negative regulation of TORC1 signaling Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
External Link http://amigo.geneontology.org/amigo/term/GO:1904262
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Genes

50 genes participating in the negative regulation of TORC1 signaling biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
AKT1S1 AKT1 substrate 1 (proline-rich)
ATM ATM serine/threonine kinase
ATXN3 ataxin 3
ATXN3L ataxin 3-like
CASTOR1 cytosolic arginine sensor for mTORC1 subunit 1
CASTOR2 cytosolic arginine sensor for mTORC1 subunit 2
DEPDC5 DEP domain containing 5
DEPTOR DEP domain containing MTOR-interacting protein
ITFG2 integrin alpha FG-GAP repeat containing 2
KICS2 KICSTOR subunit 2
KPTN kaptin (actin binding protein)
MAPK3 mitogen-activated protein kinase 3
MIOS missing oocyte, meiosis regulator, homolog (Drosophila)
NLK nemo-like kinase
NPC1 Niemann-Pick disease, type C1
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae)
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae)
OTUD7B OTU deubiquitinase 7B
PELI1 pellino E3 ubiquitin protein ligase 1
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PRKCA protein kinase C, alpha
RNF152 ring finger protein 152
RNF167 ring finger protein 167
SAMTOR S-adenosylmethionine sensor upstream of mTORC1
SAR1A secretion associated, Ras related GTPase 1A
SAR1B secretion associated, Ras related GTPase 1B
SEC13 SEC13 homolog (S. cerevisiae)
SEH1L SEH1-like (S. cerevisiae)
SESN1 sestrin 1
SESN2 sestrin 2
SESN3 sestrin 3
SPAAR small regulatory polypeptide of amino acid response
STK11 serine/threonine kinase 11
SZT2 seizure threshold 2 homolog (mouse)
TBC1D7 TBC1 domain family, member 7
TBK1 TANK-binding kinase 1
TSC1 tuberous sclerosis 1
TSC2 tuberous sclerosis 2
UBE2D1 ubiquitin-conjugating enzyme E2D 1
UBE2N ubiquitin-conjugating enzyme E2N
UBE2W ubiquitin-conjugating enzyme E2W (putative)
UBE3A ubiquitin protein ligase E3A
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
WDR24 WD repeat domain 24
WDR59 WD repeat domain 59
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta