| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the naproxen-1869 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACVR1B | activin A receptor, type IB |
| ALK | anaplastic lymphoma receptor tyrosine kinase |
| ALS2CL | ALS2 C-terminal like |
| ANO10 | anoctamin 10 |
| APOC1 | apolipoprotein C-I |
| APPL2 | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 |
| ARFRP1 | ADP-ribosylation factor related protein 1 |
| ART1 | ADP-ribosyltransferase 1 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B |
| BMP1 | bone morphogenetic protein 1 |
| BMP7 | bone morphogenetic protein 7 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CCDC71 | coiled-coil domain containing 71 |
| CCS | copper chaperone for superoxide dismutase |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) |
| CDH8 | cadherin 8, type 2 |
| COA7 | cytochrome c oxidase assembly factor 7 (putative) |
| CXCR3 | chemokine (C-X-C motif) receptor 3 |
| DEAF1 | DEAF1 transcription factor |
| DHRS11 | dehydrogenase/reductase (SDR family) member 11 |
| DMTN | dematin actin binding protein |
| DSTYK | dual serine/threonine and tyrosine protein kinase |
| EFEMP2 | EGF containing fibulin-like extracellular matrix protein 2 |
| FAM214B | family with sequence similarity 214, member B |
| FAM65A | family with sequence similarity 65, member A |
| GOLGA1 | golgin A1 |
| GPR3 | G protein-coupled receptor 3 |
| HAAO | 3-hydroxyanthranilate 3,4-dioxygenase |
| HCFC1R1 | host cell factor C1 regulator 1 (XPO1 dependent) |
| HDAC7 | histone deacetylase 7 |
| HIGD2A | HIG1 hypoxia inducible domain family, member 2A |
| HK2 | hexokinase 2 |
| HSPA4 | heat shock 70kDa protein 4 |
| IDH3G | isocitrate dehydrogenase 3 (NAD+) gamma |
| ITGB4 | integrin, beta 4 |
| IZUMO4 | IZUMO family member 4 |
| JAG2 | jagged 2 |
| JUP | junction plakoglobin |
| KCNAB2 | potassium channel, voltage gated subfamily A regulatory beta subunit 2 |
| KCNQ1 | potassium channel, voltage gated KQT-like subfamily Q, member 1 |
| KIAA0355 | KIAA0355 |
| KRIT1 | KRIT1, ankyrin repeat containing |
| LIPG | lipase, endothelial |
| LPAR1 | lysophosphatidic acid receptor 1 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MAP4 | microtubule-associated protein 4 |
| MAPK7 | mitogen-activated protein kinase 7 |
| MAX | MYC associated factor X |
| MYOF | myoferlin |
| NCOA1 | nuclear receptor coactivator 1 |
| NCR2 | natural cytotoxicity triggering receptor 2 |
| NCS1 | neuronal calcium sensor 1 |
| NEBL | nebulette |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 |
| NRP1 | neuropilin 1 |
| OGFR | opioid growth factor receptor |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 |
| PHACTR1 | phosphatase and actin regulator 1 |
| PHTF2 | putative homeodomain transcription factor 2 |
| PKD1 | polycystic kidney disease 1 (autosomal dominant) |
| POFUT1 | protein O-fucosyltransferase 1 |
| PQBP1 | polyglutamine binding protein 1 |
| PRKAR2A | protein kinase, cAMP-dependent, regulatory, type II, alpha |
| PRPF6 | pre-mRNA processing factor 6 |
| PVRL2 | poliovirus receptor-related 2 (herpesvirus entry mediator B) |
| RAB13 | RAB13, member RAS oncogene family |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RAP1GAP | RAP1 GTPase activating protein |
| REST | RE1-silencing transcription factor |
| RPL10 | ribosomal protein L10 |
| RUNX1 | runt-related transcription factor 1 |
| SEC14L1 | SEC14-like 1 (S. cerevisiae) |
| SGSM3 | small G protein signaling modulator 3 |
| SMC3 | structural maintenance of chromosomes 3 |
| SOX15 | SRY (sex determining region Y)-box 15 |
| SPN | sialophorin |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 |
| TAPBP | TAP binding protein (tapasin) |
| TAT | tyrosine aminotransferase |
| TBC1D17 | TBC1 domain family, member 17 |
| TBL1X | transducin (beta)-like 1X-linked |
| TECPR2 | tectonin beta-propeller repeat containing 2 |
| TGM5 | transglutaminase 5 |
| TNNT1 | troponin T type 1 (skeletal, slow) |
| USP22 | ubiquitin specific peptidase 22 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) |
| VARS | valyl-tRNA synthetase |
| WDR76 | WD repeat domain 76 |
| ZNF324 | zinc finger protein 324 |
| ZNF345 | zinc finger protein 345 |
| ZNF710 | zinc finger protein 710 |
| ZNF783 | zinc finger family member 783 |
| ZNF816 | zinc finger protein 816 |
