narcolepsy Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A sleep disorder that involves an excessive urge to sleep at inappropriate times, such as while at work. (Human Disease Ontology, DOID_8986)
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Genes

213 genes associated with the disease narcolepsy in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ACOX3 acyl-CoA oxidase 3, pristanoyl
ACVR1 activin A receptor, type I
ADAM10 ADAM metallopeptidase domain 10
ADCY8 adenylate cyclase 8 (brain)
ADGRA3 adhesion G protein-coupled receptor A3
ADGRB2 adhesion G protein-coupled receptor B2
ADGRB3 adhesion G protein-coupled receptor B3
ADGRG6 adhesion G protein-coupled receptor G6
ADGRL3 adhesion G protein-coupled receptor L3
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
AIMP1P1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 pseudogene 1
AKAP1 A kinase (PRKA) anchor protein 1
AKAP6 A kinase (PRKA) anchor protein 6
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
ALOX15B arachidonate 15-lipoxygenase, type B
ALOX5 arachidonate 5-lipoxygenase
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ASB13 ankyrin repeat and SOCS box containing 13
ASIC2 acid sensing (proton gated) ion channel 2
BAAT bile acid CoA:amino acid N-acyltransferase
BAG1 BCL2-associated athanogene
BCAP29 B-cell receptor-associated protein 29
BCL2L14 BCL2-like 14 (apoptosis facilitator)
BMP2 bone morphogenetic protein 2
BMP7 bone morphogenetic protein 7
BNIP2 BCL2/adenovirus E1B 19kDa interacting protein 2
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CACNB2 calcium channel, voltage-dependent, beta 2 subunit
CADM1 cell adhesion molecule 1
CAMK1D calcium/calmodulin-dependent protein kinase ID
CAMK4 calcium/calmodulin-dependent protein kinase IV
CASP8 caspase 8, apoptosis-related cysteine peptidase
CCL2 chemokine (C-C motif) ligand 2
CCND2 cyclin D2
CCNG2 cyclin G2
CCRL2 chemokine (C-C motif) receptor-like 2
CD14 CD14 molecule
CD274 CD274 molecule
CDK5RAP1 CDK5 regulatory subunit associated protein 1
CDKN3 cyclin-dependent kinase inhibitor 3
CELF2 CUGBP, Elav-like family member 2
CERKL ceramide kinase-like
CGRRF1 cell growth regulator with ring finger domain 1
CHES1L1 checkpoint suppressor 1-like 1
CHKB choline kinase beta
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
COMT catechol-O-methyltransferase
CPT1B carnitine palmitoyltransferase 1B (muscle)
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CRAT carnitine O-acetyltransferase
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1
CWF19L2 CWF19-like 2, cell cycle control (S. pombe)
CYLC2 cylicin, basic protein of sperm head cytoskeleton 2
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
DAD1 defender against cell death 1
DAPK1 death-associated protein kinase 1
DCC DCC netrin 1 receptor
DEGS2 delta(4)-desaturase, sphingolipid 2
DGKB diacylglycerol kinase, beta 90kDa
DNAJB13 DnaJ (Hsp40) homolog, subfamily B, member 13
DOC2A double C2-like domains, alpha
DRD1 dopamine receptor D1
DRD2 dopamine receptor D2
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
ELMOD1 ELMO/CED-12 domain containing 1
EPS8 epidermal growth factor receptor pathway substrate 8
FABP3 fatty acid binding protein 3, muscle and heart
FAM3D family with sequence similarity 3, member D
FFAR4 free fatty acid receptor 4
FGFBP1 fibroblast growth factor binding protein 1
FH fumarate hydratase
FOXO3 forkhead box O3
GAB1 GRB2-associated binding protein 1
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GALR3 galanin receptor 3
GAS2 growth arrest-specific 2
GDF7 growth differentiation factor 7
GDNF glial cell derived neurotrophic factor
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GPR156 G protein-coupled receptor 156
GPR176 G protein-coupled receptor 176
GPR6 G protein-coupled receptor 6
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
GRK5 G protein-coupled receptor kinase 5
GTF2H1 general transcription factor IIH, polypeptide 1, 62kDa
HACD2 3-hydroxyacyl-CoA dehydratase 2
HCRT hypocretin (orexin) neuropeptide precursor
HIPK3 homeodomain interacting protein kinase 3
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-DRB5 major histocompatibility complex, class II, DR beta 5
