natamycin-5809 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the natamycin-5809 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AASS aminoadipate-semialdehyde synthase
ACE angiotensin I converting enzyme
ACVR1B activin A receptor, type IB
AKR1C1 aldo-keto reductase family 1, member C1
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARMC6 armadillo repeat containing 6
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BCR breakpoint cluster region
C11ORF1 chromosome 11 open reading frame 1
C7ORF69 chromosome 7 open reading frame 69
CASP1 caspase 1, apoptosis-related cysteine peptidase
CCL27 chemokine (C-C motif) ligand 27
CCNT1 cyclin T1
CCPG1 cell cycle progression 1
CD70 CD70 molecule
CDON cell adhesion associated, oncogene regulated
CEP250 centrosomal protein 250kDa
CFLAR CASP8 and FADD-like apoptosis regulator
CRYBB2P1 crystallin, beta B2 pseudogene 1
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CTSF cathepsin F
DENND3 DENN/MADD domain containing 3
E2F4 E2F transcription factor 4, p107/p130-binding
EHBP1L1 EH domain binding protein 1-like 1
EPHB2 EPH receptor B2
FABP3 fatty acid binding protein 3, muscle and heart
FAM50B family with sequence similarity 50, member B
FCGRT Fc fragment of IgG, receptor, transporter, alpha
FLOT1 flotillin 1
FLT4 fms-related tyrosine kinase 4
GDAP1 ganglioside induced differentiation associated protein 1
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GPR137 G protein-coupled receptor 137
GPR176 G protein-coupled receptor 176
H2AFJ H2A histone family, member J
HIST1H3A histone cluster 1, H3a
HOXA4 homeobox A4
IGHM immunoglobulin heavy constant mu
IGL immunoglobulin lambda locus
IL16 interleukin 16
IL4R interleukin 4 receptor
IL5RA interleukin 5 receptor, alpha
IRAK4 interleukin-1 receptor-associated kinase 4
KITLG KIT ligand
KSR1 kinase suppressor of ras 1
LAMC3 laminin, gamma 3
LEFTY2 left-right determination factor 2
MAN2A2 mannosidase, alpha, class 2A, member 2
METTL16 methyltransferase like 16
MXD4 MAX dimerization protein 4
MYH14 myosin, heavy chain 14, non-muscle
NBEAL2 neurobeachin-like 2
NEK1 NIMA-related kinase 1
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
ONECUT2 one cut homeobox 2
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PACRG PARK2 co-regulated
PEX16 peroxisomal biogenesis factor 16
PHF7 PHD finger protein 7
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PPP4R4 protein phosphatase 4, regulatory subunit 4
PRB1 proline-rich protein BstNI subfamily 1
PRF1 perforin 1 (pore forming protein)
PRPF18 pre-mRNA processing factor 18
RAB11FIP3 RAB11 family interacting protein 3 (class II)
RAB2A RAB2A, member RAS oncogene family
RARG retinoic acid receptor, gamma
RGS12 regulator of G-protein signaling 12
SAMD4A sterile alpha motif domain containing 4A
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SETD8 SET domain containing (lysine methyltransferase) 8
SHANK2 SH3 and multiple ankyrin repeat domains 2
SIPA1L3 signal-induced proliferation-associated 1 like 3
SIRPB1 signal-regulatory protein beta 1
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SMYD2 SET and MYND domain containing 2
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SPHK2 sphingosine kinase 2
STS steroid sulfatase (microsomal), isozyme S
STX7 syntaxin 7
SYMPK symplekin
SYT11 synaptotagmin XI
TBL1Y transducin (beta)-like 1, Y-linked
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMCC1 transmembrane and coiled-coil domain family 1
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TPMT thiopurine S-methyltransferase
TSKU tsukushi, small leucine rich proteoglycan
TTC38 tetratricopeptide repeat domain 38
UROD uroporphyrinogen decarboxylase
WWP2 WW domain containing E3 ubiquitin protein ligase 2
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
ZC3H7B zinc finger CCCH-type containing 7B
ZNF236 zinc finger protein 236
ZNF606 zinc finger protein 606
