naphazoline-6604 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the naphazoline-6604 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ACOXL acyl-CoA oxidase-like
ADAM3A ADAM metallopeptidase domain 3A (pseudogene)
AHSP alpha hemoglobin stabilizing protein
AIPL1 aryl hydrocarbon receptor interacting protein-like 1
ALDOB aldolase B, fructose-bisphosphate
AMPH amphiphysin
APOH apolipoprotein H (beta-2-glycoprotein I)
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
C14ORF1 chromosome 14 open reading frame 1
CALHM2 calcium homeostasis modulator 2
CCDC121 coiled-coil domain containing 121
CCL22 chemokine (C-C motif) ligand 22
CCL27 chemokine (C-C motif) ligand 27
CCR7 chemokine (C-C motif) receptor 7
CD300C CD300c molecule
CDH5 cadherin 5, type 2 (vascular endothelium)
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CLSTN3 calsyntenin 3
COBL cordon-bleu WH2 repeat protein
COL5A1 collagen, type V, alpha 1
COMMD4 COMM domain containing 4
CYSLTR1 cysteinyl leukotriene receptor 1
DAPK2 death-associated protein kinase 2
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DGKQ diacylglycerol kinase, theta 110kDa
DIAPH2-AS1 DIAPH2 antisense RNA 1
DLX4 distal-less homeobox 4
DNAAF1 dynein, axonemal, assembly factor 1
DVL2 dishevelled segment polarity protein 2
EFCAB11 EF-hand calcium binding domain 11
ENPEP glutamyl aminopeptidase (aminopeptidase A)
FAM46C family with sequence similarity 46, member C
FAM63B family with sequence similarity 63, member B
FGFR2 fibroblast growth factor receptor 2
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FOXO4 forkhead box O4
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GRM4 glutamate receptor, metabotropic 4
HBE1 hemoglobin, epsilon 1
HNF4A hepatocyte nuclear factor 4, alpha
HOXB1 homeobox B1
HSPB6 heat shock protein, alpha-crystallin-related, B6
IDS iduronate 2-sulfatase
IL33R interleukin 33 receptor
ING2 inhibitor of growth family, member 2
KALRN kalirin, RhoGEF kinase
KIF21B kinesin family member 21B
KLF1 Kruppel-like factor 1 (erythroid)
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
LOC202181 SUMO-interacting motifs containing 1 pseudogene
MEFV Mediterranean fever
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
MMP12 matrix metallopeptidase 12
NPPB natriuretic peptide B
NPR1 natriuretic peptide receptor 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NRXN3 neurexin 3
OGG1 8-oxoguanine DNA glycosylase
PAX2 paired box 2
PCDH11Y protocadherin 11 Y-linked
PDE12 phosphodiesterase 12
PGLYRP4 peptidoglycan recognition protein 4
PLCH1 phospholipase C, eta 1
PLXDC1 plexin domain containing 1
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PROX1 prospero homeobox 1
PSG4 pregnancy specific beta-1-glycoprotein 4
PTCH2 patched 2
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
RASAL1 RAS protein activator like 1 (GAP1 like)
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
RGS1 regulator of G-protein signaling 1
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
RPS4Y1 ribosomal protein S4, Y-linked 1
RUNX1 runt-related transcription factor 1
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein
SERHL2 serine hydrolase-like 2
SH2D1A SH2 domain containing 1A
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
STK3 serine/threonine kinase 3
STS steroid sulfatase (microsomal), isozyme S
TCL6 T-cell leukemia/lymphoma 6 (non-protein coding)
THRB thyroid hormone receptor, beta
TMEM180 transmembrane protein 180
TONSL tonsoku-like, DNA repair protein
TP73-AS1 TP73 antisense RNA 1
TRIM10 tripartite motif containing 10
TRIM15 tripartite motif containing 15
TSPAN12 tetraspanin 12
TSPAN7 tetraspanin 7
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
UTS2 urotensin 2

decreased expression

Symbol Name
AGO4 argonaute RISC catalytic component 4
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ALS2CL ALS2 C-terminal like
ANKRD36B ankyrin repeat domain 36B
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARRB2 arrestin, beta 2
BAG4 BCL2-associated athanogene 4
BDNF brain-derived neurotrophic factor
BTC betacellulin
C22ORF29 chromosome 22 open reading frame 29
C4ORF19 chromosome 4 open reading frame 19
C4ORF29 chromosome 4 open reading frame 29
CAPN15 calpain 15
CCNJL cyclin J-like
CCS copper chaperone for superoxide dismutase
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDH7 cadherin 7, type 2
CENPO centromere protein O
CHM choroideremia (Rab escort protein 1)
CLDN14 claudin 14
CLSPN claspin
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CREB5 cAMP responsive element binding protein 5
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CSF1R colony stimulating factor 1 receptor
DBF4B DBF4 zinc finger B
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
EFNA3 ephrin-A3
EMP3 epithelial membrane protein 3
ERN2 endoplasmic reticulum to nucleus signaling 2
FAN1 FANCD2/FANCI-associated nuclease 1
FBXL6 F-box and leucine-rich repeat protein 6
FPGS folylpolyglutamate synthase
GINS4 GINS complex subunit 4 (Sld5 homolog)
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GPATCH2L G patch domain containing 2-like
GPR1 G protein-coupled receptor 1
GSTCD glutathione S-transferase, C-terminal domain containing
HDAC11 histone deacetylase 11
HIST1H2AK histone cluster 1, H2ak
IL4R interleukin 4 receptor
KIRREL kin of IRRE like (Drosophila)
MCMBP minichromosome maintenance complex binding protein
MDM4 MDM4, p53 regulator
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
MFSD12 major facilitator superfamily domain containing 12
MMP2 matrix metallopeptidase 2
MTG1 mitochondrial ribosome-associated GTPase 1
MXRA8 matrix-remodelling associated 8
MYL9 myosin, light chain 9, regulatory
ONECUT2 one cut homeobox 2
OSR2 odd-skipped related transciption factor 2
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PDE8B phosphodiesterase 8B
PDXDC1 pyridoxal-dependent decarboxylase domain containing 1
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLEKHO1 pleckstrin homology domain containing, family O member 1
PRSS8 protease, serine, 8
RAI2 retinoic acid induced 2
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RNF39 ring finger protein 39
RPP25 ribonuclease P/MRP 25kDa subunit
RUSC2 RUN and SH3 domain containing 2
SAYSD1 SAYSVFN motif domain containing 1
SEC14L2 SEC14-like 2 (S. cerevisiae)
SERGEF secretion regulating guanine nucleotide exchange factor
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STAC SH3 and cysteine rich domain
STARD5 StAR-related lipid transfer (START) domain containing 5
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TBC1D17 TBC1 domain family, member 17
TBX19 T-box 19
TBXAS1 thromboxane A synthase 1 (platelet)
TEP1 telomerase-associated protein 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TOM1 target of myb1 (chicken)
TOR4A torsin family 4, member A
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
UROS uroporphyrinogen III synthase
VNN1 vanin 1
WDR76 WD repeat domain 76
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZBTB22 zinc finger and BTB domain containing 22
ZFP30 ZFP30 zinc finger protein
ZNF286A zinc finger protein 286A
ZNF528 zinc finger protein 528
ZNF549 zinc finger protein 549
ZNF606 zinc finger protein 606
ZNF652 zinc finger protein 652