| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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198 genes differentially expressed following the naphazoline-1966 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADRBK1 | adrenergic, beta, receptor kinase 1 |
| ANKRD12 | ankyrin repeat domain 12 |
| AQP9 | aquaporin 9 |
| ARHGAP4 | Rho GTPase activating protein 4 |
| ARIH2 | ariadne RBR E3 ubiquitin protein ligase 2 |
| AXIN1 | axin 1 |
| BATF | basic leucine zipper transcription factor, ATF-like |
| BMP7 | bone morphogenetic protein 7 |
| C5ORF30 | chromosome 5 open reading frame 30 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CDK10 | cyclin-dependent kinase 10 |
| CDK9 | cyclin-dependent kinase 9 |
| CEP63 | centrosomal protein 63kDa |
| CHAF1B | chromatin assembly factor 1, subunit B (p60) |
| CKB | creatine kinase, brain |
| CLEC11A | C-type lectin domain family 11, member A |
| CS | citrate synthase |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| CYLD | cylindromatosis (turban tumor syndrome) |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 |
| DUSP2 | dual specificity phosphatase 2 |
| DYNC2LI1 | dynein, cytoplasmic 2, light intermediate chain 1 |
| E2F1 | E2F transcription factor 1 |
| EHD1 | EH-domain containing 1 |
| FANCF | Fanconi anemia, complementation group F |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) |
| GIMAP5 | GTPase, IMAP family member 5 |
| GPSM2 | G-protein signaling modulator 2 |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
| GTF3C1 | general transcription factor IIIC, polypeptide 1, alpha 220kDa |
| HIST3H2A | histone cluster 3, H2a |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) |
| HPS1 | Hermansky-Pudlak syndrome 1 |
| ICAM1 | intercellular adhesion molecule 1 |
| IGKV1D-13 | immunoglobulin kappa variable 1D-13 |
| INPP1 | inositol polyphosphate-1-phosphatase |
| ITSN1 | intersectin 1 (SH3 domain protein) |
| L2HGDH | L-2-hydroxyglutarate dehydrogenase |
| LILRB1 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| MAN1B1 | mannosidase, alpha, class 1B, member 1 |
| MNS1 | meiosis-specific nuclear structural 1 |
| NBEAL2 | neurobeachin-like 2 |
| NBR1 | neighbor of BRCA1 gene 1 |
| NCOA3 | nuclear receptor coactivator 3 |
| NRBP1 | nuclear receptor binding protein 1 |
| OR10J1 | olfactory receptor, family 10, subfamily J, member 1 |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PATZ1 | POZ (BTB) and AT hook containing zinc finger 1 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) |
| PELI1 | pellino E3 ubiquitin protein ligase 1 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase, type II, beta |
| PKD1 | polycystic kidney disease 1 (autosomal dominant) |
| PLEC | plectin |
| PLEK2 | pleckstrin 2 |
| POLD4 | polymerase (DNA-directed), delta 4, accessory subunit |
| PPM1A | protein phosphatase, Mg2+/Mn2+ dependent, 1A |
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta |
| PRKAA1 | protein kinase, AMP-activated, alpha 1 catalytic subunit |
| PSG3 | pregnancy specific beta-1-glycoprotein 3 |
| RAD17 | RAD17 homolog (S. pombe) |
| RAD54B | RAD54 homolog B (S. cerevisiae) |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RBM10 | RNA binding motif protein 10 |
| RBM34 | RNA binding motif protein 34 |
| RHOT2 | ras homolog family member T2 |
| RNASE3 | ribonuclease, RNase A family, 3 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 |
| S100A6 | S100 calcium binding protein A6 |
| SEC31B | SEC31 homolog B (S. cerevisiae) |
| SEMA4F | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) |
| SH2D1A | SH2 domain containing 1A |
| SKAP2 | src kinase associated phosphoprotein 2 |
| SLC22A7 | solute carrier family 22 (organic anion transporter), member 7 |
| SLC29A3 | solute carrier family 29 (equilibrative nucleoside transporter), member 3 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SMAD6 | SMAD family member 6 |
| SP100 | SP100 nuclear antigen |
| SPTLC1 | serine palmitoyltransferase, long chain base subunit 1 |
| STAP2 | signal transducing adaptor family member 2 |
| STK19 | serine/threonine kinase 19 |
| SUGP1 | SURP and G patch domain containing 1 |
| TAF12 | TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa |
| TFE3 | transcription factor binding to IGHM enhancer 3 |
| TMEM206 | transmembrane protein 206 |
| TNFAIP1 | tumor necrosis factor, alpha-induced protein 1 (endothelial) |
| TOLLIP | toll interacting protein |
| TYR | tyrosinase |
| WAS | Wiskott-Aldrich syndrome |
| WDR13 | WD repeat domain 13 |
| ZKSCAN5 | zinc finger with KRAB and SCAN domains 5 |
| ZNF35 | zinc finger protein 35 |
| ZNF44 | zinc finger protein 44 |
