napelline-6084 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

198 genes differentially expressed following the napelline-6084 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ACTL8 actin-like 8
AIF1 allograft inflammatory factor 1
AKAP8L A kinase (PRKA) anchor protein 8-like
ALK anaplastic lymphoma receptor tyrosine kinase
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
AVPR1B arginine vasopressin receptor 1B
BIN1 bridging integrator 1
BMP5 bone morphogenetic protein 5
BTN3A1 butyrophilin, subfamily 3, member A1
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CCDC64 coiled-coil domain containing 64
CCDC85B coiled-coil domain containing 85B
CCDC87 coiled-coil domain containing 87
CD1E CD1e molecule
CD79B CD79b molecule, immunoglobulin-associated beta
CDHR2 cadherin-related family member 2
CFAP70 cilia and flagella associated protein 70
CHD5 chromodomain helicase DNA binding protein 5
CIB2 calcium and integrin binding family member 2
CLCN6 chloride channel, voltage-sensitive 6
CPQ carboxypeptidase Q
CRHR2 corticotropin releasing hormone receptor 2
CSF1 colony stimulating factor 1 (macrophage)
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR4 chemokine (C-X-C motif) receptor 4
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DRICH1 aspartate-rich 1
DSC3 desmocollin 3
EGOT eosinophil granule ontogeny transcript (non-protein coding)
EHD1 EH-domain containing 1
EPYC epiphycan
FAM120C family with sequence similarity 120C
FBLN1 fibulin 1
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FRZB frizzled-related protein
FZD10 frizzled class receptor 10
GJA8 gap junction protein, alpha 8, 50kDa
GSN gelsolin
IGHM immunoglobulin heavy constant mu
IL7R interleukin 7 receptor
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains)
KAT6A K(lysine) acetyltransferase 6A
KCNIP2 Kv channel interacting protein 2
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KRT83 keratin 83, type II
LAMB4 laminin, beta 4
LCMT2 leucine carboxyl methyltransferase 2
LRRC23 leucine rich repeat containing 23
LRRC37BP1 leucine rich repeat containing 37B pseudogene 1
MARS methionyl-tRNA synthetase
METTL16 methyltransferase like 16
MFGE8 milk fat globule-EGF factor 8 protein
NPC1 Niemann-Pick disease, type C1
NR6A1 nuclear receptor subfamily 6, group A, member 1
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PECAM1 platelet/endothelial cell adhesion molecule 1
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PML promyelocytic leukemia
PTPRB protein tyrosine phosphatase, receptor type, B
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
REEP2 receptor accessory protein 2
REPS1 RALBP1 associated Eps domain containing 1
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
ROR2 receptor tyrosine kinase-like orphan receptor 2
RPL10 ribosomal protein L10
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
RTN2 reticulon 2
RUNX1 runt-related transcription factor 1
SAMD9 sterile alpha motif domain containing 9
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SFRP4 secreted frizzled-related protein 4
SH3BP2 SH3-domain binding protein 2
SLC35E2 solute carrier family 35, member E2
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SMIM14 small integral membrane protein 14
SPEG SPEG complex locus
SRSF7 serine/arginine-rich splicing factor 7
SSTR2 somatostatin receptor 2
SULT4A1 sulfotransferase family 4A, member 1
TAZ tafazzin
TBX1 T-box 1
TECPR2 tectonin beta-propeller repeat containing 2
TM4SF5 transmembrane 4 L six family member 5
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae)
TRPM3 transient receptor potential cation channel, subfamily M, member 3
U2AF2 U2 small nuclear RNA auxiliary factor 2
VCAN versican
VIPR1 vasoactive intestinal peptide receptor 1
ZER1 zyg-11 related, cell cycle regulator
ZFP2 ZFP2 zinc finger protein
ZFP64 ZFP64 zinc finger protein
ZNF137P zinc finger protein 137, pseudogene
ZNF384 zinc finger protein 384

decreased expression

Symbol Name
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ARMC4 armadillo repeat containing 4
AUTS2 autism susceptibility candidate 2
C11ORF80 chromosome 11 open reading frame 80
C1ORF159 chromosome 1 open reading frame 159
C2ORF54 chromosome 2 open reading frame 54
C5AR2 complement component 5a receptor 2
CCNT1 cyclin T1
CDK3 cyclin-dependent kinase 3
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CDR2L cerebellar degeneration-related protein 2-like
CRIP1 cysteine-rich protein 1 (intestinal)
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DGAT1 diacylglycerol O-acyltransferase 1
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DUSP2 dual specificity phosphatase 2
DUSP9 dual specificity phosphatase 9
ERCC4 excision repair cross-complementation group 4
F2R coagulation factor II (thrombin) receptor
FAM189A2 family with sequence similarity 189, member A2
FAM204A family with sequence similarity 204, member A
FBXW12 F-box and WD repeat domain containing 12
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GINS4 GINS complex subunit 4 (Sld5 homolog)
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GRTP1 growth hormone regulated TBC protein 1
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
GUSBP3 glucuronidase, beta pseudogene 3
HAMP hepcidin antimicrobial peptide
HAUS2 HAUS augmin-like complex, subunit 2
HIST1H1D histone cluster 1, H1d
HIST1H2BJ histone cluster 1, H2bj
HOXA4 homeobox A4
HOXB2 homeobox B2
HOXC10 homeobox C10
HYI hydroxypyruvate isomerase (putative)
IFNA14 interferon, alpha 14
IFT22 intraflagellar transport 22
IL22 interleukin 22
ITGA10 integrin, alpha 10
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KIAA0319L KIAA0319-like
LIN7A lin-7 homolog A (C. elegans)
LMO2 LIM domain only 2 (rhombotin-like 1)
LOC390998 ribosomal protein L10 pseudogene
LOC729164 hCG1732469
LRRC37A3 leucine rich repeat containing 37, member A3
MBTD1 mbt domain containing 1
MFSD11 major facilitator superfamily domain containing 11
MGC12488
NOD1 nucleotide-binding oligomerization domain containing 1
OSGIN1 oxidative stress induced growth inhibitor 1
PARD6B par-6 family cell polarity regulator beta
PCDHA9 protocadherin alpha 9
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PICK1 protein interacting with PRKCA 1
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
PLEKHO2 pleckstrin homology domain containing, family O member 2
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRODH proline dehydrogenase (oxidase) 1
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
RAB40C RAB40C, member RAS oncogene family
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RAPSN receptor-associated protein of the synapse
RPAP1 RNA polymerase II associated protein 1
RPH3AL rabphilin 3A-like (without C2 domains)
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SIGLEC15 sialic acid binding Ig-like lectin 15
SLC16A6 solute carrier family 16, member 6
SLC17A2 solute carrier family 17, member 2
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SPRYD7 SPRY domain containing 7
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma)
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STARD3 StAR-related lipid transfer (START) domain containing 3
TAOK1 TAO kinase 1
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor)
TGFBR1 transforming growth factor, beta receptor 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMCC2 transmembrane and coiled-coil domain family 2
TRIM21 tripartite motif containing 21
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae)
USB1 U6 snRNA biogenesis 1
VEGFB vascular endothelial growth factor B
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZNF286A zinc finger protein 286A
ZNF446 zinc finger protein 446
ZNF480 zinc finger protein 480
ZNF551 zinc finger protein 551
ZNF652 zinc finger protein 652
ZNF675 zinc finger protein 675
ZNF721 zinc finger protein 721