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| ADGRA3 | adhesion G protein-coupled receptor A3 |
| AHCTF1 | AT hook containing transcription factor 1 |
| ANXA3 | annexin A3 |
| APH1B | APH1B gamma secretase subunit |
| ASTE1 | asteroid homolog 1 (Drosophila) |
| C11ORF95 | chromosome 11 open reading frame 95 |
| C12ORF49 | chromosome 12 open reading frame 49 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| C5AR1 | complement component 5a receptor 1 |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| CLDN15 | claudin 15 |
| CLK1 | CDC-like kinase 1 |
| COG7 | component of oligomeric golgi complex 7 |
| COL9A2 | collagen, type IX, alpha 2 |
| CPNE7 | copine VII |
| CRY1 | cryptochrome circadian clock 1 |
| CSF1R | colony stimulating factor 1 receptor |
| CYP2R1 | cytochrome P450, family 2, subfamily R, polypeptide 1 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| DHX35 | DEAH (Asp-Glu-Ala-His) box polypeptide 35 |
| ETAA1 | Ewing tumor-associated antigen 1 |
| FAM184A | family with sequence similarity 184, member A |
| FAM204A | family with sequence similarity 204, member A |
| FAM63A | family with sequence similarity 63, member A |
| FBXL12 | F-box and leucine-rich repeat protein 12 |
| FCHO1 | FCH domain only 1 |
| FICD | FIC domain containing |
| FKBP9 | FK506 binding protein 9, 63 kDa |
| FMNL1 | formin-like 1 |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GPR65 | G protein-coupled receptor 65 |
| GPR85 | G protein-coupled receptor 85 |
| GTF2I | general transcription factor IIi |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HCAR3 | hydroxycarboxylic acid receptor 3 |
| HIST1H2BI | histone cluster 1, H2bi |
| HIST1H4J | histone cluster 1, H4j |
| IFI44L | interferon-induced protein 44-like |
| IL18 | interleukin 18 |
| KCNMB1 | potassium channel subfamily M regulatory beta subunit 1 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KIF13B | kinesin family member 13B |
| LAIR2 | leukocyte-associated immunoglobulin-like receptor 2 |
| LOC157562 | uncharacterized LOC157562 |
| MANEA | mannosidase, endo-alpha |
| MOGS | mannosyl-oligosaccharide glucosidase |
| MRGBP | MRG/MORF4L binding protein |
| MTERF1 | mitochondrial transcription termination factor 1 |
| MUM1 | melanoma associated antigen (mutated) 1 |
| MYL12B | myosin, light chain 12B, regulatory |
| NARFL | nuclear prelamin A recognition factor-like |
| NME3 | NME/NM23 nucleoside diphosphate kinase 3 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PARG | poly (ADP-ribose) glycohydrolase |
| PARPBP | PARP1 binding protein |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PDGFD | platelet derived growth factor D |
| PFAS | phosphoribosylformylglycinamidine synthase |
| PIP4K2C | phosphatidylinositol-5-phosphate 4-kinase, type II, gamma |
| PJA1 | praja ring finger 1, E3 ubiquitin protein ligase |
| POMZP3 | POM121 and ZP3 fusion |
| PROCR | protein C receptor, endothelial |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RAB17 | RAB17, member RAS oncogene family |
| REEP4 | receptor accessory protein 4 |
| RNF141 | ring finger protein 141 |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 |
| RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 |
| SCAMP3 | secretory carrier membrane protein 3 |
| SNHG20 | small nucleolar RNA host gene 20 |
| SNHG3 | small nucleolar RNA host gene 3 |
| SNRPN | small nuclear ribonucleoprotein polypeptide N |
| SOHLH2 | spermatogenesis and oogenesis specific basic helix-loop-helix 2 |
| SREBF1 | sterol regulatory element binding transcription factor 1 |
| TBX19 | T-box 19 |
| TCTN1 | tectonic family member 1 |
| TGFBR3 | transforming growth factor, beta receptor III |
| THEM6 | thioesterase superfamily member 6 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TMEM209 | transmembrane protein 209 |
| TMEM242 | transmembrane protein 242 |
| TMEM8A | transmembrane protein 8A |
| TRIM9 | tripartite motif containing 9 |
| TTI2 | TELO2 interacting protein 2 |
| TTPAL | tocopherol (alpha) transfer protein-like |
| UBQLN4 | ubiquilin 4 |
| UNKL | unkempt family zinc finger-like |
| WDR19 | WD repeat domain 19 |
| WT1-AS | WT1 antisense RNA |
| XAF1 | XIAP associated factor 1 |
| ZNF443 | zinc finger protein 443 |
| ZNF675 | zinc finger protein 675 |
| ZNF85 | zinc finger protein 85 |
| ZNF862 | zinc finger protein 862 |