| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the naproxen-1828 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 |
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) |
| ACACB | acetyl-CoA carboxylase beta |
| ADCY1 | adenylate cyclase 1 (brain) |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| AMDHD2 | amidohydrolase domain containing 2 |
| AMFR | autocrine motility factor receptor, E3 ubiquitin protein ligase |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| ATP10D | ATPase, class V, type 10D |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D |
| B3GNT4 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) |
| BEX4 | brain expressed, X-linked 4 |
| BICD1 | bicaudal D homolog 1 (Drosophila) |
| BMP2 | bone morphogenetic protein 2 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| C1ORF35 | chromosome 1 open reading frame 35 |
| C1ORF95 | chromosome 1 open reading frame 95 |
| CALML3 | calmodulin-like 3 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CCDC88A | coiled-coil domain containing 88A |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) |
| CDK3 | cyclin-dependent kinase 3 |
| CISH | cytokine inducible SH2-containing protein |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 |
| DEPDC5 | DEP domain containing 5 |
| EGFR | epidermal growth factor receptor |
| EIF4B | eukaryotic translation initiation factor 4B |
| EPOR | erythropoietin receptor |
| FAM222B | family with sequence similarity 222, member B |
| FGF1 | fibroblast growth factor 1 (acidic) |
| FMO4 | flavin containing monooxygenase 4 |
| FNBP1 | formin binding protein 1 |
| FOXN3 | forkhead box N3 |
| GPR3 | G protein-coupled receptor 3 |
| GRIP2 | glutamate receptor interacting protein 2 |
| HIST1H3G | histone cluster 1, H3g |
| HOXC8 | homeobox C8 |
| HRG | histidine-rich glycoprotein |
| IGF1R | insulin-like growth factor 1 receptor |
| IL6ST | interleukin 6 signal transducer |
| ISG20L2 | interferon stimulated exonuclease gene 20kDa-like 2 |
| ITGB5 | integrin, beta 5 |
| KCNJ8 | potassium channel, inwardly rectifying subfamily J, member 8 |
| LRP6 | low density lipoprotein receptor-related protein 6 |
| MAP3K7CL | MAP3K7 C-terminal like |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 |
| MFNG | MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| MKL1 | megakaryoblastic leukemia (translocation) 1 |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| MUC3B | mucin 3B, cell surface associated |
| MXD4 | MAX dimerization protein 4 |
| MYL10 | myosin, light chain 10, regulatory |
| MYOZ1 | myozenin 1 |
| NCOA3 | nuclear receptor coactivator 3 |
| NUDT11 | nudix (nucleoside diphosphate linked moiety X)-type motif 11 |
| PADI1 | peptidyl arginine deiminase, type I |
| PEX26 | peroxisomal biogenesis factor 26 |
| PHF20 | PHD finger protein 20 |
| PIAS1 | protein inhibitor of activated STAT, 1 |
| PLK3 | polo-like kinase 3 |
| PRR15L | proline rich 15-like |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| PTGES | prostaglandin E synthase |
| RAB11B | RAB11B, member RAS oncogene family |
| RAI2 | retinoic acid induced 2 |
| RDH11 | retinol dehydrogenase 11 (all-trans/9-cis/11-cis) |
| RUNX1 | runt-related transcription factor 1 |
| S1PR1 | sphingosine-1-phosphate receptor 1 |
| SARS2 | seryl-tRNA synthetase 2, mitochondrial |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) |
| SF1 | splicing factor 1 |
| SLC11A2 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 |
| SPTB | spectrin, beta, erythrocytic |
| SURF1 | surfeit 1 |
| SYN2 | synapsin II |
| SYNJ1 | synaptojanin 1 |
| TBC1D30 | TBC1 domain family, member 30 |
| TBC1D4 | TBC1 domain family, member 4 |
| TCAF1 | TRPM8 channel-associated factor 1 |
| TCF3 | transcription factor 3 |
| TJP3 | tight junction protein 3 |
| TLN2 | talin 2 |
| TXNRD3 | thioredoxin reductase 3 |
| USF2 | upstream transcription factor 2, c-fos interacting |
| VGLL3 | vestigial-like family member 3 |
| WDTC1 | WD and tetratricopeptide repeats 1 |
| WNT2 | wingless-type MMTV integration site family member 2 |
| ZCCHC4 | zinc finger, CCHC domain containing 4 |
| ZNF236 | zinc finger protein 236 |
| ZNF552 | zinc finger protein 552 |
| ZNF609 | zinc finger protein 609 |
| ZNF629 | zinc finger protein 629 |
| ZNF75D | zinc finger protein 75D |
| Symbol | Name |
|---|---|
| ACSF2 | acyl-CoA synthetase family member 2 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| AP4M1 | adaptor-related protein complex 4, mu 1 subunit |
