 3.77918
SFI1 Sfi1 homolog, spindle assembly associated (yeast) 3.77597
PCDHA5 protocadherin alpha 5 3.77225
CDKN2A cyclin-dependent kinase inhibitor 2A 3.76778
SLA Src-like-adaptor 3.76257
GRAMD4 GRAM domain containing 4 3.75831
FLT4 fms-related tyrosine kinase 4 3.74701
HNRNPR heterogeneous nuclear ribonucleoprotein R 3.74428
TCIM transcriptional and immune response regulator 3.74423
PTH parathyroid hormone 3.74082
ZNF446 zinc finger protein 446 3.73557
GSTZ1 glutathione S-transferase zeta 1 3.73446
ADCY3 adenylate cyclase 3 3.73234
KRT8 keratin 8, type II 3.71802
PLAGL1 pleiomorphic adenoma gene-like 1 3.71537
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 3.70388
COL5A2 collagen, type V, alpha 2 3.70329
IKZF3 IKAROS family zinc finger 3 (Aiolos) 3.69935
TEX12 testis expressed 12 3.68101
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 3.66325
HMHB1 histocompatibility (minor) HB-1 3.65487
MAGEC2 melanoma antigen family C2 3.65344
TASL TLR adaptor interacting with endolysosomal SLC15A4 3.65244
TCF20 transcription factor 20 (AR1) 3.64503
EMID1 EMI domain containing 1 3.64478
TULP1 tubby like protein 1 3.62684
PDE2A phosphodiesterase 2A, cGMP-stimulated 3.62429
MAGEA12 melanoma antigen family A12 3.6154
GSTA3 glutathione S-transferase alpha 3 3.61303
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) 3.61001
KRT85 keratin 85, type II 3.60721
DNAL4 dynein, axonemal, light chain 4 3.60227
EPPK1 epiplakin 1 3.60079
KRT75 keratin 75, type II 3.5992
NSF N-ethylmaleimide-sensitive factor 3.59787
TRAPPC6A trafficking protein particle complex 6A 3.59181
AVL9 AVL9 homolog (S. cerevisiase) 3.58943
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 3.58226
CASP1 caspase 1, apoptosis-related cysteine peptidase 3.57873
KALRN kalirin, RhoGEF kinase 3.57589
ZFR zinc finger RNA binding protein 3.56844
PACRG PARK2 co-regulated 3.56644
TMEM147 transmembrane protein 147 3.56117
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1 3.55225
ZNF318 zinc finger protein 318 3.54777
HTRA1 HtrA serine peptidase 1 3.53509
EYA4 EYA transcriptional coactivator and phosphatase 4 3.52656
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) 3.52166
ALPI alkaline phosphatase, intestinal 3.51247
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 3.51217
CASS4 Cas scaffolding protein family member 4 3.50884
SV2A synaptic vesicle glycoprotein 2A 3.50648
MAGEB2 melanoma antigen family B2 3.50615
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) 3.50333
ZNF780B zinc finger protein 780B 3.49909
CLIP2 CAP-GLY domain containing linker protein 2 3.49678
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein 3.49462
NXPH4 neurexophilin 4 3.49359
CPA2 carboxypeptidase A2 (pancreatic) 3.49224
FTO fat mass and obesity associated 3.492
CAMTA2 calmodulin binding transcription activator 2 3.48986
NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) 3.47783
PATZ1 POZ (BTB) and AT hook containing zinc finger 1 3.47278
GPATCH1 G patch domain containing 1 3.47151
MYOF myoferlin 3.46255
POMT2 protein-O-mannosyltransferase 2 3.45595
SDCBP syndecan binding protein (syntenin) 3.45548
PCDH17 protocadherin 17 3.45246
LAMB4 laminin, beta 4 3.44597
LGALS9 lectin, galactoside-binding, soluble, 9 3.44565
REX1BD required for excision 1-B domain containing 3.4452
NLGN4X neuroligin 4, X-linked 3.43711
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 3.43654
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila) 3.43416
IL3 interleukin 3 3.43061
CFLAR CASP8 and FADD-like apoptosis regulator 3.42724
HOXB7 homeobox B7 3.42461
NOS2 nitric oxide synthase 2, inducible 3.42206
SPINT1 serine peptidase inhibitor, Kunitz type 1 3.41333
SIK1 salt-inducible kinase 1 3.41227
CHMP2A charged multivesicular body protein 2A 3.40852
