| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the nefopam-3730 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACE | angiotensin I converting enzyme |
| ACTA1 | actin, alpha 1, skeletal muscle |
| AKAP13 | A kinase (PRKA) anchor protein 13 |
| AMPD3 | adenosine monophosphate deaminase 3 |
| ANGPTL2 | angiopoietin-like 2 |
| ANKRD26 | ankyrin repeat domain 26 |
| ARTN | artemin |
| ATF7 | activating transcription factor 7 |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous |
| BAIAP2 | BAI1-associated protein 2 |
| BBC3 | BCL2 binding component 3 |
| BCAT2 | branched chain amino-acid transaminase 2, mitochondrial |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| CCDC57 | coiled-coil domain containing 57 |
| CD33 | CD33 molecule |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CHRNG | cholinergic receptor, nicotinic, gamma (muscle) |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 |
| CPZ | carboxypeptidase Z |
| CRAT | carnitine O-acetyltransferase |
| CREB3L1 | cAMP responsive element binding protein 3-like 1 |
| CRHR2 | corticotropin releasing hormone receptor 2 |
| CRTC1 | CREB regulated transcription coactivator 1 |
| DKFZP434C153 | DKFZP434C153 protein |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| DOCK6 | dedicator of cytokinesis 6 |
| DSCC1 | DNA replication and sister chromatid cohesion 1 |
| DTNA | dystrobrevin, alpha |
| EBF2 | early B-cell factor 2 |
| EGR1 | early growth response 1 |
| ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| ESR1 | estrogen receptor 1 |
| FAM212B | family with sequence similarity 212, member B |
| FANCA | Fanconi anemia, complementation group A |
| FBXO22 | F-box protein 22 |
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 |
| GJA4 | gap junction protein, alpha 4, 37kDa |
| GPD2 | glycerol-3-phosphate dehydrogenase 2 (mitochondrial) |
| GPER1 | G protein-coupled estrogen receptor 1 |
| GPR19 | G protein-coupled receptor 19 |
| GRM1 | glutamate receptor, metabotropic 1 |
| GSTM5 | glutathione S-transferase mu 5 |
| HAAO | 3-hydroxyanthranilate 3,4-dioxygenase |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 |
| IL10RA | interleukin 10 receptor, alpha |
| IL1RN | interleukin 1 receptor antagonist |
| INO80D | INO80 complex subunit D |
| ITIH3 | inter-alpha-trypsin inhibitor heavy chain 3 |
| JAK3 | Janus kinase 3 |
| KAT8 | K(lysine) acetyltransferase 8 |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 |
| KIAA1109 | KIAA1109 |
| KLF13 | Kruppel-like factor 13 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LIMD1 | LIM domains containing 1 |
| LIMK2 | LIM domain kinase 2 |
| LIPG | lipase, endothelial |
| LOC100294391 | uncharacterized LOC100294391 |
| LTB4R | leukotriene B4 receptor |
| MAP4K1 | mitogen-activated protein kinase kinase kinase kinase 1 |
| MC5R | melanocortin 5 receptor |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MMP10 | matrix metallopeptidase 10 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) |
| MST1L | macrophage stimulating 1-like |
| MTOR | mechanistic target of rapamycin (serine/threonine kinase) |
| MUC13 | mucin 13, cell surface associated |
| MYEF2 | myelin expression factor 2 |
| NRP1 | neuropilin 1 |
| ONECUT2 | one cut homeobox 2 |
| OR3A3 | olfactory receptor, family 3, subfamily A, member 3 |
| PALM | paralemmin |
| PCDHB3 | protocadherin beta 3 |
| PIK3R5 | phosphoinositide-3-kinase, regulatory subunit 5 |
| PLEKHS1 | pleckstrin homology domain containing, family S member 1 |
| PLK4 | polo-like kinase 4 |
| POU2F3 | POU class 2 homeobox 3 |
| PRKCE | protein kinase C, epsilon |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 |
| RAB6B | RAB6B, member RAS oncogene family |
| RASA3 | RAS p21 protein activator 3 |
| RASL11B | RAS-like, family 11, member B |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RPH3A | rabphilin 3A |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SEMA4F | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F |
| SGCD | sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) |
| SLC30A4 | solute carrier family 30 (zinc transporter), member 4 |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| SYNGR4 | synaptogyrin 4 |
| TAOK2 | TAO kinase 2 |