| ARF5 | ADP-ribosylation factor 5 |
| ASTE1 | asteroid homolog 1 (Drosophila) |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| BCKDK | branched chain ketoacid dehydrogenase kinase |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 |
| BSCL2 | Berardinelli-Seip congenital lipodystrophy 2 (seipin) |
| BSG | basigin (Ok blood group) |
| BTBD2 | BTB (POZ) domain containing 2 |
| CFD | complement factor D (adipsin) |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHMP6 | charged multivesicular body protein 6 |
| CHMP7 | charged multivesicular body protein 7 |
| CLIP2 | CAP-GLY domain containing linker protein 2 |
| CNPY3 | canopy FGF signaling regulator 3 |
| CPSF3L | cleavage and polyadenylation specific factor 3-like |
| CRABP2 | cellular retinoic acid binding protein 2 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DPM2 | dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit |
| EFNA3 | ephrin-A3 |
| ETAA1 | Ewing tumor-associated antigen 1 |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FKBPL | FK506 binding protein like |
| FPGS | folylpolyglutamate synthase |
| FZD8 | frizzled class receptor 8 |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GLI3 | GLI family zinc finger 3 |
| GTF2F2 | general transcription factor IIF, polypeptide 2, 30kDa |
| HAUS6 | HAUS augmin-like complex, subunit 6 |
| HDAC7 | histone deacetylase 7 |
| HMBOX1 | homeobox containing 1 |
| HSD17B7 | hydroxysteroid (17-beta) dehydrogenase 7 |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| ISYNA1 | inositol-3-phosphate synthase 1 |
| KIAA0894 | KIAA0894 protein |
| KIZ | kizuna centrosomal protein |
| LHX6 | LIM homeobox 6 |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 |
| LRRC37A2 | leucine rich repeat containing 37, member A2 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MB | myoglobin |
| MMS19 | MMS19 nucleotide excision repair homolog (S. cerevisiae) |
| MOGS | mannosyl-oligosaccharide glucosidase |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like |
| MYO1D | myosin ID |
| NARFL | nuclear prelamin A recognition factor-like |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NRBP1 | nuclear receptor binding protein 1 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| P3H4 | prolyl 3-hydroxylase family member 4 (non-enzymatic) |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PHKG2 | phosphorylase kinase, gamma 2 (testis) |
| POLD1 | polymerase (DNA directed), delta 1, catalytic subunit |
| POLD4 | polymerase (DNA-directed), delta 4, accessory subunit |
| POLR2J2 | polymerase (RNA) II (DNA directed) polypeptide J2 |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) |
| PPP2R2D | protein phosphatase 2, regulatory subunit B, delta |
| PPRC1 | peroxisome proliferator-activated receptor gamma, coactivator-related 1 |
| PTK6 | protein tyrosine kinase 6 |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RBM38 | RNA binding motif protein 38 |
| RBM42 | RNA binding motif protein 42 |
| RNF25 | ring finger protein 25 |
| RPGR | retinitis pigmentosa GTPase regulator |
| S100A4 | S100 calcium binding protein A4 |
| SETMAR | SET domain and mariner transposase fusion gene |
| SIPA1 | signal-induced proliferation-associated 1 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SLC3A2 | solute carrier family 3 (amino acid transporter heavy chain), member 2 |
| SLC41A3 | solute carrier family 41, member 3 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SNRNP35 | small nuclear ribonucleoprotein 35kDa (U11/U12) |
| SPAG4 | sperm associated antigen 4 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 |
| STX5 | syntaxin 5 |
| SUGP1 | SURP and G patch domain containing 1 |
| SYNPO | synaptopodin |
| TARBP2 | TAR (HIV-1) RNA binding protein 2 |
| TH | tyrosine hydroxylase |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein |
| UBE2O | ubiquitin-conjugating enzyme E2O |
| UBXN8 | UBX domain protein 8 |
| ULBP2 | UL16 binding protein 2 |
| WDR18 | WD repeat domain 18 |
| XAB2 | XPA binding protein 2 |
| XPC | xeroderma pigmentosum, complementation group C |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF160 | zinc finger protein 160 |
| ZNF267 | zinc finger protein 267 |
| ZNF430 | zinc finger protein 430 |
| ZNF654 | zinc finger protein 654 |
| ZSCAN31 | zinc finger and SCAN domain containing 31 |