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 3.40634
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2 3.40571
LIG3 ligase III, DNA, ATP-dependent 3.40456
PANX1 pannexin 1 3.40251
MAGEA3 melanoma antigen family A3 3.39785
GNB5 guanine nucleotide binding protein (G protein), beta 5 3.39506
TBC1D22A TBC1 domain family, member 22A 3.38893
PHKA2 phosphorylase kinase, alpha 2 (liver) 3.38186
KPNA1 karyopherin alpha 1 (importin alpha 5) 3.38031
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 3.37746
CSPG4 chondroitin sulfate proteoglycan 4 3.37637
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X 3.37457
SIRT6 sirtuin 6 3.36891
FGFR3 fibroblast growth factor receptor 3 3.36855
LOXL2 lysyl oxidase-like 2 3.35894
FOXI1 forkhead box I1 3.35389
NPHP4 nephronophthisis 4 3.35376
HOOK1 hook microtubule-tethering protein 1 3.3501
SLIT2 slit homolog 2 (Drosophila) 3.34953
ZNF177 zinc finger protein 177 3.34676
SORBS3 sorbin and SH3 domain containing 3 3.34566
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3 3.34389
SPAG1 sperm associated antigen 1 3.33403
HLA-DMA major histocompatibility complex, class II, DM alpha 3.33336
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 3.31419
MEIS1 Meis homeobox 1 3.30709
CARTPT CART prepropeptide 3.30613
RAB31 RAB31, member RAS oncogene family 3.30598
ARID5B AT rich interactive domain 5B (MRF1-like) 3.30247
CD207 CD207 molecule, langerin 3.30194
CCDC198 coiled-coil domain containing 198 3.30181
NDUFA6 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa 3.29882
CA12 carbonic anhydrase XII 3.29867
HIC2 hypermethylated in cancer 2 3.29772
OLA1 Obg-like ATPase 1 3.29378
CEP83 centrosomal protein 83kDa 3.28586
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 3.28526
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 3.26879
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta 3.26649
CLIP3 CAP-GLY domain containing linker protein 3 3.26122
COX6C cytochrome c oxidase subunit VIc 3.26051
RBM28 RNA binding motif protein 28 3.2556
SLC35F2 solute carrier family 35, member F2 3.24944
TAS2R3 taste receptor, type 2, member 3 3.24877
KRT34 keratin 34, type I 3.24554
R3HDM4 R3H domain containing 4 3.24282
LY6H lymphocyte antigen 6 complex, locus H 3.23197
TRPC2 transient receptor potential cation channel, subfamily C, member 2, pseudogene 3.22896
GAGE1 G antigen 1 3.21721
ADGB androglobin 3.21545
ADTRP androgen-dependent TFPI-regulating protein 3.21357
STAMBPL1 STAM binding protein-like 1 3.21313
ZDHHC13 zinc finger, DHHC-type containing 13 3.20942
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5 3.20258
ACO2 aconitase 2, mitochondrial 3.19973
COL9A3 collagen, type IX, alpha 3 3.19969
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae) 3.19831
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 3.18975
NSFL1C NSFL1 (p97) cofactor (p47) 3.18749
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa 3.18741
NDUFB2 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa 3.18539
ATP6V0E2 ATPase, H+ transporting V0 subunit e2 3.18211
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7 3.17726
ACD adrenocortical dysplasia homolog (mouse) 3.17322
SUN1 Sad1 and UNC84 domain containing 1 3.17307
DNM1L dynamin 1-like 3.15281
CD99 CD99 molecule 3.14438
TMPRSS15 transmembrane protease, serine 15 3.14367
RNF126P1 ring finger protein 126 pseudogene 1 3.14243
IFT57 intraflagellar transport 57 3.14204
CCDC81 coiled-coil domain containing 81 3.14027
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 3.13733
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 3.1363
DLG2 discs, large homolog 2 (Drosophila) 3.13427
SQOR sulfide quinone oxidoreductase 3.13217
ANKMY1 ankyrin repeat and MYND domain containing 1 3.1223
