negative regulation of DNA-binding transcription factor activity Gene Set

Dataset GO Biological Process Annotations 2023
Category structural or functional annotations
Type biological process
Description Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription. (Gene Ontology, GO_0043433)
External Link http://amigo.geneontology.org/amigo/term/GO_0043433
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Genes

150 genes participating in the negative regulation of DNA-binding transcription factor activity biological process from the curated GO Biological Process Annotations 2023 dataset.

Symbol Name
ADGRG3 adhesion G protein-coupled receptor G3
ADORA3 adenosine A3 receptor
AIM2 absent in melanoma 2
ANXA4 annexin A4
ARRB1 arrestin, beta 1
ARRB2 arrestin, beta 2
BCL3 B-cell CLL/lymphoma 3
BHLHE40 basic helix-loop-helix family, member e40
BMP7 bone morphogenetic protein 7
BRMS1 breast cancer metastasis suppressor 1
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
CACTIN cactin, spliceosome C complex subunit
CARD8 caspase recruitment domain family, member 8
CD200 CD200 molecule
CDK5RAP3 CDK5 regulatory subunit associated protein 3
CDKN2A cyclin-dependent kinase inhibitor 2A
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma
CHP1 calcineurin-like EF-hand protein 1
CHUK conserved helix-loop-helix ubiquitous kinase
CMKLR1 chemerin chemokine-like receptor 1
COMMD1 copper metabolism (Murr1) domain containing 1
COMMD6 COMM domain containing 6
COMMD7 COMM domain containing 7
CTNNBIP1 catenin, beta interacting protein 1
CYLD cylindromatosis (turban tumor syndrome)
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DAB2IP DAB2 interacting protein
DAP death-associated protein
DDIT3 DNA-damage-inducible transcript 3
E2F1 E2F transcription factor 1
E2F2 E2F transcription factor 2
EGLN1 egl-9 family hypoxia-inducible factor 1
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4
EOMES eomesodermin
ERBIN erbb2 interacting protein
ESR1 estrogen receptor 1
FLNA filamin A, alpha
FOXA2 forkhead box A2
FOXH1 forkhead box H1
FOXJ1 forkhead box J1
FOXP3 forkhead box P3
FOXS1 forkhead box S1
FZD6 frizzled class receptor 6
GAS6 growth arrest-specific 6
GFI1 growth factor independent 1 transcription repressor
GLIS2 GLIS family zinc finger 2
HAND1 heart and neural crest derivatives expressed 1
HAVCR2 hepatitis A virus cellular receptor 2
HDAC2 histone deacetylase 2
HDAC4 histone deacetylase 4
HES1 hes family bHLH transcription factor 1
HES6 hes family bHLH transcription factor 6
HEYL hes-related family bHLH transcription factor with YRPW motif-like
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IRAK1 interleukin-1 receptor-associated kinase 1
IRAK2 interleukin-1 receptor-associated kinase 2
IRAK3 interleukin-1 receptor-associated kinase 3
IRG1 immunoresponsive 1 homolog (mouse)
ITCH itchy E3 ubiquitin protein ligase
KDM1A lysine (K)-specific demethylase 1A
KEAP1 kelch-like ECH-associated protein 1
KLF4 Kruppel-like factor 4 (gut)
LRRC14 leucine rich repeat containing 14
LRRK2 leucine-rich repeat kinase 2
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast)
MAP2K5 mitogen-activated protein kinase kinase 5
MAP3K10 mitogen-activated protein kinase kinase kinase 10
MDFI MyoD family inhibitor
MEN1 multiple endocrine neoplasia I
MTURN maturin, neural progenitor differentiation regulator homolog (Xenopus)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NLRC3 NLR family, CARD domain containing 3
NLRC5 NLR family, CARD domain containing 5
NLRP12 NLR family, pyrin domain containing 12
NLRP2 NLR family, pyrin domain containing 2
NLRP2P NLR family, pyrin domain containing 2 pseudogene
NLRP3 NLR family, pyrin domain containing 3
NR0B1 nuclear receptor subfamily 0, group B, member 1
NR0B2 nuclear receptor subfamily 0, group B, member 2
NUPR1 nuclear protein, transcriptional regulator, 1
NWD1 NACHT and WD repeat domain containing 1
OTULIN OTU deubiquitinase with linear linkage specificity
PARP10 poly (ADP-ribose) polymerase family, member 10
PAXIP1 PAX interacting (with transcription-activation domain) protein 1
PEX14 peroxisomal biogenesis factor 14
PHB2 prohibitin 2
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PKD1 polycystic kidney disease 1 (autosomal dominant)
PKD2 polycystic kidney disease 2 (autosomal dominant)
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive)
PLA2G10 phospholipase A2, group X
POU4F2 POU class 4 homeobox 2
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme
PRMT2 protein arginine methyltransferase 2
PRNP prion protein
PROX1 prospero homeobox 1
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
PTCH1 patched 1
PTGIS prostaglandin I2 (prostacyclin) synthase
PYCARD PYD and CARD domain containing
PYDC1 PYD (pyrin domain) containing 1
PYDC2 pyrin domain containing 2
RB1 retinoblastoma 1
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1
RNF2 ring finger protein 2
RWDD3 RWD domain containing 3
SETD6 SET domain containing 6
SFRP4 secreted frizzled-related protein 4
SFRP5 secreted frizzled-related protein 5
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
SIK1 salt-inducible kinase 1
SIRT1 sirtuin 1
SMAD7 SMAD family member 7
SP100 SP100 nuclear antigen
SPI1 Spi-1 proto-oncogene
SUFU suppressor of fused homolog (Drosophila)
SUMO1 small ubiquitin-like modifier 1
T T, brachyury homolog (mouse)
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TAF3 TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1
TBX6 T-box 6
TCEAL7 transcription elongation factor A (SII)-like 7
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TFDP1 transcription factor Dp-1
TFDP3 transcription factor Dp family, member 3
TLR9 toll-like receptor 9
TMIGD3 transmembrane and immunoglobulin domain containing 3
TMSB4X thymosin beta 4, X-linked
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF4 tumor necrosis factor receptor superfamily, member 4
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TRAF3 TNF receptor-associated factor 3
TRIB1 tribbles pseudokinase 1
TRIM21 tripartite motif containing 21
TRIM37 tripartite motif containing 37
TRIM40 tripartite motif containing 40
UFL1 UFM1-specific ligase 1
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
WFS1 Wolfram syndrome 1 (wolframin)
WWP2 WW domain containing E3 ubiquitin protein ligase 2
XCL1 chemokine (C motif) ligand 1
ZC3H12A zinc finger CCCH-type containing 12A
ZNF431 zinc finger protein 431
ZNF675 zinc finger protein 675