| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the nefopam-3627 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACSBG2 | acyl-CoA synthetase bubblegum family member 2 |
| ARHGAP1 | Rho GTPase activating protein 1 |
| ATXN7L1 | ataxin 7-like 1 |
| BEST1 | bestrophin 1 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| BRF1 | BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit |
| C7 | complement component 7 |
| CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit |
| CCL13 | chemokine (C-C motif) ligand 13 |
| CCL5 | chemokine (C-C motif) ligand 5 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) |
| CHRM4 | cholinergic receptor, muscarinic 4 |
| CHST3 | carbohydrate (chondroitin 6) sulfotransferase 3 |
| CLDN18 | claudin 18 |
| CMAHP | cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene |
| COL3A1 | collagen, type III, alpha 1 |
| CTIF | CBP80/20-dependent translation initiation factor |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) |
| DCT | dopachrome tautomerase |
| DDX28 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| DNAJC16 | DnaJ (Hsp40) homolog, subfamily C, member 16 |
| DNASE2B | deoxyribonuclease II beta |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A |
| EGFR | epidermal growth factor receptor |
| ELOVL2 | ELOVL fatty acid elongase 2 |
| EPB41L4B | erythrocyte membrane protein band 4.1 like 4B |
| EPM2A | epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) |
| FHL1 | four and a half LIM domains 1 |
| FLOT1 | flotillin 1 |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 |
| FOXE1 | forkhead box E1 |
| FRS3 | fibroblast growth factor receptor substrate 3 |
| GALR3 | galanin receptor 3 |
| GJA4 | gap junction protein, alpha 4, 37kDa |
| GJA8 | gap junction protein, alpha 8, 50kDa |
| GLRA3 | glycine receptor, alpha 3 |
| GVINP1 | GTPase, very large interferon inducible pseudogene 1 |
| GYG2 | glycogenin 2 |
| HAB1 | B1 for mucin |
| HECW1 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 |
| HOXB3 | homeobox B3 |
| ICA1 | islet cell autoantigen 1, 69kDa |
| IFNA16 | interferon, alpha 16 |
| INA | internexin neuronal intermediate filament protein, alpha |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 |
| KIR3DX1 | killer cell immunoglobulin-like receptor, three domains, X1 |
| KRIT1 | KRIT1, ankyrin repeat containing |
| LTC4S | leukotriene C4 synthase |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAS1 | MAS1 proto-oncogene, G protein-coupled receptor |
| MAU2 | MAU2 sister chromatid cohesion factor |
| MGAT3 | mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MPPE1 | metallophosphoesterase 1 |
| MYBPC3 | myosin binding protein C, cardiac |
| MYH2 | myosin, heavy chain 2, skeletal muscle, adult |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NOX5 | NADPH oxidase, EF-hand calcium binding domain 5 |
| NRF1 | nuclear respiratory factor 1 |
| OR1G1 | olfactory receptor, family 1, subfamily G, member 1 |
| OTOR | otoraplin |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 |
| PAPPA2 | pappalysin 2 |
| PMS2P3 | postmeiotic segregation increased 2 pseudogene 3 |
| PRG4 | proteoglycan 4 |
| PRKACA | protein kinase, cAMP-dependent, catalytic, alpha |
| PRL | prolactin |
| PSG3 | pregnancy specific beta-1-glycoprotein 3 |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| PVR | poliovirus receptor |
| RAB40C | RAB40C, member RAS oncogene family |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 |
| RND1 | Rho family GTPase 1 |
| RRBP1 | ribosome binding protein 1 |
| RRH | retinal pigment epithelium-derived rhodopsin homolog |
| SH3GL3 | SH3-domain GRB2-like 3 |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SLC13A2 | solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2 |
| SLC14A2 | solute carrier family 14 (urea transporter), member 2 |
| SLC16A5 | solute carrier family 16 (monocarboxylate transporter), member 5 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 |
| SRPK2 | SRSF protein kinase 2 |
| STAT2 | signal transducer and activator of transcription 2, 113kDa |
| SULT4A1 | sulfotransferase family 4A, member 1 |
| SYN2 | synapsin II |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TEX14 | testis expressed 14 |
