negative regulation of MAPK cascade Gene Set

Dataset GO Biological Process Annotations 2023
Category structural or functional annotations
Type biological process
Description Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the MAPKKK cascade. (Gene Ontology, GO_0043409)
External Link http://amigo.geneontology.org/amigo/term/GO_0043409
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Genes

106 genes participating in the negative regulation of MAPK cascade biological process from the curated GO Biological Process Annotations 2023 dataset.

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ADIPOQ adiponectin, C1Q and collagen domain containing
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
APOE apolipoprotein E
BMP2 bone morphogenetic protein 2
BMP4 bone morphogenetic protein 4
BMP7 bone morphogenetic protein 7
CASC2 cancer susceptibility candidate 2 (non-protein coding)
CAV1 caveolin 1, caveolae protein, 22kDa
CAV3 caveolin 3
CBLC Cbl proto-oncogene C, E3 ubiquitin protein ligase
CD300A CD300a molecule
CDK5RAP3 CDK5 regulatory subunit associated protein 3
CNKSR3 CNKSR family member 3
DAB2IP DAB2 interacting protein
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1)
DEFB114 defensin, beta 114
DLG1 discs, large homolog 1 (Drosophila)
DUPD1 dual specificity phosphatase and pro isomerase domain containing 1
DUSP1 dual specificity phosphatase 1
DUSP10 dual specificity phosphatase 10
DUSP13 dual specificity phosphatase 13
DUSP16 dual specificity phosphatase 16
DUSP2 dual specificity phosphatase 2
DUSP26 dual specificity phosphatase 26 (putative)
DUSP3 dual specificity phosphatase 3
DUSP4 dual specificity phosphatase 4
DUSP5 dual specificity phosphatase 5
DUSP6 dual specificity phosphatase 6
DUSP7 dual specificity phosphatase 7
DUSP8 dual specificity phosphatase 8
DUSP9 dual specificity phosphatase 9
EMILIN1 elastin microfibril interfacer 1
EPHA4 EPH receptor A4
EPHB2 EPH receptor B2
EZR ezrin
FBLN1 fibulin 1
FLCN folliculin
FOXM1 forkhead box M1
FOXO1 forkhead box O1
GBA glucosidase, beta, acid
GBP1 guanylate binding protein 1, interferon-inducible
GPER1 G protein-coupled estrogen receptor 1
GSTP1 glutathione S-transferase pi 1
HYAL2 hyaluronoglucosaminidase 2
IGBP1 immunoglobulin (CD79A) binding protein 1
IGF1R insulin-like growth factor 1 receptor
IL1B interleukin 1, beta
INPP5K inositol polyphosphate-5-phosphatase K
IRAK3 interleukin-1 receptor-associated kinase 3
ITGB1BP1 integrin beta 1 binding protein 1
LAX1 lymphocyte transmembrane adaptor 1
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
LMO3 LIM domain only 3 (rhombotin-like 2)
LYN LYN proto-oncogene, Src family tyrosine kinase
MISO1 mitochondrial inner membrane subdomain organizer 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
NF1 neurofibromin 1
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PAQR3 progestin and adipoQ receptor family member III
PEBP1 phosphatidylethanolamine binding protein 1
PHB prohibitin
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PPARG peroxisome proliferator-activated receptor gamma
PPEF2 protein phosphatase, EF-hand calcium binding domain 2
PPIA peptidylprolyl isomerase A (cyclophilin A)
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PRDM15 PR domain containing 15
PRKCD protein kinase C, delta
PSCA prostate stem cell antigen
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
PTEN phosphatase and tensin homolog
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PTPRC protein tyrosine phosphatase, receptor type, C
PTPRJ protein tyrosine phosphatase, receptor type, J
PTPRR protein tyrosine phosphatase, receptor type, R
QARS1 glutaminyl-tRNA synthetase 1
RANBP9 RAN binding protein 9
RGS14 regulator of G-protein signaling 14
RGS2 regulator of G-protein signaling 2
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SH2B3 SH2B adaptor protein 3
SIRPA signal-regulatory protein alpha
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SMAD4 SMAD family member 4
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPRED1 sprouty-related, EVH1 domain containing 1
SPRED2 sprouty-related, EVH1 domain containing 2
SPRED3 sprouty-related, EVH1 domain containing 3
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SPRY2 sprouty homolog 2 (Drosophila)
SPRY3 sprouty homolog 3 (Drosophila)
SPRY4 sprouty homolog 4 (Drosophila)
STK38 serine/threonine kinase 38
STYXL2 serine/threonine/tyrosine interacting like 2
SYNJ2BP synaptojanin 2 binding protein
TIMP3 TIMP metallopeptidase inhibitor 3
TLR4 toll-like receptor 4
TNIP1 TNFAIP3 interacting protein 1
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
WNK2 WNK lysine deficient protein kinase 2