naringenin-4422 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the naringenin-4422 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
AAMDC adipogenesis associated, Mth938 domain containing
ACPP acid phosphatase, prostate
ADAMTSL3 ADAMTS-like 3
AGER advanced glycosylation end product-specific receptor
ALS2CL ALS2 C-terminal like
ATXN7L1 ataxin 7-like 1
BCAM basal cell adhesion molecule (Lutheran blood group)
BCAT2 branched chain amino-acid transaminase 2, mitochondrial
BCL2 B-cell CLL/lymphoma 2
BMP8B bone morphogenetic protein 8b
BRS3 bombesin-like receptor 3
C1QB complement component 1, q subcomponent, B chain
C22ORF46 chromosome 22 open reading frame 46
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CASP2 caspase 2, apoptosis-related cysteine peptidase
CDC14B cell division cycle 14B
CEP135 centrosomal protein 135kDa
COL8A2 collagen, type VIII, alpha 2
COLGALT2 collagen beta(1-O)galactosyltransferase 2
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa
CTNS cystinosin, lysosomal cystine transporter
DFNB31 deafness, autosomal recessive 31
DIO2 deiodinase, iodothyronine, type II
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DPF1 D4, zinc and double PHD fingers family 1
E2F5 E2F transcription factor 5, p130-binding
EDNRA endothelin receptor type A
EGR3 early growth response 3
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
FADS2 fatty acid desaturase 2
FAM169A family with sequence similarity 169, member A
FAM46C family with sequence similarity 46, member C
FRMD1 FERM domain containing 1
FXYD5 FXYD domain containing ion transport regulator 5
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GOSR1 golgi SNAP receptor complex member 1
GPATCH2L G patch domain containing 2-like
GRIP2 glutamate receptor interacting protein 2
GRM1 glutamate receptor, metabotropic 1
HEXIM1 hexamethylene bis-acetamide inducible 1
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IL11RA interleukin 11 receptor, alpha
IL2RB interleukin 2 receptor, beta
JAK2 Janus kinase 2
KCNK5 potassium channel, two pore domain subfamily K, member 5
KIAA0040 KIAA0040
KIAA1024 KIAA1024
KIAA1324 KIAA1324
KRT16 keratin 16, type I
KRT9 keratin 9, type I
LAT2 linker for activation of T cells family, member 2
LINC00260 long intergenic non-protein coding RNA 260
LY86 lymphocyte antigen 86
MAGEA5 melanoma antigen family A5
MALL mal, T-cell differentiation protein-like
MEF2C myocyte enhancer factor 2C
MMP19 matrix metallopeptidase 19
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NDRG2 NDRG family member 2
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NOX1 NADPH oxidase 1
NPY1R neuropeptide Y receptor Y1
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
ORAI2 ORAI calcium release-activated calcium modulator 2
PART1 prostate androgen-regulated transcript 1 (non-protein coding)
PCDHGA8 protocadherin gamma subfamily A, 8
PDLIM3 PDZ and LIM domain 3
PLEKHH3 pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PSAT1 phosphoserine aminotransferase 1
PTHLH parathyroid hormone-like hormone
RAB6A RAB6A, member RAS oncogene family
RAB6B RAB6B, member RAS oncogene family
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RARA retinoic acid receptor, alpha
RASL11B RAS-like, family 11, member B
RBP4 retinol binding protein 4, plasma
RGCC regulator of cell cycle
RPS28 ribosomal protein S28
S100A7 S100 calcium binding protein A7
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SLC48A1 solute carrier family 48 (heme transporter), member 1
SPON2 spondin 2, extracellular matrix protein
SYK spleen tyrosine kinase
TBRG4 transforming growth factor beta regulator 4
TBX6 T-box 6
TCF12 transcription factor 12
THTPA thiamine triphosphatase
TRIL TLR4 interactor with leucine-rich repeats
TTLL3 tubulin tyrosine ligase-like family member 3
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
XYLB xylulokinase homolog (H. influenzae)
ZNF236 zinc finger protein 236
ZNF639 zinc finger protein 639

