negative regulation of cartilage development Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description Any process that decreases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate. (Gene Ontology, GO_0061037)
External Link http://amigo.geneontology.org/amigo/term/GO:0061037
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Genes

15 genes participating in the negative regulation of cartilage development biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7
CHADL chondroadherin-like
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
GDF5 growth differentiation factor 5
GREM1 gremlin 1, DAN family BMP antagonist
NKX3-2 NK3 homeobox 2
NR5A2 nuclear receptor subfamily 5, group A, member 2
PTHLH parathyroid hormone-like hormone
PTPN11 protein tyrosine phosphatase, non-receptor type 11
SNAI2 snail family zinc finger 2
SOX9 SRY (sex determining region Y)-box 9
TGFBR1 transforming growth factor, beta receptor 1
WNT11 wingless-type MMTV integration site family, member 11
WNT9A wingless-type MMTV integration site family, member 9A