| TET3 | tet methylcytosine dioxygenase 3 |
| TLDC1 | TBC/LysM-associated domain containing 1 |
| TLK1 | tousled-like kinase 1 |
| VPS9D1 | VPS9 domain containing 1 |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZNF287 | zinc finger protein 287 |
| Symbol | Name |
|---|---|
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
| AHSG | alpha-2-HS-glycoprotein |
| AK5 | adenylate kinase 5 |
| ALPK3 | alpha-kinase 3 |
| APOBEC2 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 |
| ARHGAP24 | Rho GTPase activating protein 24 |
| ASB13 | ankyrin repeat and SOCS box containing 13 |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| AURKC | aurora kinase C |
| C17ORF70 | chromosome 17 open reading frame 70 |
| C3 | complement component 3 |
| C9ORF40 | chromosome 9 open reading frame 40 |
| CARD8 | caspase recruitment domain family, member 8 |
| CCDC7 | coiled-coil domain containing 7 |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CDH19 | cadherin 19, type 2 |
| CES3 | carboxylesterase 3 |
| CFAP69 | cilia and flagella associated protein 69 |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CLCA1 | chloride channel accessory 1 |
| CNPY4 | canopy FGF signaling regulator 4 |
| CNTN1 | contactin 1 |
| COLGALT2 | collagen beta(1-O)galactosyltransferase 2 |
| CYB5R2 | cytochrome b5 reductase 2 |
| CYP2W1 | cytochrome P450, family 2, subfamily W, polypeptide 1 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DNM3 | dynamin 3 |
| EGFL7 | EGF-like-domain, multiple 7 |
| EPN1 | epsin 1 |
| ERCC4 | excision repair cross-complementation group 4 |
| FAM120C | family with sequence similarity 120C |
| FAM189A2 | family with sequence similarity 189, member A2 |
| FBXO46 | F-box protein 46 |
| FKRP | fukutin related protein |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| HAO2 | hydroxyacid oxidase 2 (long chain) |
| HIST1H1D | histone cluster 1, H1d |
| HPN | hepsin |
| HYI | hydroxypyruvate isomerase (putative) |
| IL2 | interleukin 2 |
| IL22 | interleukin 22 |
| INE1 | inactivation escape 1 (non-protein coding) |
| KLF3 | Kruppel-like factor 3 (basic) |
| KRT9 | keratin 9, type I |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LMO7 | LIM domain 7 |
| LMTK1 | lemur tail kinase 1 |
| LMTK2 | lemur tyrosine kinase 2 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| LY86 | lymphocyte antigen 86 |
| LYPD3 | LY6/PLAUR domain containing 3 |
| MARK1 | MAP/microtubule affinity-regulating kinase 1 |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MDM4 | MDM4, p53 regulator |
| MLC1 | megalencephalic leukoencephalopathy with subcortical cysts 1 |
| MLYCD | malonyl-CoA decarboxylase |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MYOZ3 | myozenin 3 |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| PC | pyruvate carboxylase |
| PCDHA9 | protocadherin alpha 9 |
| PIN1P1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1 |
| POLL | polymerase (DNA directed), lambda |
| PRAMEF10 | PRAME family member 10 |
| PRF1 | perforin 1 (pore forming protein) |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RPRM | reprimo, TP53 dependent G2 arrest mediator candidate |
| SCARA3 | scavenger receptor class A, member 3 |
| SCD5 | stearoyl-CoA desaturase 5 |
| SCIN | scinderin |
| SIX3 | SIX homeobox 3 |
| SLC10A1 | solute carrier family 10 (sodium/bile acid cotransporter), member 1 |
| SLC16A6 | solute carrier family 16, member 6 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SNRPN | small nuclear ribonucleoprotein polypeptide N |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 |
| TCP10 | t-complex 10 |
| TESPA1 | thymocyte expressed, positive selection associated 1 |
| TEX15 | testis expressed 15 |
| TIGD6 | tigger transposable element derived 6 |
| TMEM74B | transmembrane protein 74B |
| TRAC | T cell receptor alpha constant |
| TRIM25 | tripartite motif containing 25 |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TSC22D4 | TSC22 domain family, member 4 |
| VGF | VGF nerve growth factor inducible |
| VGLL3 | vestigial-like family member 3 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZNF197 | zinc finger protein 197 |
| ZNF574 | zinc finger protein 574 |
| ZNF747 | zinc finger protein 747 |
