| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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198 genes differentially expressed following the napelline-6824 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADRBK1 | adrenergic, beta, receptor kinase 1 |
| AEBP1 | AE binding protein 1 |
| AGFG2 | ArfGAP with FG repeats 2 |
| AJAP1 | adherens junctions associated protein 1 |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| APOM | apolipoprotein M |
| ARAP1 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 |
| ASB1 | ankyrin repeat and SOCS box containing 1 |
| ATP11A | ATPase, class VI, type 11A |
| BRD4 | bromodomain containing 4 |
| CACNG1 | calcium channel, voltage-dependent, gamma subunit 1 |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta |
| CHAT | choline O-acetyltransferase |
| CKMT2 | creatine kinase, mitochondrial 2 (sarcomeric) |
| CNN1 | calponin 1, basic, smooth muscle |
| COL1A1 | collagen, type I, alpha 1 |
| CSF1 | colony stimulating factor 1 (macrophage) |
| CTSZ | cathepsin Z |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| DBT | dihydrolipoamide branched chain transacylase E2 |
| DFNB31 | deafness, autosomal recessive 31 |
| DSC3 | desmocollin 3 |
| E2F5 | E2F transcription factor 5, p130-binding |
| EGF | epidermal growth factor |
| ELAVL3 | ELAV like neuron-specific RNA binding protein 3 |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| EPHX2 | epoxide hydrolase 2, cytoplasmic |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 |
| ESRRA | estrogen-related receptor alpha |
| FBN1 | fibrillin 1 |
| FGF6 | fibroblast growth factor 6 |
| FLOT1 | flotillin 1 |
| GAD1 | glutamate decarboxylase 1 (brain, 67kDa) |
| GLIPR1 | GLI pathogenesis-related 1 |
| GPER1 | G protein-coupled estrogen receptor 1 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| GRM1 | glutamate receptor, metabotropic 1 |
| GRPR | gastrin-releasing peptide receptor |
| GYG2 | glycogenin 2 |
| HTR4 | 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled |
| IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) |
| KCNA3 | potassium channel, voltage gated shaker related subfamily A, member 3 |
| KCNJ13 | potassium channel, inwardly rectifying subfamily J, member 13 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 |
| KCNN2 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 |
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog |
| KLF13 | Kruppel-like factor 13 |
| KRT6B | keratin 6B, type II |
| LDLR | low density lipoprotein receptor |
| LIN7A | lin-7 homolog A (C. elegans) |
| LPCAT4 | lysophosphatidylcholine acyltransferase 4 |
| LRRC8B | leucine rich repeat containing 8 family, member B |
| MAN1A2 | mannosidase, alpha, class 1A, member 2 |
| MCF2L2 | MCF.2 cell line derived transforming sequence-like 2 |
| MOB3B | MOB kinase activator 3B |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NRAP | nebulin-related anchoring protein |
| NTRK3 | neurotrophic tyrosine kinase, receptor, type 3 |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| OTOR | otoraplin |
| PCNX | pecanex homolog (Drosophila) |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PDZK1IP1 | PDZK1 interacting protein 1 |
| PHLPP2 | PH domain and leucine rich repeat protein phosphatase 2 |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| POFUT1 | protein O-fucosyltransferase 1 |
| PPFIBP2 | PTPRF interacting protein, binding protein 2 (liprin beta 2) |
| PRDX2 | peroxiredoxin 2 |
| PRKCE | protein kinase C, epsilon |
| QSER1 | glutamine and serine rich 1 |
| RASL11B | RAS-like, family 11, member B |
| RB1 | retinoblastoma 1 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
| RIF1 | replication timing regulatory factor 1 |
| RNF208 | ring finger protein 208 |
| RPLP2 | ribosomal protein, large, P2 |
| SCAPER | S-phase cyclin A-associated protein in the ER |
| SDHB | succinate dehydrogenase complex, subunit B, iron sulfur (Ip) |
| SERHL2 | serine hydrolase-like 2 |
| SIGLEC8 | sialic acid binding Ig-like lectin 8 |
| SLC43A1 | solute carrier family 43 (amino acid system L transporter), member 1 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SPTB | spectrin, beta, erythrocytic |
| SRPK2 | SRSF protein kinase 2 |
| SYT11 | synaptotagmin XI |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TP73-AS1 | TP73 antisense RNA 1 |
| TUBA4B | tubulin, alpha 4b |
