Any process that decreases the frequency, rate or extent of centrosome duplication. Centrosome duplication is the replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized. (Gene Ontology, GO_0010826)
11 genes participating in the negative regulation of centrosome duplication biological process from the curated GO Biological Process Annotations 2025 dataset.
