negative regulation of NF-kappaB transcription factor activity Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the transcription factor NF-kappaB. (Gene Ontology, GO_0032088)
External Link http://amigo.geneontology.org/amigo/term/GO:0032088
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Genes

66 genes participating in the negative regulation of NF-kappaB transcription factor activity biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
ACOD1 aconitate decarboxylase 1
ADORA3 adenosine A3 receptor
AIM2 absent in melanoma 2
ANXA4 annexin A4
ARRB1 arrestin, beta 1
ARRB2 arrestin, beta 2
BCL3 B-cell CLL/lymphoma 3
BMP7 bone morphogenetic protein 7
BRMS1L breast cancer metastasis-suppressor 1-like
CACTIN cactin, spliceosome C complex subunit
CD200 CD200 molecule
CDK5RAP3 CDK5 regulatory subunit associated protein 3
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CHUK conserved helix-loop-helix ubiquitous kinase
CMKLR1 chemerin chemokine-like receptor 1
COMMD1 copper metabolism (Murr1) domain containing 1
COMMD6 COMM domain containing 6
COMMD7 COMM domain containing 7
CYLD cylindromatosis (turban tumor syndrome)
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DAB2IP DAB2 interacting protein
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3
ERBIN erbb2 interacting protein
FOXJ1 forkhead box J1
FOXP3 forkhead box P3
GFI1 growth factor independent 1 transcription repressor
HAVCR2 hepatitis A virus cellular receptor 2
IRAK3 interleukin-1 receptor-associated kinase 3
ITCH itchy E3 ubiquitin protein ligase
LRRC14 leucine rich repeat containing 14
MTURN maturin, neural progenitor differentiation regulator homolog (Xenopus)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NLRC3 NLR family, CARD domain containing 3
NLRC5 NLR family, CARD domain containing 5
NLRP12 NLR family, pyrin domain containing 12
NLRP2B NLR family pyrin domain containing 2B
NWD1 NACHT and WD repeat domain containing 1
OTULIN OTU deubiquitinase with linear linkage specificity
PARP10 poly (ADP-ribose) polymerase family, member 10
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive)
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme
PRMT2 protein arginine methyltransferase 2
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
PTGIS prostaglandin I2 (prostacyclin) synthase
PYCARD PYD and CARD domain containing
PYDC1 PYD (pyrin domain) containing 1
PYDC2 pyrin domain containing 2
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1
RWDD3 RWD domain containing 3
SETD6 SET domain containing 6
SIRT1 sirtuin 1
SIVA1 SIVA1, apoptosis-inducing factor
SPI1 Spi-1 proto-oncogene
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1
TCEAL7 transcription elongation factor A (SII)-like 7
TMIGD3 transmembrane and immunoglobulin domain containing 3
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TRAF3 TNF receptor-associated factor 3
TRIM21 tripartite motif containing 21
TRIM37 tripartite motif containing 37
TRIM40 tripartite motif containing 40
UFL1 UFM1-specific ligase 1
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
ZC3H12A zinc finger CCCH-type containing 12A
ZNF675 zinc finger protein 675