napelline-6824 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the napelline-6824 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADRBK1 adrenergic, beta, receptor kinase 1
AEBP1 AE binding protein 1
AGFG2 ArfGAP with FG repeats 2
AJAP1 adherens junctions associated protein 1
APLP1 amyloid beta (A4) precursor-like protein 1
APOM apolipoprotein M
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ASB1 ankyrin repeat and SOCS box containing 1
ATP11A ATPase, class VI, type 11A
BRD4 bromodomain containing 4
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CASP1 caspase 1, apoptosis-related cysteine peptidase
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CHAT choline O-acetyltransferase
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric)
CNN1 calponin 1, basic, smooth muscle
COL1A1 collagen, type I, alpha 1
CSF1 colony stimulating factor 1 (macrophage)
CTSZ cathepsin Z
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DBT dihydrolipoamide branched chain transacylase E2
DFNB31 deafness, autosomal recessive 31
DSC3 desmocollin 3
E2F5 E2F transcription factor 5, p130-binding
EGF epidermal growth factor
ELAVL3 ELAV like neuron-specific RNA binding protein 3
ELP6 elongator acetyltransferase complex subunit 6
EPHX2 epoxide hydrolase 2, cytoplasmic
ERAP1 endoplasmic reticulum aminopeptidase 1
ESRRA estrogen-related receptor alpha
FBN1 fibrillin 1
FGF6 fibroblast growth factor 6
FLOT1 flotillin 1
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GLIPR1 GLI pathogenesis-related 1
GPER1 G protein-coupled estrogen receptor 1
GRIK5 glutamate receptor, ionotropic, kainate 5
GRM1 glutamate receptor, metabotropic 1
GRPR gastrin-releasing peptide receptor
GYG2 glycogenin 2
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
KCNJ13 potassium channel, inwardly rectifying subfamily J, member 13
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLF13 Kruppel-like factor 13
KRT6B keratin 6B, type II
LDLR low density lipoprotein receptor
LIN7A lin-7 homolog A (C. elegans)
LPCAT4 lysophosphatidylcholine acyltransferase 4
LRRC8B leucine rich repeat containing 8 family, member B
MAN1A2 mannosidase, alpha, class 1A, member 2
MCF2L2 MCF.2 cell line derived transforming sequence-like 2
MOB3B MOB kinase activator 3B
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NRAP nebulin-related anchoring protein
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
OTOR otoraplin
PCNX pecanex homolog (Drosophila)
PDE4DIP phosphodiesterase 4D interacting protein
PDZK1IP1 PDZK1 interacting protein 1
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
POFUT1 protein O-fucosyltransferase 1
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PRDX2 peroxiredoxin 2
PRKCE protein kinase C, epsilon
QSER1 glutamine and serine rich 1
RASL11B RAS-like, family 11, member B
RB1 retinoblastoma 1
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RIF1 replication timing regulatory factor 1
RNF208 ring finger protein 208
RPLP2 ribosomal protein, large, P2
SCAPER S-phase cyclin A-associated protein in the ER
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SERHL2 serine hydrolase-like 2
SIGLEC8 sialic acid binding Ig-like lectin 8
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SPTB spectrin, beta, erythrocytic
SRPK2 SRSF protein kinase 2
SYT11 synaptotagmin XI
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TP73-AS1 TP73 antisense RNA 1
TUBA4B tubulin, alpha 4b
WDTC1 WD and tetratricopeptide repeats 1
WNT16 wingless-type MMTV integration site family, member 16
WNT6 wingless-type MMTV integration site family, member 6
ZBTB18 zinc finger and BTB domain containing 18
ZNF484 zinc finger protein 484
ZNF518A zinc finger protein 518A
ZNF682 zinc finger protein 682
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ACAD10 acyl-CoA dehydrogenase family, member 10
ARRB1 arrestin, beta 1
BPGM 2,3-bisphosphoglycerate mutase
C16ORF45 chromosome 16 open reading frame 45
CAMK1D calcium/calmodulin-dependent protein kinase ID
CARD8 caspase recruitment domain family, member 8
CCDC121 coiled-coil domain containing 121
CCDC85C coiled-coil domain containing 85C
CDK3 cyclin-dependent kinase 3
CDKL3 cyclin-dependent kinase-like 3
CEP72 centrosomal protein 72kDa
CIC capicua transcriptional repressor
CLDND1 claudin domain containing 1
CRIP1 cysteine-rich protein 1 (intestinal)
CUL9 cullin 9
CXADR coxsackie virus and adenovirus receptor
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DSCAM Down syndrome cell adhesion molecule
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EGFL7 EGF-like-domain, multiple 7
EIF5A2 eukaryotic translation initiation factor 5A2
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
FAM169A family with sequence similarity 169, member A
FAM46C family with sequence similarity 46, member C
FBXL4 F-box and leucine-rich repeat protein 4
FLRT3 fibronectin leucine rich transmembrane protein 3
FOXJ2 forkhead box J2
GAMT guanidinoacetate N-methyltransferase
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GSTTP1 glutathione S-transferase theta pseudogene 1
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HIST1H4D histone cluster 1, H4d
HPSE heparanase
IFI27 interferon, alpha-inducible protein 27
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFT54 intraflagellar transport 54
IGSF1 immunoglobulin superfamily, member 1
IL4R interleukin 4 receptor
IRAK4 interleukin-1 receptor-associated kinase 4
LIG4 ligase IV, DNA, ATP-dependent
LOC729164 hCG1732469
LRRC20 leucine rich repeat containing 20
LYRM9 LYR motif containing 9
LZTR1 leucine-zipper-like transcription regulator 1
MFAP2 microfibrillar-associated protein 2
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NECAB3 N-terminal EF-hand calcium binding protein 3
NRGN neurogranin (protein kinase C substrate, RC3)
NRSN2 neurensin 2
NT5DC3 5'-nucleotidase domain containing 3
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PADI2 peptidyl arginine deiminase, type II
PADI3 peptidyl arginine deiminase, type III
PARG poly (ADP-ribose) glycohydrolase
PCBP4 poly(rC) binding protein 4
PGM1 phosphoglucomutase 1
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
PSG4 pregnancy specific beta-1-glycoprotein 4
PTPN14 protein tyrosine phosphatase, non-receptor type 14
RAB3A RAB3A, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAD54L2 RAD54-like 2 (S. cerevisiae)
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RFXAP regulatory factor X-associated protein
RIN1 Ras and Rab interactor 1
RNF2 ring finger protein 2
RPGR retinitis pigmentosa GTPase regulator
RPL23AP7 ribosomal protein L23a pseudogene 7
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
SAYSD1 SAYSVFN motif domain containing 1
SDC3 syndecan 3
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SIGLEC15 sialic acid binding Ig-like lectin 15
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STX1A syntaxin 1A (brain)
TAOK1 TAO kinase 1
TCTN2 tectonic family member 2
TESK2 testis-specific kinase 2
TICAM1 toll-like receptor adaptor molecule 1
TLR2 toll-like receptor 2
TM6SF1 transmembrane 6 superfamily member 1
TMEM254 transmembrane protein 254
TOM1 target of myb1 (chicken)
TRAPPC11 trafficking protein particle complex 11
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TTC9 tetratricopeptide repeat domain 9
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
USB1 U6 snRNA biogenesis 1
ZBTB48 zinc finger and BTB domain containing 48
ZNF34 zinc finger protein 34
ZNF37BP zinc finger protein 37B, pseudogene
ZNF606 zinc finger protein 606