naphazoline-1966 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the naphazoline-1966 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADRBK1 adrenergic, beta, receptor kinase 1
ANKRD12 ankyrin repeat domain 12
AQP9 aquaporin 9
ARHGAP4 Rho GTPase activating protein 4
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2
AXIN1 axin 1
BATF basic leucine zipper transcription factor, ATF-like
BMP7 bone morphogenetic protein 7
C5ORF30 chromosome 5 open reading frame 30
C5ORF45 chromosome 5 open reading frame 45
CDK10 cyclin-dependent kinase 10
CDK9 cyclin-dependent kinase 9
CEP63 centrosomal protein 63kDa
CHAF1B chromatin assembly factor 1, subunit B (p60)
CKB creatine kinase, brain
CLEC11A C-type lectin domain family 11, member A
CS citrate synthase
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYLD cylindromatosis (turban tumor syndrome)
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1
DUSP2 dual specificity phosphatase 2
DYNC2LI1 dynein, cytoplasmic 2, light intermediate chain 1
E2F1 E2F transcription factor 1
EHD1 EH-domain containing 1
FANCF Fanconi anemia, complementation group F
FURIN furin (paired basic amino acid cleaving enzyme)
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
GIMAP5 GTPase, IMAP family member 5
GPSM2 G-protein signaling modulator 2
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa
HIST3H2A histone cluster 3, H2a
HMMR hyaluronan-mediated motility receptor (RHAMM)
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HPS1 Hermansky-Pudlak syndrome 1
ICAM1 intercellular adhesion molecule 1
IGKV1D-13 immunoglobulin kappa variable 1D-13
INPP1 inositol polyphosphate-1-phosphatase
ITSN1 intersectin 1 (SH3 domain protein)
L2HGDH L-2-hydroxyglutarate dehydrogenase
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
MAN1B1 mannosidase, alpha, class 1B, member 1
MNS1 meiosis-specific nuclear structural 1
NBEAL2 neurobeachin-like 2
NBR1 neighbor of BRCA1 gene 1
NCOA3 nuclear receptor coactivator 3
NRBP1 nuclear receptor binding protein 1
OR10J1 olfactory receptor, family 10, subfamily J, member 1
PARP16 poly (ADP-ribose) polymerase family, member 16
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PCSK7 proprotein convertase subtilisin/kexin type 7
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PELI1 pellino E3 ubiquitin protein ligase 1
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
PKD1 polycystic kidney disease 1 (autosomal dominant)
PLEC plectin
PLEK2 pleckstrin 2
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PSG3 pregnancy specific beta-1-glycoprotein 3
RAD17 RAD17 homolog (S. pombe)
RAD54B RAD54 homolog B (S. cerevisiae)
RAD54L2 RAD54-like 2 (S. cerevisiae)
RBM10 RNA binding motif protein 10
RBM34 RNA binding motif protein 34
RHOT2 ras homolog family member T2
RNASE3 ribonuclease, RNase A family, 3
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
S100A6 S100 calcium binding protein A6
SEC31B SEC31 homolog B (S. cerevisiae)
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SH2D1A SH2 domain containing 1A
SKAP2 src kinase associated phosphoprotein 2
SLC22A7 solute carrier family 22 (organic anion transporter), member 7
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SMAD6 SMAD family member 6
SP100 SP100 nuclear antigen
SPTLC1 serine palmitoyltransferase, long chain base subunit 1
STAP2 signal transducing adaptor family member 2
STK19 serine/threonine kinase 19
SUGP1 SURP and G patch domain containing 1
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
TFE3 transcription factor binding to IGHM enhancer 3
TMEM206 transmembrane protein 206
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TOLLIP toll interacting protein
TYR tyrosinase
WAS Wiskott-Aldrich syndrome
WDR13 WD repeat domain 13
ZKSCAN5 zinc finger with KRAB and SCAN domains 5
ZNF35 zinc finger protein 35
ZNF44 zinc finger protein 44
ZNF804A zinc finger protein 804A

decreased expression

Symbol Name
ABHD3 abhydrolase domain containing 3
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain
ADRB2 adrenoceptor beta 2, surface
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5
AHR aryl hydrocarbon receptor
ARID3A AT rich interactive domain 3A (BRIGHT-like)
BBC3 BCL2 binding component 3
BCORL1 BCL6 corepressor-like 1
C16ORF62 chromosome 16 open reading frame 62
C5ORF28 chromosome 5 open reading frame 28
CCDC51 coiled-coil domain containing 51
CCNA1 cyclin A1
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CLDN15 claudin 15
CLEC16A C-type lectin domain family 16, member A
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2
CTR9 CTR9, Paf1/RNA polymerase II complex component
DHDDS dehydrodolichyl diphosphate synthase
FAM114A2 family with sequence similarity 114, member A2
FCHSD2 FCH and double SH3 domains 2
FGF4 fibroblast growth factor 4
FPGS folylpolyglutamate synthase
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GDI1 GDP dissociation inhibitor 1
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GJD2 gap junction protein, delta 2, 36kDa
GMCL1 germ cell-less, spermatogenesis associated 1
GPN3 GPN-loop GTPase 3
GSR glutathione reductase
GUSBP3 glucuronidase, beta pseudogene 3
HDAC9 histone deacetylase 9
HEATR3 HEAT repeat containing 3
HIRA histone cell cycle regulator
HIST1H1E histone cluster 1, H1e
INO80D INO80 complex subunit D
KIAA0894 KIAA0894 protein
KRI1 KRI1 homolog (S. cerevisiae)
LGALS9 lectin, galactoside-binding, soluble, 9
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
MED23 mediator complex subunit 23
MEPCE methylphosphate capping enzyme
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
MYO5C myosin VC
MYO9A myosin IXA
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit
NIP7 NIP7, nucleolar pre-rRNA processing protein
NOL12 nucleolar protein 12
NTHL1 nth endonuclease III-like 1 (E. coli)
OGFRL1 opioid growth factor receptor-like 1
PARG poly (ADP-ribose) glycohydrolase
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PMM2 phosphomannomutase 2
PNPO pyridoxamine 5'-phosphate oxidase
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
POU2F1 POU class 2 homeobox 1
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D
RAPGEF6 Rap guanine nucleotide exchange factor (GEF) 6
RECQL4 RecQ protein-like 4
RNF122 ring finger protein 122
RPAP1 RNA polymerase II associated protein 1
RPP38 ribonuclease P/MRP 38kDa subunit
RPUSD2 RNA pseudouridylate synthase domain containing 2
RRP1 ribosomal RNA processing 1
SCML2 sex comb on midleg-like 2 (Drosophila)
SECISBP2 SECIS binding protein 2
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SH3GL1 SH3-domain GRB2-like 1
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SLMO2 slowmo homolog 2 (Drosophila)
SLPI secretory leukocyte peptidase inhibitor
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
SNX15 sorting nexin 15
SP3 Sp3 transcription factor
SREBF1 sterol regulatory element binding transcription factor 1
STAC SH3 and cysteine rich domain
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae)
TAC3 tachykinin 3
TBCCD1 TBCC domain containing 1
TCTN2 tectonic family member 2
TFB2M transcription factor B2, mitochondrial
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMBIM4 transmembrane BAX inhibitor motif containing 4
TMEM184C transmembrane protein 184C
TOB1 transducer of ERBB2, 1
TUBA3C tubulin, alpha 3c
UBE2O ubiquitin-conjugating enzyme E2O
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae)
ZDHHC7 zinc finger, DHHC-type containing 7
ZNF721 zinc finger protein 721