naproxen-1706 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the naproxen-1706 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD2 abhydrolase domain containing 2
ADM adrenomedullin
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
AP2B1 adaptor-related protein complex 2, beta 1 subunit
ARC activity-regulated cytoskeleton-associated protein
ARTN artemin
ASB1 ankyrin repeat and SOCS box containing 1
ATAD5 ATPase family, AAA domain containing 5
ATF6B activating transcription factor 6 beta
ATG3 autophagy related 3
ATP13A3 ATPase type 13A3
BCAM basal cell adhesion molecule (Lutheran blood group)
BIK BCL2-interacting killer (apoptosis-inducing)
BMP4 bone morphogenetic protein 4
C21ORF91 chromosome 21 open reading frame 91
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CCDC64 coiled-coil domain containing 64
CCDC93 coiled-coil domain containing 93
CD44 CD44 molecule (Indian blood group)
CD58 CD58 molecule
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CENPO centromere protein O
CEP350 centrosomal protein 350kDa
CHML choroideremia-like (Rab escort protein 2)
CKAP4 cytoskeleton-associated protein 4
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9
DOCK5 dedicator of cytokinesis 5
ENDOD1 endonuclease domain containing 1
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
F3 coagulation factor III (thromboplastin, tissue factor)
FBXO11 F-box protein 11
FBXO31 F-box protein 31
FBXO42 F-box protein 42
FKBP10 FK506 binding protein 10, 65 kDa
FLOT1 flotillin 1
G6PC3 glucose 6 phosphatase, catalytic, 3
GAN gigaxonin
GOLIM4 golgi integral membrane protein 4
GPRASP1 G protein-coupled receptor associated sorting protein 1
GSPT1 G1 to S phase transition 1
HEXA hexosaminidase A (alpha polypeptide)
HN1L hematological and neurological expressed 1-like
INO80B INO80 complex subunit B
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
IRF6 interferon regulatory factor 6
KIDINS220 kinase D-interacting substrate, 220kDa
KRAS Kirsten rat sarcoma viral oncogene homolog
LOC257152 uncharacterized LOC257152
MAP3K4 mitogen-activated protein kinase kinase kinase 4
MARCKS myristoylated alanine-rich protein kinase C substrate
MAX MYC associated factor X
NAIP NLR family, apoptosis inhibitory protein
NDE1 nudE neurodevelopment protein 1
NEK1 NIMA-related kinase 1
NF1 neurofibromin 1
NRF1 nuclear respiratory factor 1
PBX2 pre-B-cell leukemia homeobox 2
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PEX26 peroxisomal biogenesis factor 26
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLCG1 phospholipase C, gamma 1
PLK3 polo-like kinase 3
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PPP1R3D protein phosphatase 1, regulatory subunit 3D
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
PTCRA pre T-cell antigen receptor alpha
QRSL1 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1
RABEP2 rabaptin, RAB GTPase binding effector protein 2
RAD51B RAD51 paralog B
RAD52 RAD52 homolog (S. cerevisiae)
RANBP3 RAN binding protein 3
SCAMP1 secretory carrier membrane protein 1
SDC3 syndecan 3
SGK1 serum/glucocorticoid regulated kinase 1
SH2B1 SH2B adaptor protein 1
SLC35E2 solute carrier family 35, member E2
SLC48A1 solute carrier family 48 (heme transporter), member 1
SMC3 structural maintenance of chromosomes 3
SORT1 sortilin 1
SPIN1 spindlin 1
STK16 serine/threonine kinase 16
STRN striatin, calmodulin binding protein
STX7 syntaxin 7
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TH tyrosine hydroxylase
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TOP3A topoisomerase (DNA) III alpha
TPR translocated promoter region, nuclear basket protein
TSPAN9 tetraspanin 9
UBOX5 U-box domain containing 5
USO1 USO1 vesicle transport factor
WDTC1 WD and tetratricopeptide repeats 1
YTHDC1 YTH domain containing 1
ZNF747 zinc finger protein 747

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ABHD17B abhydrolase domain containing 17B
