| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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194 genes differentially expressed following the nefopam-2355 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
| ADCY9 | adenylate cyclase 9 |
| AMDHD2 | amidohydrolase domain containing 2 |
| APBB1IP | amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 |
| ARL15 | ADP-ribosylation factor-like 15 |
| ARL2BP | ADP-ribosylation factor-like 2 binding protein |
| ATF6B | activating transcription factor 6 beta |
| AURKA | aurora kinase A |
| C19ORF66 | chromosome 19 open reading frame 66 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) |
| CNNM1 | cyclin and CBS domain divalent metal cation transport mediator 1 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| DOCK5 | dedicator of cytokinesis 5 |
| DOHH | deoxyhypusine hydroxylase/monooxygenase |
| DPY19L1 | dpy-19-like 1 (C. elegans) |
| DST | dystonin |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
| ECM1 | extracellular matrix protein 1 |
| EHBP1L1 | EH domain binding protein 1-like 1 |
| ELK1 | ELK1, member of ETS oncogene family |
| ENTPD4 | ectonucleoside triphosphate diphosphohydrolase 4 |
| F12 | coagulation factor XII (Hageman factor) |
| FBXO46 | F-box protein 46 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FGF6 | fibroblast growth factor 6 |
| FOXN2 | forkhead box N2 |
| FRMPD1 | FERM and PDZ domain containing 1 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GABRA4 | gamma-aminobutyric acid (GABA) A receptor, alpha 4 |
| GEMIN4 | gem (nuclear organelle) associated protein 4 |
| GIF | gastric intrinsic factor (vitamin B synthesis) |
| GK | glycerol kinase |
| GPRC5D | G protein-coupled receptor, class C, group 5, member D |
| HIPK3 | homeodomain interacting protein kinase 3 |
| HLA-DQB2 | major histocompatibility complex, class II, DQ beta 2 |
| IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) |
| IL22 | interleukin 22 |
| IL5RA | interleukin 5 receptor, alpha |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KIAA0753 | KIAA0753 |
| KLHL25 | kelch-like family member 25 |
| LOC157562 | uncharacterized LOC157562 |
| MAPK8 | mitogen-activated protein kinase 8 |
| MAPK8IP2 | mitogen-activated protein kinase 8 interacting protein 2 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MKL1 | megakaryoblastic leukemia (translocation) 1 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MORC1 | MORC family CW-type zinc finger 1 |
| MRAS | muscle RAS oncogene homolog |
| MREG | melanoregulin |
| MYOF | myoferlin |
| N4BP2L2-IT2 | N4BPL2 intronic transcript 2 |
| NCR2 | natural cytotoxicity triggering receptor 2 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NOTCH3 | notch 3 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 |
| PATZ1 | POZ (BTB) and AT hook containing zinc finger 1 |
| PDE12 | phosphodiesterase 12 |
| PGAP3 | post-GPI attachment to proteins 3 |
| PGLYRP4 | peptidoglycan recognition protein 4 |
| PIP | prolactin-induced protein |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma |
| PPP5C | protein phosphatase 5, catalytic subunit |
| PQBP1 | polyglutamine binding protein 1 |
| PTH2R | parathyroid hormone 2 receptor |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
| RNF122 | ring finger protein 122 |
| RNF39 | ring finger protein 39 |
| RUNX1 | runt-related transcription factor 1 |
| SELPLG | selectin P ligand |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 |
| SMAD3 | SMAD family member 3 |
| SOS1 | son of sevenless homolog 1 (Drosophila) |
| SRR | serine racemase |
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced |
| SYNGR1 | synaptogyrin 1 |
| SYNJ2 | synaptojanin 2 |
| TADA2A | transcriptional adaptor 2A |
| TECPR2 | tectonin beta-propeller repeat containing 2 |
| TEX261 | testis expressed 261 |
| TMEM51 | transmembrane protein 51 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 |
| TPM2 | tropomyosin 2 (beta) |
| TRIM25 | tripartite motif containing 25 |
| UHRF1BP1L | UHRF1 binding protein 1-like |
| VPS13D | vacuolar protein sorting 13 homolog D (S. cerevisiae) |
| VPS53 | vacuolar protein sorting 53 homolog (S. cerevisiae) |
| WNT16 | wingless-type MMTV integration site family, member 16 |
