| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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194 genes differentially expressed following the naproxen-6096 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACAA2 | acetyl-CoA acyltransferase 2 |
| ADAMTS13 | ADAM metallopeptidase with thrombospondin type 1 motif, 13 |
| ADCK4 | aarF domain containing kinase 4 |
| ADCY7 | adenylate cyclase 7 |
| ADH7 | alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide |
| ADRA1D | adrenoceptor alpha 1D |
| AKAP1 | A kinase (PRKA) anchor protein 1 |
| AMPD1 | adenosine monophosphate deaminase 1 |
| ANXA2P3 | annexin A2 pseudogene 3 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 |
| ASB1 | ankyrin repeat and SOCS box containing 1 |
| C10ORF10 | chromosome 10 open reading frame 10 |
| C4BPA | complement component 4 binding protein, alpha |
| CA5B | carbonic anhydrase VB, mitochondrial |
| CD4 | CD4 molecule |
| CD6 | CD6 molecule |
| CDHR2 | cadherin-related family member 2 |
| CEP112 | centrosomal protein 112kDa |
| CMAHP | cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene |
| COMP | cartilage oligomeric matrix protein |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 |
| EDN1 | endothelin 1 |
| EPN1 | epsin 1 |
| FBXO24 | F-box protein 24 |
| FBXO4 | F-box protein 4 |
| FOXF1 | forkhead box F1 |
| FSHB | follicle stimulating hormone, beta polypeptide |
| FUT3 | fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GLP1R | glucagon-like peptide 1 receptor |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HR | hair growth associated |
| IFT54 | intraflagellar transport 54 |
| IL11 | interleukin 11 |
| IL2RB | interleukin 2 receptor, beta |
| KCNK10 | potassium channel, two pore domain subfamily K, member 10 |
| KLHL11 | kelch-like family member 11 |
| KLHL35 | kelch-like family member 35 |
| KRT75 | keratin 75, type II |
| LAG3 | lymphocyte-activation gene 3 |
| LAMP1 | lysosomal-associated membrane protein 1 |
| LEF1 | lymphoid enhancer-binding factor 1 |
| LIF | leukemia inhibitory factor |
| LLGL1 | lethal giant larvae homolog 1 (Drosophila) |
| LLPH | LLP homolog, long-term synaptic facilitation (Aplysia) |
| LRRC23 | leucine rich repeat containing 23 |
| LY9 | lymphocyte antigen 9 |
| MED25 | mediator complex subunit 25 |
| MFSD6 | major facilitator superfamily domain containing 6 |
| MLLT4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming |
| MUC6 | mucin 6, oligomeric mucus/gel-forming |
| MYF5 | myogenic factor 5 |
| NCOR2 | nuclear receptor corepressor 2 |
| NKX6-1 | NK6 homeobox 1 |
| NPC1 | Niemann-Pick disease, type C1 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 |
| NRG1 | neuregulin 1 |
| NSUN6 | NOP2/Sun domain family, member 6 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa |
| OBSCN | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF |
| PDPN | podoplanin |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| PTPRJ | protein tyrosine phosphatase, receptor type, J |
| PTTG2 | pituitary tumor-transforming 2 |
| RAB3B | RAB3B, member RAS oncogene family |
| RGS12 | regulator of G-protein signaling 12 |
| RHBG | Rh family, B glycoprotein (gene/pseudogene) |
| RPH3A | rabphilin 3A |
| RPL35A | ribosomal protein L35a |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| SH3BP2 | SH3-domain binding protein 2 |
| SHMT1 | serine hydroxymethyltransferase 1 (soluble) |
| SLC17A7 | solute carrier family 17 (vesicular glutamate transporter), member 7 |
| SLC30A3 | solute carrier family 30 (zinc transporter), member 3 |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 |
| SPTB | spectrin, beta, erythrocytic |
| SPTBN5 | spectrin, beta, non-erythrocytic 5 |
| SRF | serum response factor (c-fos serum response element-binding transcription factor) |
| TAGLN3 | transgelin 3 |
| TM4SF5 | transmembrane 4 L six family member 5 |
| TP63 | tumor protein p63 |
| TRPM3 | transient receptor potential cation channel, subfamily M, member 3 |
| TSPAN2 | tetraspanin 2 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| WFDC8 | WAP four-disulfide core domain 8 |
| ZNF484 | zinc finger protein 484 |
