natural killer cell mediated cytotoxicity Gene Set

Dataset GO Biological Process Annotations 2023
Category structural or functional annotations
Type biological process
Description The directed killing of a target cell by a natural killer cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors. (Gene Ontology, GO_0042267)
External Link http://amigo.geneontology.org/amigo/term/GO_0042267
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Genes

25 genes participating in the natural killer cell mediated cytotoxicity biological process from the curated GO Biological Process Annotations 2023 dataset.

Symbol Name
ARL8B ADP-ribosylation factor-like 8B
CD2 CD2 molecule
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma
CLEC2A C-type lectin domain family 2, member A
CORO1A coronin, actin binding protein, 1A
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
KIF5B kinesin family member 5B
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
KLRF2 killer cell lectin-like receptor subfamily F, member 2
KLRK1 killer cell lectin-like receptor subfamily K, member 1
LYST lysosomal trafficking regulator
MICA MHC class I polypeptide-related sequence A
NKG7 natural killer cell granule protein 7
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
RAET1E retinoic acid early transcript 1E
RAET1G retinoic acid early transcript 1G
SLAMF7 SLAM family member 7
TUBB2A tubulin, beta 2A class IIa
TUBB4B tubulin, beta 4B class IVb
ULBP1 UL16 binding protein 1
ULBP2 UL16 binding protein 2
ULBP3 UL16 binding protein 3
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VAMP7 vesicle-associated membrane protein 7