CFAP46 cilia and flagella associated protein 46 3.12059
PRR13 proline rich 13 3.11844
RTN1 reticulon 1 3.11681
SSX7 synovial sarcoma, X breakpoint 7 3.1064
KRT84 keratin 84, type II 3.10625
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7 3.10525
GSAP gamma-secretase activating protein 3.10317
GJA3 gap junction protein, alpha 3, 46kDa 3.10303
DPM1 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit 3.10244
GK3 glycerol kinase 3 3.09524
UNC93A unc-93 homolog A (C. elegans) 3.09509
NCOA6 nuclear receptor coactivator 6 3.09403
PWP2 PWP2 periodic tryptophan protein homolog (yeast) 3.0912
MYO1A myosin IA 3.09096
NOX1 NADPH oxidase 1 3.08856
AMPD3 adenosine monophosphate deaminase 3 3.08057
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F 3.07614
TRRAP transformation/transcription domain-associated protein 3.06591
CPLANE2 ciliogenesis and planar polarity effector complex subunit 2 3.06411
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit 3.06272
NEO1 neogenin 1 3.06226
SERINC3 serine incorporator 3 3.06087
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor 3.05968
STAT5A signal transducer and activator of transcription 5A 3.05917
HIP1 huntingtin interacting protein 1 3.05659
INSL4 insulin-like 4 (placenta) 3.05578
GYPE glycophorin E (MNS blood group) 3.05185
GDF9 growth differentiation factor 9 3.05007
COX17 COX17 cytochrome c oxidase copper chaperone 3.04983
DYNLRB1 dynein, light chain, roadblock-type 1 3.04647
TLCD3A TLC domain containing 3A 3.03308
TTC33 tetratricopeptide repeat domain 33 3.03299
LIMK2 LIM domain kinase 2 3.03004
MDM4 MDM4, p53 regulator 3.02685
GRIA2 glutamate receptor, ionotropic, AMPA 2 3.0264
TTC12 tetratricopeptide repeat domain 12 3.0261
RPS2 ribosomal protein S2 3.02101
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 3.01906
GP6 glycoprotein VI (platelet) 3.0175
RTCB RNA 2',3'-cyclic phosphate and 5'-OH ligase 3.01632
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4 3.016
LRRC32 leucine rich repeat containing 32 3.01336
SUGP1 SURP and G patch domain containing 1 3.00666
SYF2 SYF2 pre-mRNA-splicing factor 3.00564
IL10 interleukin 10 3.00511
CBS cystathionine-beta-synthase 3.0038
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 3.0021

decreased expression

Symbol Name Standardized Value
TERT telomerase reverse transcriptase -7.44679
PPP1R13B protein phosphatase 1, regulatory subunit 13B -7.17482
RFX5 regulatory factor X, 5 (influences HLA class II expression) -6.65605
IFNAR1 interferon (alpha, beta and omega) receptor 1 -6.63583
UBAP1 ubiquitin associated protein 1 -6.62702
CASP10 caspase 10, apoptosis-related cysteine peptidase -6.11382
MC4R melanocortin 4 receptor -5.78035
H2AZ2 H2A.Z variant histone 2 -5.61066
ITGB1BP1 integrin beta 1 binding protein 1 -5.5961
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 -5.54469
CMPK1 cytidine monophosphate (UMP-CMP) kinase 1, cytosolic -5.49071
TIMM23 translocase of inner mitochondrial membrane 23 homolog (yeast) -5.45659
POLR1C polymerase (RNA) I polypeptide C, 30kDa -5.36071
HAUS6 HAUS augmin-like complex, subunit 6 -5.33152
GTDC1 glycosyltransferase-like domain containing 1 -5.18916
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2 -5.17455
FBXW11 F-box and WD repeat domain containing 11 -4.99014
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase -4.96432
GPRC5D G protein-coupled receptor, class C, group 5, member D -4.92902
BCAS1 breast carcinoma amplified sequence 1 -4.85033
ANXA10 annexin A10 -4.82442
REEP5 receptor accessory protein 5 -4.79939
GPBP1L1 GC-rich promoter binding protein 1-like 1 -4.70801
YY1 YY1 transcription factor -4.66972
PALS1 protein associated with LIN7 1, MAGUK p55 family member -4.61541
ALAD aminolevulinate dehydratase -4.58136
