native Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

402 genes co-occuring with the biological term native in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
A2M alpha-2-macroglobulin
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11
ABCC11 ATP-binding cassette, sub-family C (CFTR/MRP), member 11
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACE angiotensin I converting enzyme
ACTB actin, beta
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide
ADIPOQ adiponectin, C1Q and collagen domain containing
ADM adrenomedullin
ADORA2A adenosine A2a receptor
ADRA2B adrenoceptor alpha 2B
AGO2 argonaute RISC catalytic component 2
AGTR1 angiotensin II receptor, type 1
AGXT alanine-glyoxylate aminotransferase
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALB albumin
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALPL alkaline phosphatase, liver/bone/kidney
AMBP alpha-1-microglobulin/bikunin precursor
ANK1 ankyrin 1, erythrocytic
ANO1 anoctamin 1, calcium activated chloride channel
APOB apolipoprotein B
APP amyloid beta (A4) precursor protein
AQP4 aquaporin 4
AR androgen receptor
ARCN1 archain 1
ARRB1 arrestin, beta 1
ARRB2 arrestin, beta 2
ART4 ADP-ribosyltransferase 4 (Dombrock blood group)
ASIC1 acid sensing (proton gated) ion channel 1
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
ATP7A ATPase, Cu++ transporting, alpha polypeptide
ATXN1 ataxin 1
ATXN3 ataxin 3
B2M beta-2-microglobulin
BACE1 beta-site APP-cleaving enzyme 1
BAX BCL2-associated X protein
BCHE butyrylcholinesterase
BCR breakpoint cluster region
BMP1 bone morphogenetic protein 1
BMP4 bone morphogenetic protein 4
BMP8B bone morphogenetic protein 8b
BRCA1 breast cancer 1, early onset
BTK Bruton agammaglobulinemia tyrosine kinase
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
C1GALT1C1 C1GALT1-specific chaperone 1
C1QA complement component 1, q subcomponent, A chain
C3 complement component 3
C4B complement component 4B (Chido blood group)
C4BPA complement component 4 binding protein, alpha
CA7 carbonic anhydrase VII
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit
CALM3 calmodulin 3 (phosphorylase kinase, delta)
CASP10 caspase 10, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CBX1 chromobox homolog 1
CBX3 chromobox homolog 3
CBX5 chromobox homolog 5
CCAR2 cell cycle and apoptosis regulator 2
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CCM2 cerebral cavernous malformation 2
CCND1 cyclin D1
CD163 CD163 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD46 CD46 molecule, complement regulatory protein
CD69 CD69 molecule
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CES1 carboxylesterase 1
CES2 carboxylesterase 2
CFD complement factor D (adipsin)
CFH complement factor H
CFHR1 complement factor H-related 1
CFHR4 complement factor H-related 4
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CGB chorionic gonadotropin, beta polypeptide
CHMP4B charged multivesicular body protein 4B
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal)
CLCA2 chloride channel accessory 2
CLCN3 chloride channel, voltage-sensitive 3
CLDN16 claudin 16
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
CLPP caseinolytic mitochondrial matrix peptidase proteolytic subunit
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit
CNR2 cannabinoid receptor 2 (macrophage)
CPEB3 cytoplasmic polyadenylation element binding protein 3
CPT1A carnitine palmitoyltransferase 1A (liver)
CRP C-reactive protein, pentraxin-related
CRYAA crystallin, alpha A
CRYAB crystallin, alpha B
CRYGD crystallin, gamma D
CRYM crystallin, mu
CSF3 colony stimulating factor 3 (granulocyte)
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CUL4A cullin 4A
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR4 chemokine (C-X-C motif) receptor 4
CYBB cytochrome b-245, beta polypeptide
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DCLK1 doublecortin-like kinase 1
DCLRE1C DNA cross-link repair 1C
DDB1 damage-specific DNA binding protein 1, 127kDa
DDB2 damage-specific DNA binding protein 2, 48kDa
DDR1 discoidin domain receptor tyrosine kinase 1
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DEFB105A defensin, beta 105A
DIAPH1 diaphanous-related formin 1
DMTN dematin actin binding protein
DPP6 dipeptidyl-peptidase 6
DSG1 desmoglein 1
DUOXA2 dual oxidase maturation factor 2
ECE1 endothelin converting enzyme 1
EDN1 endothelin 1
EGFR epidermal growth factor receptor
EGLN1 egl-9 family hypoxia-inducible factor 1
ELN elastin
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EPAS1 endothelial PAS domain protein 1
EPS8 epidermal growth factor receptor pathway substrate 8
ERBB2 erb-b2 receptor tyrosine kinase 2
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ESR1 estrogen receptor 1
