negative regulation of complement activation Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation. (Gene Ontology, GO_0045916)
External Link http://amigo.geneontology.org/amigo/term/GO:0045916
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Genes

13 genes participating in the negative regulation of complement activation biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
A2M alpha-2-macroglobulin
C4BPA complement component 4 binding protein, alpha
C4BPB complement component 4 binding protein, beta
CD46 CD46 molecule, complement regulatory protein
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD59 CD59 molecule, complement regulatory protein
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CR1L complement component (3b/4b) receptor 1-like
CR2 complement component (3d/Epstein Barr virus) receptor 2
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SUSD4 sushi domain containing 4
VSIG4 V-set and immunoglobulin domain containing 4