negative regulation of autophagy Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description Any process that stops, prevents, or reduces the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm. (Gene Ontology, GO_0010507)
External Link http://amigo.geneontology.org/amigo/term/GO:0010507
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Genes

66 genes participating in the negative regulation of autophagy biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BMF Bcl2 modifying factor
CPTP ceramide-1-phosphate transfer protein
CTSA cathepsin A
DAPL1 death associated protein-like 1
DNPEP aspartyl aminopeptidase
EIF4E eukaryotic translation initiation factor 4E
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3
EP300 E1A binding protein p300
ERFE erythroferrone
FOXK1 forkhead box K1
FOXK2 forkhead box K2
GOLGA2 golgin A2
IL10 interleukin 10
IL10RA interleukin 10 receptor, alpha
KDM4A lysine (K)-specific demethylase 4A
KIF25 kinesin family member 25
KLHL22 kelch-like family member 22
LEP leptin
LEPROT leptin receptor overlapping transcript
LRRK2 leucine-rich repeat kinase 2
LZTS1 leucine zipper, putative tumor suppressor 1
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MCL1 myeloid cell leukemia 1
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae)
MTMR9 myotubularin related protein 9
MTOR mechanistic target of rapamycin (serine/threonine kinase)
NRBP2 nuclear receptor binding protein 2
NUPR1 nuclear protein, transcriptional regulator, 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PINK1 PTEN induced putative kinase 1
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
QSOX1 quiescin Q6 sulfhydryl oxidase 1
RASIP1 Ras interacting protein 1
RPTOR regulatory associated protein of MTOR, complex 1
RRAGA Ras-related GTP binding A
RRAGB Ras-related GTP binding B
RRAGC Ras-related GTP binding C
RRAGD Ras-related GTP binding D
RUBCN rubicon autophagy regulator
SIRT2 sirtuin 2
SLTM SAFB-like, transcription modulator
SMCR8 Smith-Magenis syndrome chromosome region, candidate 8
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1)
SOS1 son of sevenless homolog 1 (Drosophila)
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STK38L serine/threonine kinase 38 like
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2
TAB3 TGF-beta activated kinase 1/MAP3K7 binding protein 3
TBC1D14 TBC1 domain family, member 14
TLK2 tousled-like kinase 2
TREM2 triggering receptor expressed on myeloid cells 2
TRIM27 tripartite motif containing 27
TSC1 tuberous sclerosis 1
USP36 ubiquitin specific peptidase 36
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
WASHC1 WASH complex subunit 1
WDR6 WD repeat domain 6
WNK1 WNK lysine deficient protein kinase 1
ZKSCAN3 zinc finger with KRAB and SCAN domains 3