| ZNF804A | zinc finger protein 804A |
| Symbol | Name |
|---|---|
| ABHD3 | abhydrolase domain containing 3 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase |
| ACADM | acyl-CoA dehydrogenase, C-4 to C-12 straight chain |
| ADRB2 | adrenoceptor beta 2, surface |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 |
| AHR | aryl hydrocarbon receptor |
| ARID3A | AT rich interactive domain 3A (BRIGHT-like) |
| BBC3 | BCL2 binding component 3 |
| BCORL1 | BCL6 corepressor-like 1 |
| C16ORF62 | chromosome 16 open reading frame 62 |
| C5ORF28 | chromosome 5 open reading frame 28 |
| CCDC51 | coiled-coil domain containing 51 |
| CCNA1 | cyclin A1 |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| CHST5 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 |
| CLDN15 | claudin 15 |
| CLEC16A | C-type lectin domain family 16, member A |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 |
| CTR9 | CTR9, Paf1/RNA polymerase II complex component |
| DHDDS | dehydrodolichyl diphosphate synthase |
| FAM114A2 | family with sequence similarity 114, member A2 |
| FCHSD2 | FCH and double SH3 domains 2 |
| FGF4 | fibroblast growth factor 4 |
| FPGS | folylpolyglutamate synthase |
| GATB | glutamyl-tRNA(Gln) amidotransferase, subunit B |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C |
| GDI1 | GDP dissociation inhibitor 1 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GJD2 | gap junction protein, delta 2, 36kDa |
| GMCL1 | germ cell-less, spermatogenesis associated 1 |
| GPN3 | GPN-loop GTPase 3 |
| GSR | glutathione reductase |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HDAC9 | histone deacetylase 9 |
| HEATR3 | HEAT repeat containing 3 |
| HIRA | histone cell cycle regulator |
| HIST1H1E | histone cluster 1, H1e |
| INO80D | INO80 complex subunit D |
| KIAA0894 | KIAA0894 protein |
| KRI1 | KRI1 homolog (S. cerevisiae) |
| LGALS9 | lectin, galactoside-binding, soluble, 9 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 |
| MED23 | mediator complex subunit 23 |
| MEPCE | methylphosphate capping enzyme |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase |
| MYO5C | myosin VC |
| MYO9A | myosin IXA |
| NAA50 | N(alpha)-acetyltransferase 50, NatE catalytic subunit |
| NIP7 | NIP7, nucleolar pre-rRNA processing protein |
| NOL12 | nucleolar protein 12 |
| NTHL1 | nth endonuclease III-like 1 (E. coli) |
| OGFRL1 | opioid growth factor receptor-like 1 |
| PARG | poly (ADP-ribose) glycohydrolase |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PIN1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 |
| PMM2 | phosphomannomutase 2 |
| PNPO | pyridoxamine 5'-phosphate oxidase |
| POP1 | processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) |
| POU2F1 | POU class 2 homeobox 1 |
| PPP1R14D | protein phosphatase 1, regulatory (inhibitor) subunit 14D |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 |
| RECQL4 | RecQ protein-like 4 |
| RNF122 | ring finger protein 122 |
| RPAP1 | RNA polymerase II associated protein 1 |
| RPP38 | ribonuclease P/MRP 38kDa subunit |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| RRP1 | ribosomal RNA processing 1 |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SECISBP2 | SECIS binding protein 2 |
| SELP | selectin P (granule membrane protein 140kDa, antigen CD62) |
| SH3GL1 | SH3-domain GRB2-like 1 |
| SLC19A2 | solute carrier family 19 (thiamine transporter), member 2 |
| SLC25A15 | solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 |
| SLC29A2 | solute carrier family 29 (equilibrative nucleoside transporter), member 2 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 |
| SLMO2 | slowmo homolog 2 (Drosophila) |
| SLPI | secretory leukocyte peptidase inhibitor |
| SMARCAL1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 |
| SNX15 | sorting nexin 15 |
| SP3 | Sp3 transcription factor |
| SREBF1 | sterol regulatory element binding transcription factor 1 |
| STAC | SH3 and cysteine rich domain |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) |
| TAC3 | tachykinin 3 |
| TBCCD1 | TBCC domain containing 1 |
| TCTN2 | tectonic family member 2 |
| TFB2M | transcription factor B2, mitochondrial |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TMBIM4 | transmembrane BAX inhibitor motif containing 4 |
| TMEM184C | transmembrane protein 184C |
| TOB1 | transducer of ERBB2, 1 |
| TUBA3C | tubulin, alpha 3c |
| UBE2O | ubiquitin-conjugating enzyme E2O |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 |
| VPS8 | vacuolar protein sorting 8 homolog (S. cerevisiae) |
| ZDHHC7 | zinc finger, DHHC-type containing 7 |
| ZNF721 | zinc finger protein 721 |