| ZNF639 | zinc finger protein 639 |
| ZNF646 | zinc finger protein 646 |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 |
| Symbol | Name |
|---|---|
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| AMT | aminomethyltransferase |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| C2ORF54 | chromosome 2 open reading frame 54 |
| C3ORF18 | chromosome 3 open reading frame 18 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CAPRIN2 | caprin family member 2 |
| CDKN2D | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) |
| CEACAM4 | carcinoembryonic antigen-related cell adhesion molecule 4 |
| CFAP69 | cilia and flagella associated protein 69 |
| CHRNA6 | cholinergic receptor, nicotinic, alpha 6 (neuronal) |
| CORO7 | coronin 7 |
| CRMP1 | collapsin response mediator protein 1 |
| CRYGC | crystallin, gamma C |
| CUL9 | cullin 9 |
| DBF4B | DBF4 zinc finger B |
| DEF6 | differentially expressed in FDCP 6 homolog (mouse) |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DRD1 | dopamine receptor D1 |
| DUSP9 | dual specificity phosphatase 9 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| FAM189A2 | family with sequence similarity 189, member A2 |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FGGY | FGGY carbohydrate kinase domain containing |
| FLJ11710 | uncharacterized protein FLJ11710 |
| GAMT | guanidinoacetate N-methyltransferase |
| GPATCH2L | G patch domain containing 2-like |
| GRB7 | growth factor receptor-bound protein 7 |
| HAO2 | hydroxyacid oxidase 2 (long chain) |
| HDAC11 | histone deacetylase 11 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HIST1H2BJ | histone cluster 1, H2bj |
| HOXB2 | homeobox B2 |
| HOXC8 | homeobox C8 |
| HSD17B1 | hydroxysteroid (17-beta) dehydrogenase 1 |
| INO80D | INO80 complex subunit D |
| INPP5J | inositol polyphosphate-5-phosphatase J |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KLHL28 | kelch-like family member 28 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LAX1 | lymphocyte transmembrane adaptor 1 |
| LENEP | lens epithelial protein |
| LOC729164 | hCG1732469 |
| MAGI1 | membrane associated guanylate kinase, WW and PDZ domain containing 1 |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MYLK | myosin light chain kinase |
| NDOR1 | NADPH dependent diflavin oxidoreductase 1 |
| NECAB2 | N-terminal EF-hand calcium binding protein 2 |
| NKX3-2 | NK3 homeobox 2 |
| NPTX1 | neuronal pentraxin I |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| OSMR | oncostatin M receptor |
| PCDH12 | protocadherin 12 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PDE12 | phosphodiesterase 12 |
| PDGFD | platelet derived growth factor D |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 |
| PIGN | phosphatidylinositol glycan anchor biosynthesis, class N |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| PMCHL1 | pro-melanin-concentrating hormone-like 1, pseudogene |
| PORCN | porcupine homolog (Drosophila) |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| RAB40AL | RAB40A, member RAS oncogene family-like |
| RAB40C | RAB40C, member RAS oncogene family |
| RAPSN | receptor-associated protein of the synapse |
| RFXAP | regulatory factor X-associated protein |
| ROBO3 | roundabout, axon guidance receptor, homolog 3 (Drosophila) |
| RPL10L | ribosomal protein L10-like |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SLPI | secretory leukocyte peptidase inhibitor |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| STAB2 | stabilin 2 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 |
| TIGD6 | tigger transposable element derived 6 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| TMEM242 | transmembrane protein 242 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TRIM36 | tripartite motif containing 36 |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| UPP1 | uridine phosphorylase 1 |
| XDH | xanthine dehydrogenase |
| ZNF10 | zinc finger protein 10 |
| ZNF205 | zinc finger protein 205 |
| ZNF219 | zinc finger protein 219 |
| ZNF329 | zinc finger protein 329 |
| ZNF350 | zinc finger protein 350 |
| ZNF532 | zinc finger protein 532 |