| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the nefopam-2317 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ADAM22 | ADAM metallopeptidase domain 22 |
| AKR1D1 | aldo-keto reductase family 1, member D1 |
| ALDOB | aldolase B, fructose-bisphosphate |
| APOC4 | apolipoprotein C-IV |
| APOLD1 | apolipoprotein L domain containing 1 |
| ARHGEF26 | Rho guanine nucleotide exchange factor (GEF) 26 |
| ASB1 | ankyrin repeat and SOCS box containing 1 |
| AVIL | advillin |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| C6 | complement component 6 |
| CAMKK2 | calcium/calmodulin-dependent protein kinase kinase 2, beta |
| CD200 | CD200 molecule |
| CD8A | CD8a molecule |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CPEB1 | cytoplasmic polyadenylation element binding protein 1 |
| CPQ | carboxypeptidase Q |
| CRHR2 | corticotropin releasing hormone receptor 2 |
| CXXC4 | CXXC finger protein 4 |
| CYP4A11 | cytochrome P450, family 4, subfamily A, polypeptide 11 |
| DGCR2 | DiGeorge syndrome critical region gene 2 |
| DICER1 | dicer 1, ribonuclease type III |
| DUSP9 | dual specificity phosphatase 9 |
| ECE1 | endothelin converting enzyme 1 |
| EGFR | epidermal growth factor receptor |
| EGR3 | early growth response 3 |
| EPHB2 | EPH receptor B2 |
| ERCC2 | excision repair cross-complementation group 2 |
| ESR1 | estrogen receptor 1 |
| FCAR | Fc fragment of IgA receptor |
| FCMR | Fc fragment of IgM receptor |
| FGFR1 | fibroblast growth factor receptor 1 |
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 |
| GATA2 | GATA binding protein 2 |
| GMPR | guanosine monophosphate reductase |
| GRIP2 | glutamate receptor interacting protein 2 |
| GSTTP1 | glutathione S-transferase theta pseudogene 1 |
| GUCY2D | guanylate cyclase 2D, membrane (retina-specific) |
| GYG2 | glycogenin 2 |
| HAAO | 3-hydroxyanthranilate 3,4-dioxygenase |
| HEY2 | hes-related family bHLH transcription factor with YRPW motif 2 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| HPSE2 | heparanase 2 (inactive) |
| HYMAI | hydatidiform mole associated and imprinted (non-protein coding) |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| IRF4 | interferon regulatory factor 4 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
| ITPKA | inositol-trisphosphate 3-kinase A |
| KLK13 | kallikrein-related peptidase 13 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LILRB2 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 |
| LIN28A | lin-28 homolog A (C. elegans) |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAN1C1 | mannosidase, alpha, class 1C, member 1 |
| MGAT3 | mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase |
| MST1L | macrophage stimulating 1-like |
| MTOR | mechanistic target of rapamycin (serine/threonine kinase) |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NF1 | neurofibromin 1 |
| NME5 | NME/NM23 family member 5 |
| NTF3 | neurotrophin 3 |
| OSGIN2 | oxidative stress induced growth inhibitor family member 2 |
| PCNX | pecanex homolog (Drosophila) |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PDGFB | platelet-derived growth factor beta polypeptide |
| PIGN | phosphatidylinositol glycan anchor biosynthesis, class N |
| POU4F1 | POU class 4 homeobox 1 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PRKCI | protein kinase C, iota |
| PSAT1 | phosphoserine aminotransferase 1 |
| PTCRA | pre T-cell antigen receptor alpha |
| RAD52 | RAD52 homolog (S. cerevisiae) |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
| RIMS2 | regulating synaptic membrane exocytosis 2 |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RPGRIP1L | RPGRIP1-like |
| RPS3A | ribosomal protein S3A |
| S100A1 | S100 calcium binding protein A1 |
| S100A13 | S100 calcium binding protein A13 |
| SBNO2 | strawberry notch homolog 2 (Drosophila) |
| SIGLEC7 | sialic acid binding Ig-like lectin 7 |
| SIRT5 | sirtuin 5 |
| SMAD1 | SMAD family member 1 |
| SNX1 | sorting nexin 1 |
| SOAT2 | sterol O-acyltransferase 2 |
| SPAM1 | sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) |
| SPEG | SPEG complex locus |
| SYK | spleen tyrosine kinase |
| TBL1Y | transducin (beta)-like 1, Y-linked |