ZXDB zinc finger, X-linked, duplicated B

decreased expression

Symbol Name
AMPD2 adenosine monophosphate deaminase 2
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2
ASAP1-IT1 ASAP1 intronic transcript 1
AZI2 5-azacytidine induced 2
C10ORF88 chromosome 10 open reading frame 88
C11ORF63 chromosome 11 open reading frame 63
C17ORF85 chromosome 17 open reading frame 85
C2ORF68 chromosome 2 open reading frame 68
CARD8 caspase recruitment domain family, member 8
CBX7 chromobox homolog 7
CCP110 centriolar coiled coil protein 110kDa
CEP131 centrosomal protein 131kDa
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CTSD cathepsin D
CTSK cathepsin K
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
DDIT3 DNA-damage-inducible transcript 3
DNAL4 dynein, axonemal, light chain 4
DOLPP1 dolichyldiphosphatase 1
EDC3 enhancer of mRNA decapping 3
ELOVL4 ELOVL fatty acid elongase 4
EMC6 ER membrane protein complex subunit 6
EPPK1 epiplakin 1
ERCC2 excision repair cross-complementation group 2
ERN2 endoplasmic reticulum to nucleus signaling 2
F8 coagulation factor VIII, procoagulant component
FAM127B family with sequence similarity 127, member B
FAM155A family with sequence similarity 155, member A
FAM222B family with sequence similarity 222, member B
FHOD1 formin homology 2 domain containing 1
FOXA1 forkhead box A1
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene)
GTPBP2 GTP binding protein 2
HAUS7 HAUS augmin-like complex, subunit 7
HIST1H1T histone cluster 1, H1t
HIST1H2AI histone cluster 1, H2ai
HIST1H2AJ histone cluster 1, H2aj
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
HYMAI hydatidiform mole associated and imprinted (non-protein coding)
KIAA0556 KIAA0556
KRT15 keratin 15, type I
LRRC16A leucine rich repeat containing 16A
LRRC20 leucine rich repeat containing 20
LRRC42 leucine rich repeat containing 42
LZTR1 leucine-zipper-like transcription regulator 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MANSC1 MANSC domain containing 1
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAP6D1 MAP6 domain containing 1
MBTD1 mbt domain containing 1
MCM9 minichromosome maintenance complex component 9
MGAT4B mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B
MGC12488
MYBBP1A MYB binding protein (P160) 1a
NCS1 neuronal calcium sensor 1
NDE1 nudE neurodevelopment protein 1
NME6 NME/NM23 nucleoside diphosphate kinase 6
NPM3 nucleophosmin/nucleoplasmin 3
NPR3 natriuretic peptide receptor 3
NRSN2 neurensin 2
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
ORC2 origin recognition complex, subunit 2
PAN2 PAN2 poly(A) specific ribonuclease subunit
PDE12 phosphodiesterase 12
PDHX pyruvate dehydrogenase complex, component X
PHLDA3 pleckstrin homology-like domain, family A, member 3
PLCD1 phospholipase C, delta 1
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRR15L proline rich 15-like
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PTPN3 protein tyrosine phosphatase, non-receptor type 3
PYCARD PYD and CARD domain containing
RAI2 retinoic acid induced 2
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RUFY2 RUN and FYVE domain containing 2
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
SLC41A3 solute carrier family 41, member 3
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
TBK1 TANK-binding kinase 1
TEAD3 TEA domain family member 3
TKFC triokinase/FMN cyclase
TNK1 tyrosine kinase, non-receptor, 1
TOR3A torsin family 3, member A
TRIM9 tripartite motif containing 9
TSPYL2 TSPY-like 2
TTLL7 tubulin tyrosine ligase-like family member 7
USB1 U6 snRNA biogenesis 1
WDR76 WD repeat domain 76
ZDHHC18 zinc finger, DHHC-type containing 18
ZFP69B ZFP69 zinc finger protein B
ZNF197 zinc finger protein 197
ZNF611 zinc finger protein 611
ZNF804A zinc finger protein 804A
ZNF813 zinc finger protein 813
ZNF862 zinc finger protein 862
ZSCAN26 zinc finger and SCAN domain containing 26