| WDTC1 | WD and tetratricopeptide repeats 1 |
| WNT16 | wingless-type MMTV integration site family, member 16 |
| WNT6 | wingless-type MMTV integration site family, member 6 |
| ZBTB18 | zinc finger and BTB domain containing 18 |
| ZNF484 | zinc finger protein 484 |
| ZNF518A | zinc finger protein 518A |
| ZNF682 | zinc finger protein 682 |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 |
| Symbol | Name |
|---|---|
| ACAD10 | acyl-CoA dehydrogenase family, member 10 |
| ARRB1 | arrestin, beta 1 |
| BPGM | 2,3-bisphosphoglycerate mutase |
| C16ORF45 | chromosome 16 open reading frame 45 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID |
| CARD8 | caspase recruitment domain family, member 8 |
| CCDC121 | coiled-coil domain containing 121 |
| CCDC85C | coiled-coil domain containing 85C |
| CDK3 | cyclin-dependent kinase 3 |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CEP72 | centrosomal protein 72kDa |
| CIC | capicua transcriptional repressor |
| CLDND1 | claudin domain containing 1 |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CUL9 | cullin 9 |
| CXADR | coxsackie virus and adenovirus receptor |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DSCAM | Down syndrome cell adhesion molecule |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| EGFL7 | EGF-like-domain, multiple 7 |
| EIF5A2 | eukaryotic translation initiation factor 5A2 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| FAM169A | family with sequence similarity 169, member A |
| FAM46C | family with sequence similarity 46, member C |
| FBXL4 | F-box and leucine-rich repeat protein 4 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 |
| FOXJ2 | forkhead box J2 |
| GAMT | guanidinoacetate N-methyltransferase |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GSTTP1 | glutathione S-transferase theta pseudogene 1 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HIST1H4D | histone cluster 1, H4d |
| HPSE | heparanase |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFT54 | intraflagellar transport 54 |
| IGSF1 | immunoglobulin superfamily, member 1 |
| IL4R | interleukin 4 receptor |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LOC729164 | hCG1732469 |
| LRRC20 | leucine rich repeat containing 20 |
| LYRM9 | LYR motif containing 9 |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MFAP2 | microfibrillar-associated protein 2 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| NECAB3 | N-terminal EF-hand calcium binding protein 3 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| NRSN2 | neurensin 2 |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| PADI2 | peptidyl arginine deiminase, type II |
| PADI3 | peptidyl arginine deiminase, type III |
| PARG | poly (ADP-ribose) glycohydrolase |
| PCBP4 | poly(rC) binding protein 4 |
| PGM1 | phosphoglucomutase 1 |
| PLEKHG6 | pleckstrin homology domain containing, family G (with RhoGef domain) member 6 |
| PSG4 | pregnancy specific beta-1-glycoprotein 4 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 |
| RAB3A | RAB3A, member RAS oncogene family |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| RFXAP | regulatory factor X-associated protein |
| RIN1 | Ras and Rab interactor 1 |
| RNF2 | ring finger protein 2 |
| RPGR | retinitis pigmentosa GTPase regulator |
| RPL23AP7 | ribosomal protein L23a pseudogene 7 |
| RPRM | reprimo, TP53 dependent G2 arrest mediator candidate |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SDC3 | syndecan 3 |
| SGTA | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 |
| SLC9A5 | solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STX1A | syntaxin 1A (brain) |
| TAOK1 | TAO kinase 1 |
| TCTN2 | tectonic family member 2 |
| TESK2 | testis-specific kinase 2 |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TLR2 | toll-like receptor 2 |
| TM6SF1 | transmembrane 6 superfamily member 1 |
| TMEM254 | transmembrane protein 254 |
| TOM1 | target of myb1 (chicken) |
| TRAPPC11 | trafficking protein particle complex 11 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TTC9 | tetratricopeptide repeat domain 9 |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| USB1 | U6 snRNA biogenesis 1 |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZNF34 | zinc finger protein 34 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF606 | zinc finger protein 606 |