ACAD10 acyl-CoA dehydrogenase family, member 10
ADAT1 adenosine deaminase, tRNA-specific 1
ALPK1 alpha-kinase 1
ANP32A-IT1 ANP32A intronic transcript 1
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARRB2 arrestin, beta 2
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
BCAS1 breast carcinoma amplified sequence 1
BCL9 B-cell CLL/lymphoma 9
C11ORF30 chromosome 11 open reading frame 30
C1QTNF3 C1q and tumor necrosis factor related protein 3
CCDC170 coiled-coil domain containing 170
CCDC85C coiled-coil domain containing 85C
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CNR2 cannabinoid receptor 2 (macrophage)
DCAF10 DDB1 and CUL4 associated factor 10
DCP1A decapping mRNA 1A
DENND4C DENN/MADD domain containing 4C
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
ERCC4 excision repair cross-complementation group 4
FAM188A family with sequence similarity 188, member A
FBXW12 F-box and WD repeat domain containing 12
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FER fer (fps/fes related) tyrosine kinase
FGD1 FYVE, RhoGEF and PH domain containing 1
FLCN folliculin
GBP2 guanylate binding protein 2, interferon-inducible
GFOD1 glucose-fructose oxidoreductase domain containing 1
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GINS4 GINS complex subunit 4 (Sld5 homolog)
GNL1 guanine nucleotide binding protein-like 1
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
GUSBP3 glucuronidase, beta pseudogene 3
HAUS2 HAUS augmin-like complex, subunit 2
HYI hydroxypyruvate isomerase (putative)
IPP intracisternal A particle-promoted polypeptide
IRF2BP1 interferon regulatory factor 2 binding protein 1
IRF9 interferon regulatory factor 9
KIAA0894 KIAA0894 protein
KIF3B kinesin family member 3B
LARS leucyl-tRNA synthetase
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LOC390998 ribosomal protein L10 pseudogene
LRP5L low density lipoprotein receptor-related protein 5-like
LTBP2 latent transforming growth factor beta binding protein 2
MAP9 microtubule-associated protein 9
MAST4 microtubule associated serine/threonine kinase family member 4
MBTD1 mbt domain containing 1
MGC12488
NIPAL2 NIPA-like domain containing 2
NRSN2 neurensin 2
P3H1 prolyl 3-hydroxylase 1
PADI1 peptidyl arginine deiminase, type I
PC pyruvate carboxylase
PLIN3 perilipin 3
PMEL premelanosome protein
POLH polymerase (DNA directed), eta
POLR1B polymerase (RNA) I polypeptide B, 128kDa
PRPF19 pre-mRNA processing factor 19
PTPRU protein tyrosine phosphatase, receptor type, U
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RAPGEF6 Rap guanine nucleotide exchange factor (GEF) 6
RNF122 ring finger protein 122
RPAP1 RNA polymerase II associated protein 1
SCAI suppressor of cancer cell invasion
SETD8 SET domain containing (lysine methyltransferase) 8
SIDT1 SID1 transmembrane family, member 1
SP140L SP140 nuclear body protein-like
SPATA2L spermatogenesis associated 2-like
SREK1IP1 SREK1-interacting protein 1
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma)
STAG3L1 stromal antigen 3-like 1 (pseudogene)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TCTN1 tectonic family member 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM121 transmembrane protein 121
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TPCN1 two pore segment channel 1
TRAF2 TNF receptor-associated factor 2
TRIM16 tripartite motif containing 16
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae)
WDR76 WD repeat domain 76
WDR91 WD repeat domain 91
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZBTB39 zinc finger and BTB domain containing 39
ZNF160 zinc finger protein 160
ZNF205 zinc finger protein 205
ZNF430 zinc finger protein 430
ZNF510 zinc finger protein 510
ZNF652 zinc finger protein 652
ZNF696 zinc finger protein 696
ZNF721 zinc finger protein 721
ZNF778 zinc finger protein 778