napelline-2522 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the napelline-2522 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
AFF2 AF4/FMR2 family, member 2
AGGF1 angiogenic factor with G patch and FHA domains 1
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ANXA9 annexin A9
APC adenomatous polyposis coli
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2
ARMCX4 armadillo repeat containing, X-linked 4
BAZ2A bromodomain adjacent to zinc finger domain, 2A
C11ORF63 chromosome 11 open reading frame 63
C17ORF53 chromosome 17 open reading frame 53
C6ORF10 chromosome 6 open reading frame 10
CALD1 caldesmon 1
CAPN5 calpain 5
CCDC181 coiled-coil domain containing 181
COL10A1 collagen, type X, alpha 1
COL4A1 collagen, type IV, alpha 1
COL6A1 collagen, type VI, alpha 1
CRP C-reactive protein, pentraxin-related
CTNNA2 catenin (cadherin-associated protein), alpha 2
DAGLA diacylglycerol lipase, alpha
DDO D-aspartate oxidase
DGCR5 DiGeorge syndrome critical region gene 5 (non-protein coding)
DHRS7 dehydrogenase/reductase (SDR family) member 7
DLC1 DLC1 Rho GTPase activating protein
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DST dystonin
DSTYK dual serine/threonine and tyrosine protein kinase
EGFR epidermal growth factor receptor
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
EPB41L4B erythrocyte membrane protein band 4.1 like 4B
EPYC epiphycan
F12 coagulation factor XII (Hageman factor)
GCNT4 glucosaminyl (N-acetyl) transferase 4, core 2
GNAL guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
GPR137 G protein-coupled receptor 137
GSN-AS1 GSN antisense RNA 1
GSTA1 glutathione S-transferase alpha 1
HFE hemochromatosis
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IFNW1 interferon, omega 1
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IL1RN interleukin 1 receptor antagonist
KIF24 kinesin family member 24
KLK7 kallikrein-related peptidase 7
KLRF1 killer cell lectin-like receptor subfamily F, member 1
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LHX2 LIM homeobox 2
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
LMF1 lipase maturation factor 1
LOC100131510 uncharacterized LOC100131510
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1
MCF2 MCF.2 cell line derived transforming sequence
NCKAP1 NCK-associated protein 1
NEU3 sialidase 3 (membrane sialidase)
NEUROD6 neuronal differentiation 6
NMUR1 neuromedin U receptor 1
NOS1 nitric oxide synthase 1 (neuronal)
NPR3 natriuretic peptide receptor 3
NRL neural retina leucine zipper
NRXN1 neurexin 1
OSBP2 oxysterol binding protein 2
PDLIM3 PDZ and LIM domain 3
PIK3C2G phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma
PLXDC1 plexin domain containing 1
PLXNC1 plexin C1
PMEPA1 prostate transmembrane protein, androgen induced 1
POU5F1P3 POU class 5 homeobox 1 pseudogene 3
PRAMEF11 PRAME family member 11
PRKCA protein kinase C, alpha
PRKCZ protein kinase C, zeta
PROX1 prospero homeobox 1
PTGIR prostaglandin I2 (prostacyclin) receptor (IP)
PTTG2 pituitary tumor-transforming 2
PVR poliovirus receptor
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SH2D3A SH2 domain containing 3A
SMR3B submaxillary gland androgen regulated protein 3B
SOCS3 suppressor of cytokine signaling 3
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
SYT1 synaptotagmin I
TAGLN3 transgelin 3
TBX5 T-box 5
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFR2 transferrin receptor 2
TRO trophinin
TSKU tsukushi, small leucine rich proteoglycan
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17
WNT2 wingless-type MMTV integration site family member 2
WWTR1 WW domain containing transcription regulator 1
ZBTB17 zinc finger and BTB domain containing 17
ZER1 zyg-11 related, cell cycle regulator
ZNF205 zinc finger protein 205
ZNF337 zinc finger protein 337
ZNF518A zinc finger protein 518A
ZXDB zinc finger, X-linked, duplicated B

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ACVR1 activin A receptor, type I
ADGRE2 adhesion G protein-coupled receptor E2
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
AMD1 adenosylmethionine decarboxylase 1
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANXA3 annexin A3
AP4M1 adaptor-related protein complex 4, mu 1 subunit
ARF5 ADP-ribosylation factor 5
ARHGAP12 Rho GTPase activating protein 12
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2
AUH AU RNA binding protein/enoyl-CoA hydratase
BAG2 BCL2-associated athanogene 2
BANP BTG3 associated nuclear protein
C8ORF33 chromosome 8 open reading frame 33
CD38 CD38 molecule
CHML choroideremia-like (Rab escort protein 2)
COL4A2 collagen, type IV, alpha 2
CST3 cystatin C
DBR1 debranching RNA lariats 1
DDB2 damage-specific DNA binding protein 2, 48kDa
DEF8 differentially expressed in FDCP 8 homolog (mouse)
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EML4 echinoderm microtubule associated protein like 4
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
ETV6 ets variant 6
F8 coagulation factor VIII, procoagulant component
FASTKD5 FAST kinase domains 5
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GMCL1 germ cell-less, spermatogenesis associated 1
GMEB1 glucocorticoid modulatory element binding protein 1
GPR27 G protein-coupled receptor 27
GTF2I general transcription factor IIi
GUSBP3 glucuronidase, beta pseudogene 3
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3
HIRA histone cell cycle regulator
HSPA1L heat shock 70kDa protein 1-like
ISG15 ISG15 ubiquitin-like modifier
KAT2B K(lysine) acetyltransferase 2B
KATNBL1 katanin p80 subunit B-like 1
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
KIAA1598
KIF23 kinesin family member 23
KLHL12 kelch-like family member 12
KLHL36 kelch-like family member 36
KPNA4 karyopherin alpha 4 (importin alpha 3)
KPTN kaptin (actin binding protein)
LACTB2 lactamase, beta 2
LIME1 Lck interacting transmembrane adaptor 1
LIN7A lin-7 homolog A (C. elegans)
LMNB1 lamin B1
LRRC42 leucine rich repeat containing 42
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3
MCRS1 microspherule protein 1
MED15 mediator complex subunit 15
MOSPD3 motile sperm domain containing 3
NABP2 nucleic acid binding protein 2
NMB neuromedin B
NNT nicotinamide nucleotide transhydrogenase
NUBPL nucleotide binding protein-like
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
ORC2 origin recognition complex, subunit 2
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
PIGK phosphatidylinositol glycan anchor biosynthesis, class K
PIGT phosphatidylinositol glycan anchor biosynthesis, class T
PIR pirin (iron-binding nuclear protein)
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PMCH pro-melanin-concentrating hormone
POLM polymerase (DNA directed), mu
POLR3F polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator
QTRT1 queuine tRNA-ribosyltransferase 1
RARS arginyl-tRNA synthetase
RBM42 RNA binding motif protein 42
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RIT1 Ras-like without CAAX 1
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
SFT2D2 SFT2 domain containing 2
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3
SND1-IT1 SND1 intronic transcript 1
SNX15 sorting nexin 15
SNX16 sorting nexin 16
SOAT1 sterol O-acyltransferase 1
SPRYD7 SPRY domain containing 7
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TBCCD1 TBCC domain containing 1
TEC tec protein tyrosine kinase
TMEM115 transmembrane protein 115
TOLLIP toll interacting protein
TPBG trophoblast glycoprotein
TSPYL2 TSPY-like 2
TTC26 tetratricopeptide repeat domain 26
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF227 zinc finger protein 227
ZNF83 zinc finger protein 83