| ZFYVE9 | zinc finger, FYVE domain containing 9 |
| ZNF235 | zinc finger protein 235 |
| ZNF589 | zinc finger protein 589 |
| Symbol | Name |
|---|---|
| ACTR3B | ARP3 actin-related protein 3 homolog B (yeast) |
| ACYP1 | acylphosphatase 1, erythrocyte (common) type |
| ADGRE2 | adhesion G protein-coupled receptor E2 |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 |
| ALAD | aminolevulinate dehydratase |
| ALDOC | aldolase C, fructose-bisphosphate |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| BMP15 | bone morphogenetic protein 15 |
| C3 | complement component 3 |
| C9ORF91 | chromosome 9 open reading frame 91 |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CAPN1 | calpain 1, (mu/I) large subunit |
| CCDC85C | coiled-coil domain containing 85C |
| CCNT1 | cyclin T1 |
| CDK3 | cyclin-dependent kinase 3 |
| CHMP1A | charged multivesicular body protein 1A |
| CINP | cyclin-dependent kinase 2 interacting protein |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLEC7A | C-type lectin domain family 7, member A |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| CXCR2 | chemokine (C-X-C motif) receptor 2 |
| DDN | dendrin |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) |
| DTX4 | deltex 4, E3 ubiquitin ligase |
| EFCAB2 | EF-hand calcium binding domain 2 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FBXL15 | F-box and leucine-rich repeat protein 15 |
| FILIP1L | filamin A interacting protein 1-like |
| FPGS | folylpolyglutamate synthase |
| GNL1 | guanine nucleotide binding protein-like 1 |
| GPATCH2 | G patch domain containing 2 |
| GPR137B | G protein-coupled receptor 137B |
| GPR22 | G protein-coupled receptor 22 |
| GPR27 | G protein-coupled receptor 27 |
| HDAC5 | histone deacetylase 5 |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H4J | histone cluster 1, H4j |
| ICK | intestinal cell (MAK-like) kinase |
| IL2RG | interleukin 2 receptor, gamma |
| ITGB7 | integrin, beta 7 |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 |
| LAX1 | lymphocyte transmembrane adaptor 1 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| MBIP | MAP3K12 binding inhibitory protein 1 |
| MBNL3 | muscleblind-like splicing regulator 3 |
| MECR | mitochondrial trans-2-enoyl-CoA reductase |
| MGC12488 | |
| MILR1 | mast cell immunoglobulin-like receptor 1 |
| MUM1 | melanoma associated antigen (mutated) 1 |
| NSUN3 | NOP2/Sun domain family, member 3 |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| NUBPL | nucleotide binding protein-like |
| OSBPL2 | oxysterol binding protein-like 2 |
| PDE6C | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
| PIGK | phosphatidylinositol glycan anchor biosynthesis, class K |
| PKN1 | protein kinase N1 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor |
| PRAF2 | PRA1 domain family, member 2 |
| PTX3 | pentraxin 3, long |
| RAB33B | RAB33B, member RAS oncogene family |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RCAN3 | RCAN family member 3 |
| RNF121 | ring finger protein 121 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| RWDD3 | RWD domain containing 3 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SIRT6 | sirtuin 6 |
| SLC10A3 | solute carrier family 10, member 3 |
| SLC4A2 | solute carrier family 4 (anion exchanger), member 2 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SMR3A | submaxillary gland androgen regulated protein 3A |
| SREK1IP1 | SREK1-interacting protein 1 |
| SRGAP2 | SLIT-ROBO Rho GTPase activating protein 2 |
| STAG3L1 | stromal antigen 3-like 1 (pseudogene) |
| TBX19 | T-box 19 |
| TCEA2 | transcription elongation factor A (SII), 2 |
| TIGD6 | tigger transposable element derived 6 |
| TLN1 | talin 1 |
| TMEM127 | transmembrane protein 127 |
| TMEM212 | transmembrane protein 212 |
| TPCN1 | two pore segment channel 1 |
| TRABD | TraB domain containing |
| TRIM68 | tripartite motif containing 68 |
| TSPAN13 | tetraspanin 13 |
| VNN2 | vanin 2 |
| XYLT2 | xylosyltransferase II |
| ZBED8 | zinc finger, BED-type containing 8 |
| ZDHHC24 | zinc finger, DHHC-type containing 24 |
| ZNF280D | zinc finger protein 280D |
| ZNF324 | zinc finger protein 324 |
| ZNF506 | zinc finger protein 506 |
| ZNF571 | zinc finger protein 571 |
| ZSCAN31 | zinc finger and SCAN domain containing 31 |