CCP110 centriolar coiled coil protein 110kDa -4.56354
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -4.56083
RABIF RAB interacting factor -4.55788
MIA3 melanoma inhibitory activity family, member 3 -4.53429
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A -4.51494
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3 -4.4925
FABP3 fatty acid binding protein 3, muscle and heart -4.48541
TMEM223 transmembrane protein 223 -4.47805
TDRKH tudor and KH domain containing -4.47275
MARK3 MAP/microtubule affinity-regulating kinase 3 -4.46336
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 -4.4462
RRH retinal pigment epithelium-derived rhodopsin homolog -4.39438
CCDC57 coiled-coil domain containing 57 -4.3815
RABL3 RAB, member of RAS oncogene family-like 3 -4.36617
MAP2K5 mitogen-activated protein kinase kinase 5 -4.35082
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae) -4.34189
ABRAXAS2 abraxas 2, BRISC complex subunit -4.31511
AOC3 amine oxidase, copper containing 3 -4.30752
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase -4.28765
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa -4.26812
TOR1A torsin family 1, member A (torsin A) -4.24515
COLEC11 collectin sub-family member 11 -4.2386
MT2A metallothionein 2A -4.23563
PCYOX1 prenylcysteine oxidase 1 -4.22559
RMND5B required for meiotic nuclear division 5 homolog B (S. cerevisiae) -4.2237
ABCD2 ATP-binding cassette, sub-family D (ALD), member 2 -4.21971
MERTK MER proto-oncogene, tyrosine kinase -4.20633
CCSER2 coiled-coil serine-rich protein 2 -4.20592
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1 -4.1406
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit -4.13515
FHOD3 formin homology 2 domain containing 3 -4.11825
KRT5 keratin 5, type II -4.11744
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 -4.11284
KNTC1 kinetochore associated 1 -4.11053
CALCA calcitonin-related polypeptide alpha -4.08135
SAMD9 sterile alpha motif domain containing 9 -4.06693
TRPV1 transient receptor potential cation channel, subfamily V, member 1 -4.06103
GPR39 G protein-coupled receptor 39 -4.05278
CAB39L calcium binding protein 39-like -4.04548
STIL SCL/TAL1 interrupting locus -4.04154
FAT2 FAT atypical cadherin 2 -4.02541
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit -3.98596
UBE2D4 ubiquitin-conjugating enzyme E2D 4 (putative) -3.96908
ZFR2 zinc finger RNA binding protein 2 -3.96489
PEX11B peroxisomal biogenesis factor 11 beta -3.93578
SCN4A sodium channel, voltage gated, type IV alpha subunit -3.93521
NUDT7 nudix (nucleoside diphosphate linked moiety X)-type motif 7 -3.90448
UBE2G1 ubiquitin-conjugating enzyme E2G 1 -3.89951
EFCAB14 EF-hand calcium binding domain 14 -3.89573
RAB29 RAB29, member RAS oncogene family -3.8872
PCCB propionyl CoA carboxylase, beta polypeptide -3.87602
GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble) -3.86379
STX17 syntaxin 17 -3.85009
CCDC69 coiled-coil domain containing 69 -3.84714
MME membrane metallo-endopeptidase -3.84422
TMX2 thioredoxin-related transmembrane protein 2 -3.83974
POLR3F polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa -3.83285
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 -3.82608
RFC3 replication factor C (activator 1) 3, 38kDa -3.82167
INHA inhibin, alpha -3.8216
IPO13 importin 13 -3.81957
TSLIG3A tRNA splicing ligase complex subunit 3A -3.8077
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 -3.80636
PCDHA2 protocadherin alpha 2 -3.78857
BTD biotinidase -3.7814
BUB3 BUB3 mitotic checkpoint protein -3.77605
CNMD chondromodulin -3.77111
CALB2 calbindin 2 -3.76465
CADPS2 Ca++-dependent secretion activator 2 -3.74692
PRELID3A PRELI domain containing 3A -3.74108
BPHL biphenyl hydrolase-like (serine hydrolase) -3.73898
