negative regulation of angiogenesis Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description Any process that stops, prevents, or reduces the frequency, rate or extent of angiogenesis. (Gene Ontology, GO_0016525)
External Link http://amigo.geneontology.org/amigo/term/GO:0016525
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Genes

94 genes participating in the negative regulation of angiogenesis biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9
ADGRB1 adhesion G protein-coupled receptor B1
AGO1 argonaute RISC catalytic component 1
ALOX5 arachidonate 5-lipoxygenase
AMOT angiomotin
ANGPT4 angiopoietin 4
APOH apolipoprotein H (beta-2-glycoprotein I)
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
CCN6 cellular communication network factor 6
CCR2 chemokine (C-C motif) receptor 2
CD160 CD160 molecule
CD36 CD36 molecule (thrombospondin receptor)
CLDN5 claudin 5
CNMD chondromodulin
COL4A2 collagen, type IV, alpha 2
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
CREB3L1 cAMP responsive element binding protein 3-like 1
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTNND1 catenin (cadherin-associated protein), delta 1
CXCL10 chemokine (C-X-C motif) ligand 10
CXCR3 chemokine (C-X-C motif) receptor 3
DAB2IP DAB2 interacting protein
DCN decorin
E2F2 E2F transcription factor 2
ECSCR endothelial cell surface expressed chemotaxis and apoptosis regulator
EFNA3 ephrin-A3
EMILIN1 elastin microfibril interfacer 1
EPN1 epsin 1
EPN2 epsin 2
FASLG Fas ligand (TNF superfamily, member 6)
FOXC1 forkhead box C1
FOXJ2 forkhead box J2
FOXO4 forkhead box O4
GDF2 growth differentiation factor 2
GDNF glial cell derived neurotrophic factor
GHRL ghrelin/obestatin prepropeptide
GTF2I general transcription factor IIi
HGS hepatocyte growth factor-regulated tyrosine kinase substrate
HHEX hematopoietically expressed homeobox
HLA-G major histocompatibility complex, class I, G
HOXA5 homeobox A5
HSPG2 heparan sulfate proteoglycan 2
IL17F interleukin 17F
ISM1 isthmin 1, angiogenesis inhibitor
KLF2 Kruppel-like factor 2
KLF4 Kruppel-like factor 4 (gut)
KLKB1 kallikrein B, plasma (Fletcher factor) 1
KRIT1 KRIT1, ankyrin repeat containing
MECP2 methyl CpG binding protein 2
MINAR1 membrane integral NOTCH2 associated receptor 1
NAXE NAD(P)HX epimerase
NPPB natriuretic peptide B
NPR1 natriuretic peptide receptor 1
PDE3B phosphodiesterase 3B, cGMP-inhibited
PF4 platelet factor 4
PGK1 phosphoglycerate kinase 1
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PML promyelocytic leukemia
PPARG peroxisome proliferator-activated receptor gamma
PRL prolactin
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTPRM protein tyrosine phosphatase, receptor type, M
QKI QKI, KH domain containing, RNA binding
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RGCC regulator of cell cycle
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
SARS1 seryl-tRNA synthetase 1
SEMA3E sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC48A1 solute carrier family 48 (heme transporter), member 1
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPINK5 serine peptidase inhibitor, Kazal type 5
SPRED1 sprouty-related, EVH1 domain containing 1
SPRY2 sprouty homolog 2 (Drosophila)
STAB1 stabilin 1
STAT1 signal transducer and activator of transcription 1, 91kDa
SULF1 sulfatase 1
SYNJ2BP synaptojanin 2 binding protein
TEK TEK tyrosine kinase, endothelial
TGFB2 transforming growth factor, beta 2
THBS1 thrombospondin 1
THBS2 thrombospondin 2
THBS4 thrombospondin 4
TNF tumor necrosis factor
TNMD tenomodulin
VASH1 vasohibin 1
YJEFN3 YjeF N-terminal domain containing 3
ZNF354C zinc finger protein 354C