HSD17B12 hydroxysteroid (17-beta) dehydrogenase 12
HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
ICOSLG inducible T-cell co-stimulator ligand
IFNA21 interferon, alpha 21
IFNGR1 interferon gamma receptor 1
IFNW1 interferon, omega 1
IGFBP3 insulin-like growth factor binding protein 3
IK IK cytokine, down-regulator of HLA II
IL1A interleukin 1, alpha
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KNTC1 kinetochore associated 1
LDHA lactate dehydrogenase A
LUC7L3 LUC7-like 3 (S. cerevisiae)
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MCL1 myeloid cell leukemia 1
MDM4 MDM4, p53 regulator
MEFV Mediterranean fever
MPO myeloperoxidase
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
MVK mevalonate kinase
MYH10 myosin, heavy chain 10, non-muscle
NEK6 NIMA-related kinase 6
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NLGN1 neuroligin 1
NR4A1 nuclear receptor subfamily 4, group A, member 1
OR10K1 olfactory receptor, family 10, subfamily K, member 1
OR10T2 olfactory receptor, family 10, subfamily T, member 2
OR10Z1 olfactory receptor, family 10, subfamily Z, member 1
OR2S2 olfactory receptor, family 2, subfamily S, member 2 (gene/pseudogene)
OR52B4 olfactory receptor, family 52, subfamily B, member 4 (gene/pseudogene)
OR52D1 olfactory receptor, family 52, subfamily D, member 1
OR52E6 olfactory receptor, family 52, subfamily E, member 6
OR6C1 olfactory receptor, family 6, subfamily C, member 1
OR8S1 olfactory receptor, family 8, subfamily S, member 1
ORC5 origin recognition complex, subunit 5
OXA1L oxidase (cytochrome c) assembly 1-like
P2RY11 purinergic receptor P2Y, G-protein coupled, 11
PARD3B par-3 family cell polarity regulator beta
PAX7 paired box 7
PCLO piccolo presynaptic cytomatrix protein
PCSK9 proprotein convertase subtilisin/kexin type 9
PDCD10 programmed cell death 10
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PLCB2 phospholipase C, beta 2
PLCE1 phospholipase C, epsilon 1
PLCXD2 phosphatidylinositol-specific phospholipase C, X domain containing 2
POLE polymerase (DNA directed), epsilon, catalytic subunit
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PRKCE protein kinase C, epsilon
PRKCH protein kinase C, eta
PRKCQ protein kinase C, theta
PRKD1 protein kinase D1
PSEN1 presenilin 1
PSEN2 presenilin 2
PTEN phosphatase and tensin homolog
PTTG1 pituitary tumor-transforming 1
RAD1 RAD1 checkpoint DNA exonuclease
RFFL ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
RFWD2 ring finger and WD repeat domain 2, E3 ubiquitin protein ligase
RIF1 replication timing regulatory factor 1
RUNX3 runt-related transcription factor 3
S100A2 S100 calcium binding protein A2
SCARB1 scavenger receptor class B, member 1
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SCP2 sterol carrier protein 2
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2
SNAP25 synaptosomal-associated protein, 25kDa
SORCS1 sortilin-related VPS10 domain containing receptor 1
SP100 SP100 nuclear antigen
SPRED2 sprouty-related, EVH1 domain containing 2
SRA1 steroid receptor RNA activator 1
STAP2 signal transducing adaptor family member 2
STK17A serine/threonine kinase 17a
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit
SULF1 sulfatase 1
SYN3 synapsin III
TBX5 T-box 5
TBXAS1 thromboxane A synthase 1 (platelet)
TDP2 tyrosyl-DNA phosphodiesterase 2
TEC tec protein tyrosine kinase
THRB thyroid hormone receptor, beta
TLR5 toll-like receptor 5
TMEM189-UBE2V1 TMEM189-UBE2V1 readthrough
TNF tumor necrosis factor
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TP53RK TP53 regulating kinase
TPI1P2 triosephosphate isomerase 1 pseudogene 2
TRA T cell receptor alpha locus
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRAJ10 T cell receptor alpha joining 10
TRIM69 tripartite motif containing 69
TRPC3 transient receptor potential cation channel, subfamily C, member 3
TRPS1 trichorhinophalangeal syndrome I
TUBB tubulin, beta class I
TVP23CP2 TVP23C pseudogene 2
UQCRC2 ubiquinol-cytochrome c reductase core protein II
VDAC1 voltage-dependent anion channel 1
VEGFA vascular endothelial growth factor A
WDR37 WD repeat domain 37
WISP1 WNT1 inducible signaling pathway protein 1