naphazoline-4949 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the naphazoline-4949 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ADAM22 ADAM metallopeptidase domain 22
ADARB1 adenosine deaminase, RNA-specific, B1
AGFG1 ArfGAP with FG repeats 1
AGRP agouti related neuropeptide
AHI1 Abelson helper integration site 1
AJAP1 adherens junctions associated protein 1
AMPD1 adenosine monophosphate deaminase 1
ANAPC13 anaphase promoting complex subunit 13
ANGPT4 angiopoietin 4
APOLD1 apolipoprotein L domain containing 1
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
B9D1 B9 protein domain 1
BIRC7 baculoviral IAP repeat containing 7
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
CACYBP calcyclin binding protein
CEP112 centrosomal protein 112kDa
CEP41 centrosomal protein 41kDa
CFHR4 complement factor H-related 4
CHML choroideremia-like (Rab escort protein 2)
CLCN7 chloride channel, voltage-sensitive 7
COL6A1 collagen, type VI, alpha 1
DGCR8 DGCR8 microprocessor complex subunit
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
ELOVL2 ELOVL fatty acid elongase 2
EMCN endomucin
ETV5 ets variant 5
FAM131A family with sequence similarity 131, member A
FAM46C family with sequence similarity 46, member C
FGF13 fibroblast growth factor 13
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GAMT guanidinoacetate N-methyltransferase
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GRPR gastrin-releasing peptide receptor
HCRP1 hepatocellular carcinoma-related HCRP1
HIP1 huntingtin interacting protein 1
HIST1H4F histone cluster 1, H4f
IFT27 intraflagellar transport 27
INSR insulin receptor
KIAA0319L KIAA0319-like
LRP6 low density lipoprotein receptor-related protein 6
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAGEA5 melanoma antigen family A5
MAST3 microtubule associated serine/threonine kinase 3
MCFD2 multiple coagulation factor deficiency 2
MIA3 melanoma inhibitory activity family, member 3
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MST1 macrophage stimulating 1
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NME5 NME/NM23 family member 5
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR6A1 nuclear receptor subfamily 6, group A, member 1
NUP188 nucleoporin 188kDa
OLFML2A olfactomedin-like 2A
OSGIN2 oxidative stress induced growth inhibitor family member 2
PACS1 phosphofurin acidic cluster sorting protein 1
PARD3 par-3 family cell polarity regulator
PCDH17 protocadherin 17
PCDH7 protocadherin 7
PCNX pecanex homolog (Drosophila)
PCSK6 proprotein convertase subtilisin/kexin type 6
PDGFA platelet-derived growth factor alpha polypeptide
PEX16 peroxisomal biogenesis factor 16
PEX3 peroxisomal biogenesis factor 3
PLAU plasminogen activator, urokinase
PLK3 polo-like kinase 3
PTHLH parathyroid hormone-like hormone
PTK2B protein tyrosine kinase 2 beta
RIMS2 regulating synaptic membrane exocytosis 2
RND1 Rho family GTPase 1
RPL35A ribosomal protein L35a
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SIDT2 SID1 transmembrane family, member 2
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMAD3 SMAD family member 3
STIM1 stromal interaction molecule 1
STRA6 stimulated by retinoic acid 6
SUGP1 SURP and G patch domain containing 1
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
TADA2A transcriptional adaptor 2A
TBX3 T-box 3
THAP3 THAP domain containing, apoptosis associated protein 3
TLR5 toll-like receptor 5
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1
TMOD1 tropomodulin 1
TRIM36 tripartite motif containing 36
TTC9 tetratricopeptide repeat domain 9
UBQLN4 ubiquilin 4
UHRF1BP1L UHRF1 binding protein 1-like
UMPS uridine monophosphate synthetase
VDAC3 voltage-dependent anion channel 3
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
YTHDC2 YTH domain containing 2
ZBTB14 zinc finger and BTB domain containing 14
ZFP36L1 ZFP36 ring finger protein-like 1
ZNF493 zinc finger protein 493

decreased expression

Symbol Name
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ALPK1 alpha-kinase 1
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BAHCC1 BAH domain and coiled-coil containing 1
BATF basic leucine zipper transcription factor, ATF-like
C2ORF54 chromosome 2 open reading frame 54
CA5BP1 carbonic anhydrase VB pseudogene 1
CASZ1 castor zinc finger 1
CCDC132 coiled-coil domain containing 132
CD83 CD83 molecule
CGA glycoprotein hormones, alpha polypeptide
CHMP7 charged multivesicular body protein 7
CHST10 carbohydrate sulfotransferase 10
CIDEB cell death-inducing DFFA-like effector b
CORT cortistatin
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DEAF1 DEAF1 transcription factor
DGKD diacylglycerol kinase, delta 130kDa
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
EFHD2 EF-hand domain family, member D2
ELMO3 engulfment and cell motility 3
ENGASE endo-beta-N-acetylglucosaminidase
FAM160B2 family with sequence similarity 160, member B2
FKBP10 FK506 binding protein 10, 65 kDa
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GMPPA GDP-mannose pyrophosphorylase A
HIST1H1D histone cluster 1, H1d
HIST1H2AI histone cluster 1, H2ai
HOXC10 homeobox C10
IFI27 interferon, alpha-inducible protein 27
IFT140 intraflagellar transport 140
ITPKB inositol-trisphosphate 3-kinase B
ITPKC inositol-trisphosphate 3-kinase C
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KIAA0754 KIAA0754
KLF3 Kruppel-like factor 3 (basic)
KRT8P12 keratin 8 pseudogene 12
LAMB3 laminin, beta 3
LOC729164 hCG1732469
LPPR1 lipid phosphate phosphatase-related protein type 1
MED15 mediator complex subunit 15
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MSI1 musashi RNA-binding protein 1
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
MVP major vault protein
MYF5 myogenic factor 5
NPFFR1 neuropeptide FF receptor 1
NRGN neurogranin (protein kinase C substrate, RC3)
NXPH4 neurexophilin 4
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
PADI1 peptidyl arginine deiminase, type I
PCDHA6 protocadherin alpha 6
PDK1 pyruvate dehydrogenase kinase, isozyme 1
POLL polymerase (DNA directed), lambda
POM121 POM121 transmembrane nucleoporin
PPP1R13L protein phosphatase 1, regulatory subunit 13 like
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRPH peripherin
PTPRU protein tyrosine phosphatase, receptor type, U
QPCT glutaminyl-peptide cyclotransferase
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RBM38 RNA binding motif protein 38
RCAN3 RCAN family member 3
RLN1 relaxin 1
RPGRIP1L RPGRIP1-like
SCGB2A2 secretoglobin, family 2A, member 2
SCPEP1 serine carboxypeptidase 1
SIX1 SIX homeobox 1
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SOWAHC sosondowah ankyrin repeat domain family member C
STEAP1 six transmembrane epithelial antigen of the prostate 1
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TAOK1 TAO kinase 1
TCHH trichohyalin
TET3 tet methylcytosine dioxygenase 3
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TH tyrosine hydroxylase
TMEM212 transmembrane protein 212
TPCN1 two pore segment channel 1
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TSGA10 testis specific, 10
TUBA3C tubulin, alpha 3c
TWF2 twinfilin actin binding protein 2
UCN urocortin
VASH1 vasohibin 1
WDR25 WD repeat domain 25
WDR62 WD repeat domain 62
ZNF205 zinc finger protein 205
ZNF74 zinc finger protein 74
ZNF767P zinc finger family member 767, pseudogene
ZSWIM1 zinc finger, SWIM-type containing 1