naringin-2425 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the naringin-2425 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACRV1 acrosomal vesicle protein 1
ADAMDEC1 ADAM-like, decysin 1
AMACR alpha-methylacyl-CoA racemase
BMP7 bone morphogenetic protein 7
C1ORF105 chromosome 1 open reading frame 105
C6ORF10 chromosome 6 open reading frame 10
CA1 carbonic anhydrase I
CALML3 calmodulin-like 3
CCDC85C coiled-coil domain containing 85C
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDHR1 cadherin-related family member 1
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
CLIC5 chloride intracellular channel 5
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
COL9A3 collagen, type IX, alpha 3
CROT carnitine O-octanoyltransferase
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
DCN decorin
DCX doublecortin
DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58
DNAH3 dynein, axonemal, heavy chain 3
DNAI2 dynein, axonemal, intermediate chain 2
EML2 echinoderm microtubule associated protein like 2
FAM182B family with sequence similarity 182, member B
FLT1 fms-related tyrosine kinase 1
FOXE1 forkhead box E1
GIPR gastric inhibitory polypeptide receptor
GLP1R glucagon-like peptide 1 receptor
GRPR gastrin-releasing peptide receptor
GYPB glycophorin B (MNS blood group)
HIST1H2BC histone cluster 1, H2bc
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
IGFBP5 insulin-like growth factor binding protein 5
ISG20 interferon stimulated exonuclease gene 20kDa
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
LARGE like-glycosyltransferase
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MAP1A microtubule-associated protein 1A
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MAPT microtubule-associated protein tau
MFAP3 microfibrillar-associated protein 3
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MMP26 matrix metallopeptidase 26
MNMIP1 manchette microtubule inner protein 1
MRC2 mannose receptor, C type 2
MRPL41 mitochondrial ribosomal protein L41
MRPS12 mitochondrial ribosomal protein S12
MUC4 mucin 4, cell surface associated
MYH14 myosin, heavy chain 14, non-muscle
NEBL nebulette
NEK11 NIMA-related kinase 11
NTF3 neurotrophin 3
OR10H1 olfactory receptor, family 10, subfamily H, member 1
OR1D2 olfactory receptor, family 1, subfamily D, member 2
PDE4C phosphodiesterase 4C, cAMP-specific
PDE4DIP phosphodiesterase 4D interacting protein
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
PLA2G5 phospholipase A2, group V
PLSCR4 phospholipid scramblase 4
PQLC2 PQ loop repeat containing 2
PRDX2 peroxiredoxin 2
PTGDS prostaglandin D2 synthase 21kDa (brain)
RAB13 RAB13, member RAS oncogene family
RAB26 RAB26, member RAS oncogene family
RAB27B RAB27B, member RAS oncogene family
RAB40A RAB40A, member RAS oncogene family
RASAL2 RAS protein activator like 2
RPL13 ribosomal protein L13
RUFY3 RUN and FYVE domain containing 3
SERHL2 serine hydrolase-like 2
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SIGLEC8 sialic acid binding Ig-like lectin 8
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter)
SMCP sperm mitochondria-associated cysteine-rich protein
SPACA1 sperm acrosome associated 1
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
SYCE1L synaptonemal complex central element protein 1-like
SYT13 synaptotagmin XIII
TAS2R1 taste receptor, type 2, member 1
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TK2 thymidine kinase 2, mitochondrial
TLL2 tolloid-like 2
TLR8 toll-like receptor 8
TOX thymocyte selection-associated high mobility group box
TTC12 tetratricopeptide repeat domain 12
UBXN1 UBX domain protein 1
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
UPK2 uroplakin 2
USP6NL USP6 N-terminal like
VCX2 variable charge, X-linked 2
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF695 zinc finger protein 695

decreased expression

Symbol Name
AHCTF1 AT hook containing transcription factor 1
AIDA axin interactor, dorsalization associated
ANKRD40 ankyrin repeat domain 40
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
APOC2 apolipoprotein C-II
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ATAD2 ATPase family, AAA domain containing 2
AXIN1 axin 1
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BAK1 BCL2-antagonist/killer 1
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C10ORF88 chromosome 10 open reading frame 88
C5 complement component 5
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CHEK2 checkpoint kinase 2
CHIC2 cysteine-rich hydrophobic domain 2
CHMP1A charged multivesicular body protein 1A
CLK1 CDC-like kinase 1
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
DEPDC5 DEP domain containing 5
DHRS7B dehydrogenase/reductase (SDR family) member 7B
DIXDC1 DIX domain containing 1
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2
DNAL4 dynein, axonemal, light chain 4
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
ECI1 enoyl-CoA delta isomerase 1
EMILIN2 elastin microfibril interfacer 2
FEM1C fem-1 homolog c (C. elegans)
FKBP9 FK506 binding protein 9, 63 kDa
GLTP glycolipid transfer protein
GMEB1 glucocorticoid modulatory element binding protein 1
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPBP1L1 GC-rich promoter binding protein 1-like 1
GSTCD glutathione S-transferase, C-terminal domain containing
GTF2I general transcription factor IIi
HCFC2 host cell factor C2
HHLA3 HERV-H LTR-associating 3
HLA-J major histocompatibility complex, class I, J (pseudogene)
IFT46 intraflagellar transport 46
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
KIAA0232 KIAA0232
KIAA0753 KIAA0753
KPNA4 karyopherin alpha 4 (importin alpha 3)
LAMP5 lysosomal-associated membrane protein family, member 5
LAX1 lymphocyte transmembrane adaptor 1
LIG4 ligase IV, DNA, ATP-dependent
LRRC20 leucine rich repeat containing 20
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAPK3 mitogen-activated protein kinase 3
MICALL2 MICAL-like 2
MOCS2 molybdenum cofactor synthesis 2
NARFL nuclear prelamin A recognition factor-like
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NLK nemo-like kinase
NMD3 NMD3 ribosome export adaptor
NPIPB3 nuclear pore complex interacting protein family, member B3
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9
ORC2 origin recognition complex, subunit 2
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4
PCYOX1 prenylcysteine oxidase 1
PLA2G15 phospholipase A2, group XV
PLAG1 pleiomorphic adenoma gene 1
PNRC1 proline-rich nuclear receptor coactivator 1
POMZP3 POM121 and ZP3 fusion
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PSAT1 phosphoserine aminotransferase 1
RC3H2 ring finger and CCCH-type domains 2
RINT1 RAD50 interactor 1
RNF121 ring finger protein 121
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
SAMD9 sterile alpha motif domain containing 9
SCYL2 SCY1-like 2 (S. cerevisiae)
SERPINB10 serpin peptidase inhibitor, clade B (ovalbumin), member 10
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SETD8 SET domain containing (lysine methyltransferase) 8
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC25A40 solute carrier family 25, member 40
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5
SLC35A5 solute carrier family 35, member A5
SNX16 sorting nexin 16
SSFA2 sperm specific antigen 2
STK16 serine/threonine kinase 16
SYNJ2BP synaptojanin 2 binding protein
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TGM5 transglutaminase 5
TMEM156 transmembrane protein 156
TSR2 TSR2, 20S rRNA accumulation, homolog (S. cerevisiae)
USP8 ubiquitin specific peptidase 8
YKT6 YKT6 v-SNARE homolog (S. cerevisiae)
ZBED8 zinc finger, BED-type containing 8
ZFYVE21 zinc finger, FYVE domain containing 21
ZNF197 zinc finger protein 197
ZNF215 zinc finger protein 215
ZNF253 zinc finger protein 253
ZW10 zw10 kinetochore protein