| TMC6 | transmembrane channel-like 6 |
| TP63 | tumor protein p63 |
| TULP1 | tubby like protein 1 |
| URB1 | URB1 ribosome biogenesis 1 homolog (S. cerevisiae) |
| VCAN | versican |
| WDR62 | WD repeat domain 62 |
| XYLB | xylulokinase homolog (H. influenzae) |
| ZFP64 | ZFP64 zinc finger protein |
| Symbol | Name |
|---|---|
| ABCB8 | ATP-binding cassette, sub-family B (MDR/TAP), member 8 |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| ARHGAP4 | Rho GTPase activating protein 4 |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CBX7 | chromobox homolog 7 |
| CD53 | CD53 molecule |
| CGA | glycoprotein hormones, alpha polypeptide |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CLSTN2 | calsyntenin 2 |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| CPNE7 | copine VII |
| CRY2 | cryptochrome circadian clock 2 |
| CSTA | cystatin A (stefin A) |
| CYP2R1 | cytochrome P450, family 2, subfamily R, polypeptide 1 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DOK5 | docking protein 5 |
| EPPK1 | epiplakin 1 |
| ERCC4 | excision repair cross-complementation group 4 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FBXO2 | F-box protein 2 |
| FBXW12 | F-box and WD repeat domain containing 12 |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GFI1 | growth factor independent 1 transcription repressor |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GNG13 | guanine nucleotide binding protein (G protein), gamma 13 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GPR143 | G protein-coupled receptor 143 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HCAR3 | hydroxycarboxylic acid receptor 3 |
| HDAC7 | histone deacetylase 7 |
| HIST1H1D | histone cluster 1, H1d |
| HMHA1 | histocompatibility (minor) HA-1 |
| HOXA4 | homeobox A4 |
| HOXC10 | homeobox C10 |
| IFNA17 | interferon, alpha 17 |
| IL18 | interleukin 18 |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| KCNIP1 | Kv channel interacting protein 1 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KIAA1107 | KIAA1107 |
| KLHL25 | kelch-like family member 25 |
| LHX6 | LIM homeobox 6 |
| LIF | leukemia inhibitory factor |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| MAPK10 | mitogen-activated protein kinase 10 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) |
| MMP17 | matrix metallopeptidase 17 (membrane-inserted) |
| MTA2 | metastasis associated 1 family, member 2 |
| MYOZ3 | myozenin 3 |
| NME5 | NME/NM23 family member 5 |
| NPTX2 | neuronal pentraxin II |
| NPY4R | neuropeptide Y receptor Y4 |
| NYNRIN | NYN domain and retroviral integrase containing |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) |
| PLCD1 | phospholipase C, delta 1 |
| PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa |
| RAB3D | RAB3D, member RAS oncogene family |
| RCAN3 | RCAN family member 3 |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RPAP2 | RNA polymerase II associated protein 2 |
| RPH3A | rabphilin 3A |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| SLC12A6 | solute carrier family 12 (potassium/chloride transporter), member 6 |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
| SLC43A1 | solute carrier family 43 (amino acid system L transporter), member 1 |
| SLC52A1 | solute carrier family 52 (riboflavin transporter), member 1 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SLIT2 | slit homolog 2 (Drosophila) |
| SND1-IT1 | SND1 intronic transcript 1 |
| SSTR4 | somatostatin receptor 4 |
| STAG3L1 | stromal antigen 3-like 1 (pseudogene) |
| STEAP4 | STEAP family member 4 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) |
| TARP | TCR gamma alternate reading frame protein |
| TBKBP1 | TBK1 binding protein 1 |
| TEP1 | telomerase-associated protein 1 |
| TLR2 | toll-like receptor 2 |
| TRAIP | TRAF interacting protein |
| TUBA4B | tubulin, alpha 4b |
| UBQLN4 | ubiquilin 4 |
| UNC119 | unc-119 homolog (C. elegans) |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| WDR76 | WD repeat domain 76 |
| ZNF428 | zinc finger protein 428 |
| ZNF652 | zinc finger protein 652 |
| ZNF721 | zinc finger protein 721 |
| ZSCAN2 | zinc finger and SCAN domain containing 2 |