NSD2 nuclear receptor binding SET domain protein 2 -3.7332
MTMR10 myotubularin related protein 10 -3.72603
WDR55 WD repeat domain 55 -3.71536
ENSA endosulfine alpha -3.71411
WNT10B wingless-type MMTV integration site family, member 10B -3.71222
LINC01565 long intergenic non-protein coding RNA 1565 -3.68834
PARG poly (ADP-ribose) glycohydrolase -3.68803
TSPYL5 TSPY-like 5 -3.67432
TIMP1 TIMP metallopeptidase inhibitor 1 -3.67144
TNS1 tensin 1 -3.66984
LHFPL6 LHFPL tetraspan subfamily member 6 -3.66562
DRD3 dopamine receptor D3 -3.64995
TOGARAM1 TOG array regulator of axonemal microtubules 1 -3.6469
LDB3 LIM domain binding 3 -3.64592
POLH polymerase (DNA directed), eta -3.6378
OTOR otoraplin -3.63248
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein -3.61991
OR2H2 olfactory receptor, family 2, subfamily H, member 2 -3.61965
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria -3.61944
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 -3.61481
SNAPC3 small nuclear RNA activating complex, polypeptide 3, 50kDa -3.60623
RARS1 arginyl-tRNA synthetase 1 -3.59945
PDCL phosducin-like -3.59422
CYB561 cytochrome b561 -3.5936
SLC2A4RG SLC2A4 regulator -3.58527
ELK4 ELK4, ETS-domain protein (SRF accessory protein 1) -3.58269
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor -3.58228
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha -3.5752
RASL11B RAS-like, family 11, member B -3.56955
AKR1C2 aldo-keto reductase family 1, member C2 -3.56909
MYO16 myosin XVI -3.56904
PSIP1 PC4 and SFRS1 interacting protein 1 -3.56062
CD38 CD38 molecule -3.53373
TMEM165 transmembrane protein 165 -3.51929
SLC38A2 solute carrier family 38, member 2 -3.5143
MT1X metallothionein 1X -3.51146
TFF2 trefoil factor 2 -3.49999
PLK4 polo-like kinase 4 -3.4935
KLHL21 kelch-like family member 21 -3.48687
H2AJ H2A.J histone -3.48483
PSME4 proteasome (prosome, macropain) activator subunit 4 -3.48483
RB1 retinoblastoma 1 -3.48445
UBE4B ubiquitination factor E4B -3.48387
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4 -3.48103
AQP7 aquaporin 7 -3.47284
SLC13A3 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 -3.47148
PLEKHA6 pleckstrin homology domain containing, family A member 6 -3.46782
TREM1 triggering receptor expressed on myeloid cells 1 -3.46665
MYOC myocilin, trabecular meshwork inducible glucocorticoid response -3.45719
TXNDC9 thioredoxin domain containing 9 -3.45677
DPYSL3 dihydropyrimidinase-like 3 -3.45009
AQP5 aquaporin 5 -3.44961
MIA melanoma inhibitory activity -3.44922
AKR1C1 aldo-keto reductase family 1, member C1 -3.44659
ERMP1 endoplasmic reticulum metallopeptidase 1 -3.44497
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3 -3.44014
LEP leptin -3.43678
TRIM24 tripartite motif containing 24 -3.4215
PAGE4 P antigen family, member 4 (prostate associated) -3.4197
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta -3.41815
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) -3.41357
OGFRL1 opioid growth factor receptor-like 1 -3.4134
EPHA7 EPH receptor A7 -3.41302
ZNF415 zinc finger protein 415 -3.3997
ADRA2A adrenoceptor alpha 2A -3.39887
TBC1D4 TBC1 domain family, member 4 -3.39372
ENO3 enolase 3 (beta, muscle) -3.38935
BTBD7 BTB (POZ) domain containing 7 -3.38639
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 -3.38395
RNF31 ring finger protein 31 -3.38196
ERVMER34-1 endogenous retrovirus group MER34, member 1 -3.3735
IFT22 intraflagellar transport 22 -3.3553
LRRN3 leucine rich repeat neuronal 3 -3.35053
NQO1 NAD(P)H dehydrogenase, quinone 1 -3.3498
TRPM1 transient receptor potential cation channel, subfamily M, member 1 -3.34964
NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) -3.34908
MATN2 matrilin 2 -3.34901
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 -3.34737
