naringin-5666 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the naringin-5666 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
ADAM12 ADAM metallopeptidase domain 12
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
APOC1 apolipoprotein C-I
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ATAD5 ATPase family, AAA domain containing 5
ATHL1 ATH1, acid trehalase-like 1 (yeast)
BDKRB1 bradykinin receptor B1
BEX1 brain expressed, X-linked 1
C1QB complement component 1, q subcomponent, B chain
CD58 CD58 molecule
CDKN2A cyclin-dependent kinase inhibitor 2A
CNOT4 CCR4-NOT transcription complex, subunit 4
CREB5 cAMP responsive element binding protein 5
CRHR2 corticotropin releasing hormone receptor 2
CSTA cystatin A (stefin A)
DGCR8 DGCR8 microprocessor complex subunit
DLC1 DLC1 Rho GTPase activating protein
DRD2 dopamine receptor D2
EGFR epidermal growth factor receptor
ERAP1 endoplasmic reticulum aminopeptidase 1
FAM46C family with sequence similarity 46, member C
FBXL18 F-box and leucine-rich repeat protein 18
FGF1 fibroblast growth factor 1 (acidic)
FGFR1 fibroblast growth factor receptor 1
FHL1 four and a half LIM domains 1
FOXN3 forkhead box N3
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GLDC glycine dehydrogenase (decarboxylating)
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GPM6B glycoprotein M6B
GRM6 glutamate receptor, metabotropic 6
GSAP gamma-secretase activating protein
HCRTR2 hypocretin (orexin) receptor 2
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HOXD9 homeobox D9
IL17RA interleukin 17 receptor A
ING2 inhibitor of growth family, member 2
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8
KCTD12 potassium channel tetramerization domain containing 12
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
KIAA0040 KIAA0040
KIAA0355 KIAA0355
KLF1 Kruppel-like factor 1 (erythroid)
LDHB lactate dehydrogenase B
LEPR leptin receptor
LIN7A lin-7 homolog A (C. elegans)
LINC00341 long intergenic non-protein coding RNA 341
LMO4 LIM domain only 4
LPCAT4 lysophosphatidylcholine acyltransferase 4
LRP12 low density lipoprotein receptor-related protein 12
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
MLANA melan-A
MMP27 matrix metallopeptidase 27
MTMR8 myotubularin related protein 8
MTRF1L mitochondrial translational release factor 1-like
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
NDRG2 NDRG family member 2
NEFL neurofilament, light polypeptide
NEU3 sialidase 3 (membrane sialidase)
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NOD1 nucleotide-binding oligomerization domain containing 1
NPAS2 neuronal PAS domain protein 2
NPR3 natriuretic peptide receptor 3
NPTX1 neuronal pentraxin I
OASL 2'-5'-oligoadenylate synthetase-like
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PCSK6 proprotein convertase subtilisin/kexin type 6
PDCD6 programmed cell death 6
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PSAT1 phosphoserine aminotransferase 1
RAB2A RAB2A, member RAS oncogene family
RARA retinoic acid receptor, alpha
RREB1 ras responsive element binding protein 1
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC14A2 solute carrier family 14 (urea transporter), member 2
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SPN sialophorin
SYNGR1 synaptogyrin 1
SYT12 synaptotagmin XII
TAS2R1 taste receptor, type 2, member 1
TFF2 trefoil factor 2
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TP63 tumor protein p63
TRD T cell receptor delta locus
TSPAN7 tetraspanin 7
VIM vimentin
WBP5 WW domain binding protein 5
WFDC2 WAP four-disulfide core domain 2
XIST X inactive specific transcript (non-protein coding)
ZNF137P zinc finger protein 137, pseudogene
ZNF419 zinc finger protein 419
ZNF589 zinc finger protein 589
ZNF711 zinc finger protein 711

decreased expression

Symbol Name
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
C19ORF40 chromosome 19 open reading frame 40
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C6ORF47 chromosome 6 open reading frame 47
CASS4 Cas scaffolding protein family member 4
CBX8 chromobox homolog 8
CCDC121 coiled-coil domain containing 121
CCP110 centriolar coiled coil protein 110kDa
CD82 CD82 molecule
CFD complement factor D (adipsin)
CIDEC cell death-inducing DFFA-like effector c
CLGN calmegin
CLIP4 CAP-GLY domain containing linker protein family, member 4
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CRIP1 cysteine-rich protein 1 (intestinal)
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DGAT1 diacylglycerol O-acyltransferase 1
DGKE diacylglycerol kinase, epsilon 64kDa
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
ERCC6 excision repair cross-complementation group 6
FAM169A family with sequence similarity 169, member A
FKBP5 FK506 binding protein 5
FUZ fuzzy planar cell polarity protein
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GPR27 G protein-coupled receptor 27
GSTM2 glutathione S-transferase mu 2 (muscle)
HIST1H2BO histone cluster 1, H2bo
HIST1H3B histone cluster 1, H3b
HMHA1 histocompatibility (minor) HA-1
HOXD11 homeobox D11
HSPA2 heat shock 70kDa protein 2
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFT54 intraflagellar transport 54
INO80D INO80 complex subunit D
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
JMJD4 jumonji domain containing 4
LAX1 lymphocyte transmembrane adaptor 1
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LMBR1L limb development membrane protein 1-like
LPXN leupaxin
LRP5L low density lipoprotein receptor-related protein 5-like
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
MYL5 myosin, light chain 5, regulatory
N4BP3 NEDD4 binding protein 3
NT5DC3 5'-nucleotidase domain containing 3
NXPE3 neurexophilin and PC-esterase domain family, member 3
OCA2 oculocutaneous albinism II
PACS1 phosphofurin acidic cluster sorting protein 1
PADI1 peptidyl arginine deiminase, type I
PARP12 poly (ADP-ribose) polymerase family, member 12
PCDHB3 protocadherin beta 3
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PGR progesterone receptor
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
POLL polymerase (DNA directed), lambda
PYCRL pyrroline-5-carboxylate reductase-like
QPCT glutaminyl-peptide cyclotransferase
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RCAN3 RCAN family member 3
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RNF39 ring finger protein 39
RPGRIP1L RPGRIP1-like
RPL13P5 ribosomal protein L13 pseudogene 5
S100A4 S100 calcium binding protein A4
S100A9 S100 calcium binding protein A9
SCGB2A2 secretoglobin, family 2A, member 2
SDC3 syndecan 3
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SLMO1 slowmo homolog 1 (Drosophila)
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SP1 Sp1 transcription factor
STAG3 stromal antigen 3
STARD5 StAR-related lipid transfer (START) domain containing 5
TBR1 T-box, brain, 1
TDRD12 tudor domain containing 12
TET3 tet methylcytosine dioxygenase 3
TREM1 triggering receptor expressed on myeloid cells 1
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TUBGCP5 tubulin, gamma complex associated protein 5
UNC119 unc-119 homolog (C. elegans)
USP20 ubiquitin specific peptidase 20
WDR25 WD repeat domain 25
WDR33 WD repeat domain 33
ZNF141 zinc finger protein 141
ZNF286A zinc finger protein 286A
ZNF480 zinc finger protein 480
ZNF506 zinc finger protein 506
ZNF516 zinc finger protein 516
ZNF668 zinc finger protein 668
ZNF74 zinc finger protein 74
ZNF750 zinc finger protein 750
ZNHIT2 zinc finger, HIT-type containing 2