natural killer cell activation Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description The change in morphology and behavior of a natural killer cell in response to a cytokine, chemokine, cellular ligand, or soluble factor. (Gene Ontology, GO_0030101)
External Link http://amigo.geneontology.org/amigo/term/GO:0030101
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Genes

49 genes participating in the natural killer cell activation biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
AXL AXL receptor tyrosine kinase
BAG6 BCL2-associated athanogene 6
CASP8 caspase 8, apoptosis-related cysteine peptidase
CD2 CD2 molecule
CD244 CD244 molecule, natural killer cell receptor 2B4
CD48 CD48 molecule
CLSTN1 calsyntenin 1
ELF4 E74-like factor 4 (ets domain transcription factor)
EMP2 epithelial membrane protein 2
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FYN FYN proto-oncogene, Src family tyrosine kinase
IFNA1 interferon, alpha 1
IFNA10 interferon, alpha 10
IFNA14 interferon, alpha 14
IFNA16 interferon, alpha 16
IFNA17 interferon, alpha 17
IFNA2 interferon, alpha 2
IFNA21 interferon, alpha 21
IFNA4 interferon, alpha 4
IFNA5 interferon, alpha 5
IFNA6 interferon, alpha 6
IFNA7 interferon, alpha 7
IFNA8 interferon, alpha 8
IFNB1 interferon, beta 1, fibroblast
IFNE interferon, epsilon
IFNK interferon, kappa
IFNW1 interferon, omega 1
IL12B interleukin 12B
IL2 interleukin 2
IL21R interleukin 21 receptor
KAT7 K(lysine) acetyltransferase 7
KIR3DS1 killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1
KLRK1 killer cell lectin-like receptor subfamily K, member 1
NCR1 natural cytotoxicity triggering receptor 1
NCR3 natural cytotoxicity triggering receptor 3
NFIL3 nuclear factor, interleukin 3 regulated
PBX1 pre-B-cell leukemia homeobox 1
PRDX1 peroxiredoxin 1
PTPRC protein tyrosine phosphatase, receptor type, C
RABL3 RAB, member of RAS oncogene family-like 3
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
SH2D1A SH2 domain containing 1A
SLAMF7 SLAM family member 7
SNX27 sorting nexin family member 27
TOX thymocyte selection-associated high mobility group box
ULBP1 UL16 binding protein 1
ULBP2 UL16 binding protein 2
ULBP3 UL16 binding protein 3
VAV1 vav 1 guanine nucleotide exchange factor