naproxen-5457 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

197 genes differentially expressed following the naproxen-5457 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AGFG2 ArfGAP with FG repeats 2
APAF1 apoptotic peptidase activating factor 1
ARC activity-regulated cytoskeleton-associated protein
ARSD arylsulfatase D
ASPH aspartate beta-hydroxylase
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C3 complement component 3
C4ORF29 chromosome 4 open reading frame 29
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CD36 CD36 molecule (thrombospondin receptor)
CDK19 cyclin-dependent kinase 19
CFLAR CASP8 and FADD-like apoptosis regulator
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CLDN11 claudin 11
CLEC1B C-type lectin domain family 1, member B
CLGN calmegin
COMT catechol-O-methyltransferase
CREM cAMP responsive element modulator
CRTC1 CREB regulated transcription coactivator 1
CRYGC crystallin, gamma C
CXORF21 chromosome X open reading frame 21
DAAM2 dishevelled associated activator of morphogenesis 2
DOCK9 dedicator of cytokinesis 9
EHD2 EH-domain containing 2
ELSPBP1 epididymal sperm binding protein 1
ERAP1 endoplasmic reticulum aminopeptidase 1
ETV6 ets variant 6
FAM214B family with sequence similarity 214, member B
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FGF6 fibroblast growth factor 6
FGFR1 fibroblast growth factor receptor 1
FRZB frizzled-related protein
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GK glycerol kinase
GOSR1 golgi SNAP receptor complex member 1
HDAC6 histone deacetylase 6
HUS1 HUS1 checkpoint homolog (S. pombe)
ICA1 islet cell autoantigen 1, 69kDa
ING4 inhibitor of growth family, member 4
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KCNK5 potassium channel, two pore domain subfamily K, member 5
KIAA0319L KIAA0319-like
KRT15 keratin 15, type I
KYNU kynureninase
LMAN1 lectin, mannose-binding, 1
LMBR1L limb development membrane protein 1-like
LOC644450 uncharacterized LOC644450
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MAP4 microtubule-associated protein 4
MAPK14 mitogen-activated protein kinase 14
MFSD7 major facilitator superfamily domain containing 7
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MST1 macrophage stimulating 1
MUC4 mucin 4, cell surface associated
NBL1 neuroblastoma 1, DAN family BMP antagonist
NMT2 N-myristoyltransferase 2
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
PAIP2B poly(A) binding protein interacting protein 2B
PAPPA2 pappalysin 2
PCM1 pericentriolar material 1
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa
PDIA2 protein disulfide isomerase family A, member 2
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLEKHO2 pleckstrin homology domain containing, family O member 2
RABEP2 rabaptin, RAB GTPase binding effector protein 2
RASAL2 RAS protein activator like 2
RGS17 regulator of G-protein signaling 17
RGS4 regulator of G-protein signaling 4
RHAG Rh-associated glycoprotein
RNF208 ring finger protein 208
RNMT RNA (guanine-7-) methyltransferase
RPL35A ribosomal protein L35a
RPS2 ribosomal protein S2
RUNX1 runt-related transcription factor 1
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2
SGCE sarcoglycan, epsilon
SKA1 spindle and kinetochore associated complex subunit 1
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SLPI secretory leukocyte peptidase inhibitor
STK17B serine/threonine kinase 17b
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
TACC1 transforming, acidic coiled-coil containing protein 1
TBC1D22A TBC1 domain family, member 22A
TBX1 T-box 1
TCP11L1 t-complex 11, testis-specific-like 1
TFF2 trefoil factor 2
TICAM1 toll-like receptor adaptor molecule 1
TRIM3 tripartite motif containing 3
UPK3B uroplakin 3B
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
ZBTB22 zinc finger and BTB domain containing 22
ZNF235 zinc finger protein 235
ZNF287 zinc finger protein 287
ZNF750 zinc finger protein 750