decreased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ADAM2 ADAM metallopeptidase domain 2
AMT aminomethyltransferase
ANXA2P3 annexin A2 pseudogene 3
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
ARPIN actin-related protein 2/3 complex inhibitor
ATP10D ATPase, class V, type 10D
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BTF3P11 basic transcription factor 3 pseudogene 11
BTF3P12 basic transcription factor 3 pseudogene 12
C11ORF63 chromosome 11 open reading frame 63
C1QTNF3 C1q and tumor necrosis factor related protein 3
CAMK1 calcium/calmodulin-dependent protein kinase I
CAMK1D calcium/calmodulin-dependent protein kinase ID
CCDC64 coiled-coil domain containing 64
CCL16 chemokine (C-C motif) ligand 16
CD82 CD82 molecule
CDHR2 cadherin-related family member 2
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CFAP45 cilia and flagella associated protein 45
CPNE7 copine VII
CSF1R colony stimulating factor 1 receptor
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
ELSPBP1 epididymal sperm binding protein 1
ERN2 endoplasmic reticulum to nucleus signaling 2
EVA1B eva-1 homolog B (C. elegans)
FAM110B family with sequence similarity 110, member B
FAM188A family with sequence similarity 188, member A
FBXL7 F-box and leucine-rich repeat protein 7
FLJ11710 uncharacterized protein FLJ11710
FLJ21369 uncharacterized protein FLJ21369
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GADD45G growth arrest and DNA-damage-inducible, gamma
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GRB7 growth factor receptor-bound protein 7
GREB1L growth regulation by estrogen in breast cancer-like
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HIRA histone cell cycle regulator
HIST1H1D histone cluster 1, H1d
HIST1H3E histone cluster 1, H3e
HOXB2 homeobox B2
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IL12RB1 interleukin 12 receptor, beta 1
IL2 interleukin 2
JPH3 junctophilin 3
KLF7 Kruppel-like factor 7 (ubiquitous)
KPNA5 karyopherin alpha 5 (importin alpha 6)
KRT83 keratin 83, type II
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LY6G6C lymphocyte antigen 6 complex, locus G6C
MAST3 microtubule associated serine/threonine kinase 3
MCTP1 multiple C2 domains, transmembrane 1
MEGF6 multiple EGF-like-domains 6
MFGE8 milk fat globule-EGF factor 8 protein
MGC2889 uncharacterized protein MGC2889
MLLT4-AS1 MLLT4 antisense RNA 1 (head to head)
MMP3 matrix metallopeptidase 3
MUC6 mucin 6, oligomeric mucus/gel-forming
MX2 MX dynamin-like GTPase 2
NAT6 N-acetyltransferase 6 (GCN5-related)
NEUROD1 neuronal differentiation 1
NIPSNAP3B nipsnap homolog 3B (C. elegans)
NKX2-5 NK2 homeobox 5
NPTX1 neuronal pentraxin I
NPY4R neuropeptide Y receptor Y4
NYNRIN NYN domain and retroviral integrase containing
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OR1D2 olfactory receptor, family 1, subfamily D, member 2
PCDHB12 protocadherin beta 12
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PGPEP1 pyroglutamyl-peptidase I
PHOX2A paired-like homeobox 2a
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLEKHA6 pleckstrin homology domain containing, family A member 6
POU4F2 POU class 4 homeobox 2
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PTPRS protein tyrosine phosphatase, receptor type, S
RAB3A RAB3A, member RAS oncogene family
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RNF126P1 ring finger protein 126 pseudogene 1
RNF43 ring finger protein 43
RORC RAR-related orphan receptor C
RPL10L ribosomal protein L10-like
RUSC2 RUN and SH3 domain containing 2
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SPTBN5 spectrin, beta, non-erythrocytic 5
TBL1Y transducin (beta)-like 1, Y-linked
THBS3 thrombospondin 3
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TNNI3 troponin I type 3 (cardiac)
TPSG1 tryptase gamma 1
VIM vimentin
WDR33 WD repeat domain 33
WNT10B wingless-type MMTV integration site family, member 10B
ZBTB44 zinc finger and BTB domain containing 44