nasopharynx carcinoma Gene Set

Dataset GWASdb SNP-Disease Associations
Category disease or phenotype associations
Type disease
Description A pharynx cancer that is located_in the nasopharynx, the uppermost region of the pharynx or throat, where the nasal passages and auditory tubes join the remainder of the upper respiratory tract. (Human Disease Ontology, DOID_9261)
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/DOID:9261
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Genes

84 genes associated with the disease nasopharynx carcinoma in GWAS and other genetic association datasets from the GWASdb SNP-Disease Associations dataset.

Symbol Name Standardized Value
FGFR2 fibroblast growth factor receptor 2 2.84786
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal) 2.56622
KITLG KIT ligand 2.2982
MSMB microseminoprotein, beta- 2.24069
SMAD7 SMAD family member 7 2.21691
CDK10 cyclin-dependent kinase 10 2.20043
HYKK hydroxylysine kinase 2.17705
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 2.12532
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 2.1154
ITGA6 integrin, alpha 6 2.08561
IRF4 interferon regulatory factor 4 2.01898
IKZF1 IKAROS family zinc finger 1 (Ikaros) 1.98999
ARID5B AT rich interactive domain 5B (MRF1-like) 1.96389
HNF1B HNF1 homeobox B 1.93944
BARD1 BRCA1 associated RING domain 1 1.92026
TERT telomerase reverse transcriptase 1.90896
PIGU phosphatidylinositol glycan anchor biosynthesis, class U 1.83309
PDLIM5 PDZ and LIM domain 5 1.80795
CDKN2B-AS1 CDKN2B antisense RNA 1 1.79589
CASC15 cancer susceptibility candidate 15 (non-protein coding) 1.79076
TYR tyrosinase 1.77455
BAK1 BCL2-antagonist/killer 1 1.74
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1 1.69126
RTEL1 regulator of telomere elongation helicase 1 1.67004
PADI6 peptidyl arginine deiminase, type VI 1.6622
APOM apolipoprotein M 1.65612
ZNRD1-AS1 ZNRD1 antisense RNA 1 1.60057
CLPTM1L CLPTM1-like 1.55738
ACOXL acyl-CoA oxidase-like 1.55738
PSCA prostate stem cell antigen 1.55738
NR5A2 nuclear receptor subfamily 5, group A, member 2 1.55738
EEFSEC eukaryotic elongation factor, selenocysteine-tRNA-specific 1.54533
SLC22A3 solute carrier family 22 (organic cation transporter), member 3 1.52524
SP140 SP140 nuclear body protein 1.52524
COLCA2 colorectal cancer associated 2 1.52524
EMBP1 embigin pseudogene 1 1.52067
LMTK2 lemur tyrosine kinase 2 1.50906
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent) 1.48714
FARP2 FERM, RhoGEF and pleckstrin domain protein 2 1.48714
TNFRSF19 tumor necrosis factor receptor superfamily, member 19 1.48714
LSP1 lymphocyte-specific protein 1 1.47287
PRKD2 protein kinase D2 1.46277
RHPN2 rhophilin, Rho GTPase binding protein 2 1.45471
EHBP1 EH domain binding protein 1 1.43537
PHLDB1 pleckstrin homology-like domain, family B, member 1 1.42467
MECOM MDS1 and EVI1 complex locus 1.42467
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.42467
THADA thyroid adenoma associated 1.39396
RNF146 ring finger protein 146 1.37327
ITGA9 integrin, alpha 9 1.33186
MAP1LC3B2 microtubule-associated protein 1 light chain 3 beta 2 1.32598
COL1A1 collagen, type I, alpha 1 1.32598
CTBP2 C-terminal binding protein 2 1.28906
RAD51B RAD51 paralog B 1.28906
MT1A metallothionein 1A 1.28734
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon 1.26953
ZNF230 zinc finger protein 230 1.25477
MTAP methylthioadenosine phosphorylase 1.25477
TNRC6B trinucleotide repeat containing 6B 1.24194
TGM5 transglutaminase 5 1.19386
ACTA2 actin, alpha 2, smooth muscle, aorta 1.19386
LINC00299 long intergenic non-protein coding RNA 299 1.16953
TSSC1 tumor suppressing subtransferable candidate 1 1.15334
JAZF1 JAZF zinc finger 1 1.14463
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like 1.14463
UCK2 uridine-cytidine kinase 2 1.14463
RYR2 ryanodine receptor 2 (cardiac) 1.14463
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 1.14463
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive) 1.10764
RBMS3 RNA binding motif, single stranded interacting protein 3 1.10764
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 1.10764
HAPLN1 hyaluronan and proteoglycan link protein 1 1.10764
CPEB1 cytoplasmic polyadenylation element binding protein 1 1.07599
ST6GALNAC3 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 1.07599
SDCCAG8 serologically defined colon cancer antigen 8 1.05056
KCNMB2 potassium channel subfamily M regulatory beta subunit 2 1.02476
FBN1 fibrillin 1 1.02476
GRIK1 glutamate receptor, ionotropic, kainate 1 1.02476
SPATA22 spermatogenesis associated 22 0.989039
IL1RAP interleukin 1 receptor accessory protein 0.986376
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 0.971169
PARD3 par-3 family cell polarity regulator 0.971169
CEMIP cell migration inducing protein, hyaluronan binding 0.804621
HLA-F major histocompatibility complex, class I, F 0.794247