decreased expression

Symbol Name
ACBD4 acyl-CoA binding domain containing 4
ACTG2 actin, gamma 2, smooth muscle, enteric
ACTL8 actin-like 8
ADGRE5 adhesion G protein-coupled receptor E5
ALDOC aldolase C, fructose-bisphosphate
ATP10D ATPase, class V, type 10D
B9D2 B9 protein domain 2
BBC3 BCL2 binding component 3
BTF3P12 basic transcription factor 3 pseudogene 12
C10ORF95 chromosome 10 open reading frame 95
C7ORF43 chromosome 7 open reading frame 43
CCNO cyclin O
CD83 CD83 molecule
CDON cell adhesion associated, oncogene regulated
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CST6 cystatin E/M
DNAH17 dynein, axonemal, heavy chain 17
DOC2A double C2-like domains, alpha
DSPP dentin sialophosphoprotein
ERN2 endoplasmic reticulum to nucleus signaling 2
FBXO4 F-box protein 4
FGD1 FYVE, RhoGEF and PH domain containing 1
FOSL1 FOS-like antigen 1
GLRA1 glycine receptor, alpha 1
GPATCH2L G patch domain containing 2-like
GPNMB glycoprotein (transmembrane) nmb
GRB7 growth factor receptor-bound protein 7
GTPBP2 GTP binding protein 2
HHAT hedgehog acyltransferase
HIST1H2AJ histone cluster 1, H2aj
HIST1H2AL histone cluster 1, H2al
HIST1H3E histone cluster 1, H3e
HIST1H4A histone cluster 1, H4a
HLA-DMB major histocompatibility complex, class II, DM beta
HOXC10 homeobox C10
IDI2-AS1 IDI2 antisense RNA 1
IFT140 intraflagellar transport 140
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IRF1 interferon regulatory factor 1
ITGA10 integrin, alpha 10
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
KLHL25 kelch-like family member 25
KLRG1 killer cell lectin-like receptor subfamily G, member 1
LAMC3 laminin, gamma 3
LHX1 LIM homeobox 1
MEFV Mediterranean fever
MRPL41 mitochondrial ribosomal protein L41
NDE1 nudE neurodevelopment protein 1
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NPIPB15 nuclear pore complex interacting protein family, member B15
PCDHB3 protocadherin beta 3
PCDHGA10 protocadherin gamma subfamily A, 10
PCDHGB5 protocadherin gamma subfamily B, 5
PDE12 phosphodiesterase 12
PDE8B phosphodiesterase 8B
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PODNL1 podocan-like 1
PRICKLE3 prickle homolog 3 (Drosophila)
PRODH proline dehydrogenase (oxidase) 1
PSG4 pregnancy specific beta-1-glycoprotein 4
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RFXAP regulatory factor X-associated protein
RIBC2 RIB43A domain with coiled-coils 2
RNF39 ring finger protein 39
RUSC2 RUN and SH3 domain containing 2
S100A9 S100 calcium binding protein A9
SCN10A sodium channel, voltage gated, type X alpha subunit
SCN1B sodium channel, voltage gated, type I beta subunit
SDC3 syndecan 3
SLC12A8 solute carrier family 12, member 8
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC41A3 solute carrier family 41, member 3
SMIM14 small integral membrane protein 14
SRPX sushi-repeat containing protein, X-linked
STAG3 stromal antigen 3
STARD13 StAR-related lipid transfer (START) domain containing 13
STEAP1 six transmembrane epithelial antigen of the prostate 1
STEAP4 STEAP family member 4
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAOK1 TAO kinase 1
TBL1Y transducin (beta)-like 1, Y-linked
TBX19 T-box 19
TESC tescalcin
TET3 tet methylcytosine dioxygenase 3
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TNS2 tensin 2
TSGA10 testis specific, 10
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
USP20 ubiquitin specific peptidase 20
VEGFC vascular endothelial growth factor C
VIM vimentin
WNT16 wingless-type MMTV integration site family, member 16
ZNF205 zinc finger protein 205
ZNF446 zinc finger protein 446
ZNF606 zinc finger protein 606
ZNF665 zinc finger protein 665
ZNF701 zinc finger protein 701