ETV6 ets variant 6
F10 coagulation factor X
F8 coagulation factor VIII, procoagulant component
FADD Fas (TNFRSF6)-associated via death domain
FAS Fas cell surface death receptor
FBN1 fibrillin 1
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23)
FEN1 flap structure-specific endonuclease 1
FGA fibrinogen alpha chain
FGF1 fibroblast growth factor 1 (acidic)
FGF14 fibroblast growth factor 14
FGG fibrinogen gamma chain
FLT3 fms-related tyrosine kinase 3
FMR1 fragile X mental retardation 1
FPGT fucose-1-phosphate guanylyltransferase
FST follistatin
FXN frataxin
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GCG glucagon
GCGR glucagon receptor
GEMIN7 gem (nuclear organelle) associated protein 7
GGCX gamma-glutamyl carboxylase
GJD2 gap junction protein, delta 2, 36kDa
GLO1 glyoxalase I
GLTP glycolipid transfer protein
GPR17 G protein-coupled receptor 17
GRIK2 glutamate receptor, ionotropic, kainate 2
GSTP1 glutathione S-transferase pi 1
GUCA2A guanylate cyclase activator 2A (guanylin)
GYPA glycophorin A (MNS blood group)
HBB hemoglobin, beta
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2
HCN3 hyperpolarization activated cyclic nucleotide gated potassium channel 3
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4
HCRTR1 hypocretin (orexin) receptor 1
HCRTR2 hypocretin (orexin) receptor 2
HDL3 Huntington-like neurodegenerative disorder 2
HHEX hematopoietically expressed homeobox
HIST1H2BA histone cluster 1, H2ba
HIST2H2AC histone cluster 2, H2ac
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HMCN1 hemicentin 1
HMOX2 heme oxygenase 2
HNF4A hepatocyte nuclear factor 4, alpha
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPG2 heparan sulfate proteoglycan 2
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
HTT huntingtin
ICAM1 intercellular adhesion molecule 1
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IGFBP3 insulin-like growth factor binding protein 3
IL10 interleukin 10
IL1B interleukin 1, beta
IL2 interleukin 2
IL3 interleukin 3
IL6 interleukin 6
IL7R interleukin 7 receptor
INS insulin
INSL3 insulin-like 3 (Leydig cell)
ISCU iron-sulfur cluster assembly enzyme
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITGB6 integrin, beta 6
JAK2 Janus kinase 2
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KCNQ2 potassium channel, voltage gated KQT-like subfamily Q, member 2
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3
KCTD21 potassium channel tetramerization domain containing 21
KCTD3 potassium channel tetramerization domain containing 3
KCTD6 potassium channel tetramerization domain containing 6
KIF5B kinesin family member 5B
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
KLF11 Kruppel-like factor 11
LAMP2 lysosomal-associated membrane protein 2
LDLR low density lipoprotein receptor
LEPR leptin receptor
LGALS1 lectin, galactoside-binding, soluble, 1
LIPG lipase, endothelial
LOXL1 lysyl oxidase-like 1
LPA lipoprotein, Lp(a)
LPGAT1 lysophosphatidylglycerol acyltransferase 1
MAPK7 mitogen-activated protein kinase 7
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
MAPT microtubule-associated protein tau
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
MBL2 mannose-binding lectin (protein C) 2, soluble
MGAM maltase-glucoamylase
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIR2909 microRNA 2909
MMP2 matrix metallopeptidase 2
MMP8 matrix metallopeptidase 8
MMP9 matrix metallopeptidase 9
MOG myelin oligodendrocyte glycoprotein
MSMB microseminoprotein, beta-
MT2A metallothionein 2A
MUC1 mucin 1, cell surface associated
MUC17 mucin 17, cell surface associated
N4BP2 NEDD4 binding protein 2
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit
NCOA1 nuclear receptor coactivator 1
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NEIL1 nei endonuclease VIII-like 1 (E. coli)
NELL1 NEL-like 1 (chicken)
NFAM1 NFAT activating protein with ITAM motif 1
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NGB neuroglobin
NGF nerve growth factor (beta polypeptide)
NISCH nischarin
NMNAT1 nicotinamide nucleotide adenylyltransferase 1
NPR1 natriuretic peptide receptor 1
NPR2 natriuretic peptide receptor 2
NR1I2 nuclear receptor subfamily 1, group I, member 2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NRD1 nardilysin (N-arginine dibasic convertase)
OGFR opioid growth factor receptor
OGG1 8-oxoguanine DNA glycosylase
OPN4 opsin 4
ORAI1 ORAI calcium release-activated calcium modulator 1
ORAI3 ORAI calcium release-activated calcium modulator 3
PABPN1 poly(A) binding protein, nuclear 1
PAEP progestagen-associated endometrial protein
PASD1 PAS domain containing 1
PAX6 paired box 6
PDCD6IP programmed cell death 6 interacting protein
PDIA3 protein disulfide isomerase family A, member 3