| TCHH | trichohyalin |
| TECPR2 | tectonin beta-propeller repeat containing 2 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TREM1 | triggering receptor expressed on myeloid cells 1 |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| WIPI2 | WD repeat domain, phosphoinositide interacting 2 |
| WSCD1 | WSC domain containing 1 |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZNF589 | zinc finger protein 589 |
| Symbol | Name |
|---|---|
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| ATP6V0A4 | ATPase, H+ transporting, lysosomal V0 subunit a4 |
| B3GNT4 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 |
| BHLHB9 | basic helix-loop-helix domain containing, class B, 9 |
| BMP10 | bone morphogenetic protein 10 |
| BTBD7 | BTB (POZ) domain containing 7 |
| C11ORF80 | chromosome 11 open reading frame 80 |
| C2ORF68 | chromosome 2 open reading frame 68 |
| C3 | complement component 3 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CA11 | carbonic anhydrase XI |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CAMTA2 | calmodulin binding transcription activator 2 |
| CCDC132 | coiled-coil domain containing 132 |
| CCDC186 | coiled-coil domain containing 186 |
| CENPC | centromere protein C |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| CRABP1 | cellular retinoic acid binding protein 1 |
| CRELD1 | cysteine-rich with EGF-like domains 1 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DNAL4 | dynein, axonemal, light chain 4 |
| DNM1 | dynamin 1 |
| DOK2 | docking protein 2, 56kDa |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FAM169A | family with sequence similarity 169, member A |
| FILIP1L | filamin A interacting protein 1-like |
| FKBP5 | FK506 binding protein 5 |
| FRK | fyn-related Src family tyrosine kinase |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HIST1H2BJ | histone cluster 1, H2bj |
| HYI | hydroxypyruvate isomerase (putative) |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KCNN2 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 |
| KEL | Kell blood group, metallo-endopeptidase |
| KIAA0125 | KIAA0125 |
| KIAA1107 | KIAA1107 |
| KIF13A | kinesin family member 13A |
| LHX1 | LIM homeobox 1 |
| MAGEB2 | melanoma antigen family B2 |
| MAGEF1 | melanoma antigen family F1 |
| MAL | mal, T-cell differentiation protein |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MEFV | Mediterranean fever |
| MMP2 | matrix metallopeptidase 2 |
| MOCS1 | molybdenum cofactor synthesis 1 |
| MON1B | MON1 secretory trafficking family member B |
| MYO1F | myosin IF |
| NCALD | neurocalcin delta |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NIPAL2 | NIPA-like domain containing 2 |
| NLRX1 | NLR family member X1 |
| NXPH4 | neurexophilin 4 |
| NYNRIN | NYN domain and retroviral integrase containing |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PDZD8 | PDZ domain containing 8 |
| POLL | polymerase (DNA directed), lambda |
| PRKACG | protein kinase, cAMP-dependent, catalytic, gamma |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| RAB3D | RAB3D, member RAS oncogene family |
| RNF39 | ring finger protein 39 |
| RP2 | retinitis pigmentosa 2 (X-linked recessive) |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| STX1A | syntaxin 1A (brain) |
| SYNC | syncoilin, intermediate filament protein |
| TBKBP1 | TBK1 binding protein 1 |
| TLR2 | toll-like receptor 2 |
| TMUB2 | transmembrane and ubiquitin-like domain containing 2 |
| TOM1 | target of myb1 (chicken) |
| TRIM21 | tripartite motif containing 21 |
| TRIM5 | tripartite motif containing 5 |
| TTBK2 | tau tubulin kinase 2 |
| TTC30A | tetratricopeptide repeat domain 30A |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| USP20 | ubiquitin specific peptidase 20 |
| USP36 | ubiquitin specific peptidase 36 |
| VPS9D1 | VPS9 domain containing 1 |
| WDR91 | WD repeat domain 91 |
| XK | X-linked Kx blood group |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZDHHC24 | zinc finger, DHHC-type containing 24 |
| ZFHX2 | zinc finger homeobox 2 |
| ZNF324 | zinc finger protein 324 |
| ZNF350 | zinc finger protein 350 |
| ZNF446 | zinc finger protein 446 |
| ZNF665 | zinc finger protein 665 |