MSMB microseminoprotein, beta- -3.34548
HGD homogentisate 1,2-dioxygenase -3.34301
LMAN1L lectin, mannose-binding, 1 like -3.34284
PLXNB3 plexin B3 -3.34179
POPDC3 popeye domain containing 3 -3.3392
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled -3.33059
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 -3.32885
ZC3HAV1 zinc finger CCCH-type, antiviral 1 -3.32602
NKX2-8 NK2 homeobox 8 -3.32542
RPS11 ribosomal protein S11 -3.32308
KRT14 keratin 14, type I -3.32132
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1 -3.31929
ARMC9 armadillo repeat containing 9 -3.31185
FAM114A1 family with sequence similarity 114, member A1 -3.31097
AMOT angiomotin -3.31054
TUBA1B tubulin, alpha 1b -3.30657
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 -3.30649
CAMK2G calcium/calmodulin-dependent protein kinase II gamma -3.30639
ORC3 origin recognition complex, subunit 3 -3.29971
ATP5F1A ATP synthase F1 subunit alpha -3.29656
AK4 adenylate kinase 4 -3.29501
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 -3.28823
CNOT6 CCR4-NOT transcription complex, subunit 6 -3.28764
HBS1L HBS1-like translational GTPase -3.2777
STIP1 stress-induced phosphoprotein 1 -3.27353
REC8 REC8 meiotic recombination protein -3.27168
STEAP1 six transmembrane epithelial antigen of the prostate 1 -3.26827
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 -3.26549
IL18BP interleukin 18 binding protein -3.26333
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa -3.25847
DHFR dihydrofolate reductase -3.25729
SNX7 sorting nexin 7 -3.25715
ACTR8 ARP8 actin-related protein 8 homolog (yeast) -3.25696
RHOBTB1 Rho-related BTB domain containing 1 -3.25577
DENND1B DENN/MADD domain containing 1B -3.25432
MEFV Mediterranean fever -3.25076
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled -3.24932
HJURP Holliday junction recognition protein -3.24509
COX15 cytochrome c oxidase assembly homolog 15 (yeast) -3.23914
POLQ polymerase (DNA directed), theta -3.23458
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5 -3.2342
SGCA sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein) -3.23386
RGS17 regulator of G-protein signaling 17 -3.23088
GFPT1 glutamine--fructose-6-phosphate transaminase 1 -3.22836
LIAS lipoic acid synthetase -3.22835
AKR1C3 aldo-keto reductase family 1, member C3 -3.22578
FOLH1B folate hydrolase 1B -3.2253
ABI2 abl-interactor 2 -3.22148
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C -3.22131
FBXL4 F-box and leucine-rich repeat protein 4 -3.20764
MED8 mediator complex subunit 8 -3.20732
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form) -3.20299
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa -3.20218
ARPC5L actin related protein 2/3 complex, subunit 5-like -3.20191
SLC45A2 solute carrier family 45, member 2 -3.20164
ZNF85 zinc finger protein 85 -3.19968
TRNAU1AP tRNA selenocysteine 1 associated protein 1 -3.19932
MT1HL1 metallothionein 1H-like 1 -3.19667
UBAP2 ubiquitin associated protein 2 -3.19647
BRCA2 breast cancer 2, early onset -3.19462
TAGLN3 transgelin 3 -3.19226
FBXO28 F-box protein 28 -3.18968
LRRC20 leucine rich repeat containing 20 -3.1887
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon -3.18847
RPL23AP7 ribosomal protein L23a pseudogene 7 -3.18309
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) -3.18259
HLA-E major histocompatibility complex, class I, E -3.18013
MCM6 minichromosome maintenance complex component 6 -3.17603
C3ORF36 chromosome 3 open reading frame 36 -3.17574
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4 -3.17511
MCM10 minichromosome maintenance complex component 10 -3.1751
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila) -3.17465
TACR2 tachykinin receptor 2 -3.17273
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16 -3.17199