PEAR1 platelet endothelial aggregation receptor 1
PIGR polymeric immunoglobulin receptor
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIP prolactin-induced protein
PITX2 paired-like homeodomain 2
PKD1 polycystic kidney disease 1 (autosomal dominant)
PKD2 polycystic kidney disease 2 (autosomal dominant)
PLA2G16 phospholipase A2, group XVI
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLAU plasminogen activator, urokinase
PLG plasminogen
PPARA peroxisome proliferator-activated receptor alpha
PPARG peroxisome proliferator-activated receptor gamma
PPIA peptidylprolyl isomerase A (cyclophilin A)
PRDX4 peroxiredoxin 4
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRKCB protein kinase C, beta
PRKG1 protein kinase, cGMP-dependent, type I
PRNP prion protein
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PROS1 protein S (alpha)
PROZ protein Z, vitamin K-dependent plasma glycoprotein
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
PRTN3 proteinase 3
PSEN2 presenilin 2
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTH1R parathyroid hormone 1 receptor
PTH2R parathyroid hormone 2 receptor
PTPRC protein tyrosine phosphatase, receptor type, C
RAB11B RAB11B, member RAS oncogene family
RAB7A RAB7A, member RAS oncogene family
RANBP2 RAN binding protein 2
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RNASE3 ribonuclease, RNase A family, 3
RPA1 replication protein A1, 70kDa
RPLP0 ribosomal protein, large, P0
RPLP1 ribosomal protein, large, P1
RPLP2 ribosomal protein, large, P2
RXFP1 relaxin/insulin-like family peptide receptor 1
RXFP2 relaxin/insulin-like family peptide receptor 2
RYR2 ryanodine receptor 2 (cardiac)
S100A6 S100 calcium binding protein A6
SCN10A sodium channel, voltage gated, type X alpha subunit
SCN5A sodium channel, voltage gated, type V alpha subunit
SCN8A sodium channel, voltage gated, type VIII alpha subunit
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SCNN1B sodium channel, non voltage gated 1 beta subunit
SCNN1D sodium channel, non voltage gated 1 delta subunit
SCNN1G sodium channel, non voltage gated 1 gamma subunit
SELL selectin L
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA10 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1
SET SET nuclear proto-oncogene
SGOL1 shugoshin-like 1 (S. pombe)
SIRT1 sirtuin 1
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC26A5 solute carrier family 26 (anion exchanger), member 5
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SLC38A3 solute carrier family 38, member 3
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1
SLC44A2 solute carrier family 44 (choline transporter), member 2
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SMC2 structural maintenance of chromosomes 2
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
SOD1 superoxide dismutase 1, soluble
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
STAC3 SH3 and cysteine rich domain 3
STIM1 stromal interaction molecule 1
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
SULF2 sulfatase 2
SYK spleen tyrosine kinase
TACR1 tachykinin receptor 1
TACR2 tachykinin receptor 2
TACR3 tachykinin receptor 3
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TCP1 t-complex 1
TERT telomerase reverse transcriptase
TF transferrin
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TFPI2 tissue factor pathway inhibitor 2
TG thyroglobulin
TGM2 transglutaminase 2
TIGD3 tigger transposable element derived 3
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TIMP1 TIMP metallopeptidase inhibitor 1
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TMPRSS2 transmembrane protease, serine 2
TNF tumor necrosis factor
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TP53 tumor protein p53
TRAF3IP2 TRAF3 interacting protein 2
TRPA1 transient receptor potential cation channel, subfamily A, member 1
TRPC1 transient receptor potential cation channel, subfamily C, member 1
TRPC3 transient receptor potential cation channel, subfamily C, member 3
TRPC7 transient receptor potential cation channel, subfamily C, member 7
TRPV3 transient receptor potential cation channel, subfamily V, member 3
TRPV4 transient receptor potential cation channel, subfamily V, member 4
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TSHB thyroid stimulating hormone, beta
TTR transthyretin
TXNDC12 thioredoxin domain containing 12 (endoplasmic reticulum)
TXNL4B thioredoxin-like 4B
UTS2R urotensin 2 receptor
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C
VCAM1 vascular cell adhesion molecule 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VKORC1 vitamin K epoxide reductase complex, subunit 1
WT1 Wilms tumor 1
XCL1 chemokine (C motif) ligand 1
ZP3 zona pellucida glycoprotein 3 (sperm receptor)