negative nitroblue tetrazolium (nbt) reduction test Gene Set

Dataset HPO Gene-Disease Associations
Category disease or phenotype associations
Type phenotype
Description In the NBT test, neutrophils change the colorless compound NBT into a compound with a deep blue color. If this test is negative (i.e., no blue color is produced), then this indicates a defect in superoxide-generating NADPH oxidase activity with inability to efficiently kill phagocytized bacteria. (Human Phenotype Ontology, HP_0003203)
External Link http://compbio.charite.de/hpoweb/showterm?id=HP:0003203
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Genes

4 genes associated with the negative nitroblue tetrazolium (nbt) reduction test phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.

Symbol Name
CYBA cytochrome b-245, alpha polypeptide
CYBB cytochrome b-245, beta polypeptide
NCF1 neutrophil cytosolic factor 1
NCF2 neutrophil cytosolic factor 2