SS18L1 synovial sarcoma translocation gene on chromosome 18-like 1 -3.17083
MRPS27 mitochondrial ribosomal protein S27 -3.16891
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 -3.16891
MLXIP MLX interacting protein -3.1685
BCL2 B-cell CLL/lymphoma 2 -3.16665
NAA40 N(alpha)-acetyltransferase 40, NatD catalytic subunit -3.16319
KLHL12 kelch-like family member 12 -3.16272
ARMCX6 armadillo repeat containing, X-linked 6 -3.15775
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae) -3.15634
RASAL1 RAS protein activator like 1 (GAP1 like) -3.15595
MUC7 mucin 7, secreted -3.15182
COLEC10 collectin sub-family member 10 (C-type lectin) -3.14914
ENTREP1 endosomal transmembrane epsin interactor 1 -3.14798
MYOM2 myomesin 2 -3.14775
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b -3.14567
TRIT1 tRNA isopentenyltransferase 1 -3.14133
ENOSF1 enolase superfamily member 1 -3.13982
ZWILCH zwilch kinetochore protein -3.12743
MAPK13 mitogen-activated protein kinase 13 -3.12532
FAM110D family with sequence similarity 110, member D -3.12434
PKP1 plakophilin 1 -3.12396
ITGB1BP2 integrin beta 1 binding protein (melusin) 2 -3.1224
TINAGL1 tubulointerstitial nephritis antigen-like 1 -3.12014
LTK leukocyte receptor tyrosine kinase -3.11877
ATRNL1 attractin-like 1 -3.11712
AMPD1 adenosine monophosphate deaminase 1 -3.11655
TTC9 tetratricopeptide repeat domain 9 -3.11309
PORCN porcupine homolog (Drosophila) -3.10779
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 -3.10469
ALDH8A1 aldehyde dehydrogenase 8 family, member A1 -3.10214
LHFPL2 lipoma HMGIC fusion partner-like 2 -3.10168
SLAMF7 SLAM family member 7 -3.0945
DNA2 DNA replication helicase/nuclease 2 -3.08848
VPS33B vacuolar protein sorting 33 homolog B (yeast) -3.08838
ACSM3 acyl-CoA synthetase medium-chain family member 3 -3.08635
TOE1 target of EGR1, member 1 (nuclear) -3.08498
MRPL58 mitochondrial ribosomal protein L58 -3.08203
RAP2A RAP2A, member of RAS oncogene family -3.08145
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 -3.08139
FAT4 FAT atypical cadherin 4 -3.07844
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6 -3.07534
TUBB6 tubulin, beta 6 class V -3.07521
CUX2 cut-like homeobox 2 -3.07246
LINC02249 long intergenic non-protein coding RNA 2249 -3.06955
F11R F11 receptor -3.06942
TRAK2 trafficking protein, kinesin binding 2 -3.06678
HELLS helicase, lymphoid-specific -3.06602
BBS10 Bardet-Biedl syndrome 10 -3.06492
FAM163A family with sequence similarity 163, member A -3.06135
PLXNC1 plexin C1 -3.06006
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog -3.0582
SBNO1 strawberry notch homolog 1 (Drosophila) -3.05476
PYGM phosphorylase, glycogen, muscle -3.05435
CDC37L1 cell division cycle 37-like 1 -3.05101
CKAP2 cytoskeleton associated protein 2 -3.04783
CTNNA3 catenin (cadherin-associated protein), alpha 3 -3.04628
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene -3.04569
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B -3.04125
PPIEL peptidylprolyl isomerase E-like pseudogene -3.03596
ASF1A anti-silencing function 1A histone chaperone -3.03338
SYNE3 spectrin repeat containing, nuclear envelope family member 3 -3.03301
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 -3.0327
ADI1 acireductone dioxygenase 1 -3.03226
NTAN1 N-terminal asparagine amidase -3.03105
SPRYD7 SPRY domain containing 7 -3.02807
PRDX3 peroxiredoxin 3 -3.02669
CD2AP CD2-associated protein -3.02583
SLC30A4 solute carrier family 30 (zinc transporter), member 4 -3.02313
SHB Src homology 2 domain containing adaptor protein B -3.02261
GPATCH2 G patch domain containing 2 -3.01148
GSTT2 glutathione S-transferase theta 2 (gene/pseudogene) -3.00196
LINC00472 long intergenic non-protein coding RNA 472 -3.00089